RIOK3 Is an Adaptor Protein Required for IRF3-Mediated Antiviral Type I Interferon Production

RIO kinase 3 acts as a SUFU-dependent positive regulator of Hedgehog signaling

(2013) Melanie Tariki et al.   CELLULAR SIGNALLING

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

(2012) L. Sun et al.   SCIENCE

IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection

(2011) Nagaraj Kerur et al.   Cell Host & Microbe

Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses

(2011) Glen N Barber   CURRENT OPINION IN IMMUNOLOGY

miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1

(2011) L. Zhang et al.   GENES & DEVELOPMENT

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

(2011) Zhiqiang Zhang et al.   NATURE IMMUNOLOGY

Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity

(2010) Evelyn Dixit et al.   CELL

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

Regulation of the cytosolic DNA-sensing system in innate immunity: a current view

(2009) Hideyuki Yanai et al.   CURRENT OPINION IN IMMUNOLOGY

RIOK3 interacts with caspase-10 and negatively regulates the NF-κB signaling pathway

(2009) Jingxuan Shan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

(2009) W. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY

Persistent Gammaherpesvirus Replication and Dynamic Interaction with the Host In Vivo

(2008) S. Hwang et al.   JOURNAL OF VIROLOGY

MPYS, a Novel Membrane Tetraspanner, Is Associated with Major Histocompatibility Complex Class II and Mediates Transduction of Apoptotic Signals

(2008) L. Jin et al.   MOLECULAR AND CELLULAR BIOLOGY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE