The Atypical Kinase RIOK3 Limits RVFV Propagation and Is Regulated by Alternative Splicing

Impact of mRNA chemistry and manufacturing process on innate immune activation

(2020) Jennifer Nelson et al.   Science Advances

Transcriptome profiling in Rift Valley fever virus infected cells reveals modified transcriptional and alternative splicing programs

(2019) Katherine E. Havranek et al.   PLoS One

Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection

(2019) Nandan S. Gokhale et al.   MOLECULAR CELL

The atypical protein kinase RIOK3 contributes to glioma cell proliferation/survival, migration/invasion and the AKT/mTOR signaling pathway

(2018) Tong Zhang et al.   CANCER LETTERS

A Cytoplasmic RNA Virus Alters the Function of the Cell Splicing Protein SRSF2

(2017) Efraín E. Rivera-Serrano et al.   JOURNAL OF VIROLOGY

Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes

(2017) Ashley M. Jacobi et al.   METHODS

Alternative splicing as a regulator of development and tissue identity

(2017) Francisco E. Baralle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Environmental perturbations lead to extensive directional shifts in RNA processing

(2017) Allison L. Richards et al.   PLoS Genetics

Mechanism and regulation of the nonsense-mediated decay pathway

(2016) Nele Hug et al.   NUCLEIC ACIDS RESEARCH

The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing

(2016) Federico A. De Maio et al.   PLoS Pathogens

Association of Rift Valley fever virus infection with miscarriage in Sudanese women: a cross-sectional study

(2016) Maria Baudin et al.   Lancet Global Health

Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions

(2016) Simon Boudreault et al.   PLoS One

Viral RNA detection by RIG-I-like receptors

(2015) Mitsutoshi Yoneyama et al.   CURRENT OPINION IN IMMUNOLOGY

Transfected Poly(I:C) Activates Different dsRNA Receptors, Leading to Apoptosis or Immunoadjuvant Response in Androgen-independent Prostate Cancer Cells

(2015) Sara Palchetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GenBank

(2015) Karen Clark et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Analysis of Alternative Splicing Landscapes Modulated during Plant-Virus Interactions inBrachypodium distachyon

(2015) Kranthi K. Mandadi et al.   PLANT CELL

Transmission of innate immune signaling by packaging of cGAMP in viral particles

(2015) Matteo Gentili et al.   SCIENCE

Method for quantitative analysis of nonsense-mediated mRNA decay at the single cell level

(2015) Anton P. Pereverzev et al.   Scientific Reports

RIOK3-Mediated Phosphorylation of MDA5 Interferes with Its Assembly and Attenuates the Innate Immune Response

(2015) Ken Takashima et al.   Cell Reports

Association of Symptoms and Severity of Rift Valley Fever with Genetic Polymorphisms in Human Innate Immune Pathways

(2015) Amy G. Hise et al.   PLoS Neglected Tropical Diseases

RIOK3 Is an Adaptor Protein Required for IRF3-Mediated Antiviral Type I Interferon Production

(2014) Jun Feng et al.   JOURNAL OF VIROLOGY

Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing

(2014) Dirk Heckl et al.   NATURE BIOTECHNOLOGY

Context-dependent control of alternative splicing by RNA-binding proteins

(2014) Xiang-Dong Fu et al.   NATURE REVIEWS GENETICS

Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis

(2014) D C Singleton et al.   ONCOGENE

In Vivo Ligands of MDA5 and RIG-I in Measles Virus-Infected Cells

(2014) Simon Runge et al.   PLoS Pathogens

Restoration of the Normal Splicing Pattern of the PLP1 Gene by Means of an Antisense Oligonucleotide Directed against an Exonic Mutation

(2013) Stefano Regis et al.   PLoS One

Host Cell Transcriptome Profile during Wild-Type and Attenuated Dengue Virus Infection

(2013) October M. Sessions et al.   PLoS Neglected Tropical Diseases

Human RioK3 is a novel component of cytoplasmic pre-40S pre-ribosomal particles

(2012) Kamila Baumas et al.   RNA Biology

Rift Valley fever virus NSs inhibits host transcription independently of the degradation of dsRNA-dependent protein kinase PKR

(2012) Birte Kalveram et al.   VIROLOGY

The Toll-Like Receptor 3-Mediated Antiviral Response Is Important for Protection against Poliovirus Infection in Poliovirus Receptor Transgenic Mice

(2011) Y. Abe et al.   JOURNAL OF VIROLOGY

The Pathogenesis of Rift Valley Fever

(2011) Tetsuro Ikegami et al.   Viruses-Basel

Tissue Tropism and Target Cells of NSs-Deleted Rift Valley Fever Virus in Live Immunodeficient Mice

(2011) Céline Gommet et al.   PLoS Neglected Tropical Diseases

Novel splice variants of human IKKε negatively regulate IKKε-induced IRF3 and NF-kB activation

(2010) Anja Koop et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Strain-to-strain difference of V protein of measles virus affects MDA5-mediated IFN-β-inducing potential

(2010) Hiromi Takaki et al.   MOLECULAR IMMUNOLOGY

Rift Valley Fever Virus NSs Protein Promotes Post-Transcriptional Downregulation of Protein Kinase PKR and Inhibits eIF2α Phosphorylation

(2009) Tetsuro Ikegami et al.   PLoS Pathogens

Alternative splicing and disease

(2008) Jamal Tazi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Negative Regulation of Virus-triggered IFN-β Signaling Pathway by Alternative Splicing of TBK1

(2008) Weiwen Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling☆

(2008) Sonya P. Lad et al.   MOLECULAR IMMUNOLOGY

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

(2008) Matthias Habjan et al.   PLoS One

A SAP30 Complex Inhibits IFN-β Expression in Rift Valley Fever Virus Infected Cells

(2008) Nicolas Le May et al.   PLoS Pathogens