Dynamic Plasma Membrane Organization: A Complex Symphony

Lipid Rafts: Controversies Resolved, Mysteries Remain

(2020) Ilya Levental et al.   TRENDS IN CELL BIOLOGY

Site‐specific functionality and tryptophan mimicry of lipidation in Tetraspanin CD9

(2020) Viviana Neviani et al.   FEBS Journal

Actin Cell Cortex: Structure and Molecular Organization

(2020) Tatyana M. Svitkina   TRENDS IN CELL BIOLOGY

A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking

(2020) Katherine J Susa et al.   eLife

Differential organization of tonic and chronic B cell antigen receptors in the plasma membrane

(2019) Maria Angela Gomes de Castro et al.   Nature Communications

Integrin Mechano-chemical Signaling Generates Plasma Membrane Nanodomains that Promote Cell Spreading

(2019) Joseph Mathew Kalappurakkal et al.   CELL

CD81 is a novel immunotherapeutic target for B cell lymphoma

(2019) Felipe Vences-Catalán et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation

(2019) Madison Bolger-Munro et al.   eLife

Migrasome formation is mediated by assembly of micron-scale tetraspanin macrodomains

(2019) Yuwei Huang et al.   NATURE CELL BIOLOGY

Dynamic actin-mediated nano-scale clustering of CD44 regulates its meso-scale organization at the plasma membrane

(2019) Parijat Sil et al.   MOLECULAR BIOLOGY OF THE CELL

TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering

(2019) Edoardo Moretto et al.   Cell Reports

High-throughput, single-particle tracking reveals nested membrane domains that dictate KRasG12D diffusion and trafficking

(2019) Yerim Lee et al.   eLife

Sweetening the hallmarks of cancer: Galectins as multifunctional mediators of tumor progression

(2019) María Romina Girotti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement

(2018) Spencer A. Freeman et al.   CELL

Galectins at a glance

(2018) Ludger Johannes et al.   JOURNAL OF CELL SCIENCE

The Lack of WIP Binding to Actin Results in Impaired B Cell Migration and Altered Humoral Immune Responses

(2018) Selina Jessica Keppler et al.   Cell Reports

Galectin-9 binds IgM-BCR to regulate B cell signaling

(2018) Anh Cao et al.   Nature Communications

Capturing suboptical dynamic structures in lipid bilayer patches formed from free-standing giant unilamellar vesicles

(2017) Tripta Bhatia et al.   Nature Protocols

The mystery of membrane organization: composition, regulation and roles of lipid rafts

(2017) Erdinc Sezgin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tetraspanin microdomains control localized protein kinase C signaling in B cells

(2017) Malou Zuidscherwoude et al.   Science Signaling

Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments

(2017) David Richter et al.   Nature Communications

Self-organizing actin patterns shape membrane architecture but not cell mechanics

(2017) M. Fritzsche et al.   Nature Communications

Structural determinants and functional consequences of protein affinity for membrane rafts

(2017) Joseph H. Lorent et al.   Nature Communications

Protein sorting by lipid phase-like domains supports emergent signaling function in B lymphocyte plasma membranes

(2017) Matthew B Stone et al.   eLife

Tetraspanin microdomains control localized protein kinase C signaling in B cells

(2017) Malou Zuidscherwoude et al.   Science Signaling

The specificity of homomeric clustering of CD81 is mediated by its δ-loop

(2017) Yahya Homsi et al.   FEBS Open Bio

Membrane Rafts in T Cell Activation: A Spotlight on CD28 Costimulation

(2017) Sara Zumerle et al.   Frontiers in Immunology

HIV virions sense plasma membrane heterogeneity for cell entry

(2017) Sung-Tae Yang et al.   Science Advances

Spatial distribution and activity of Na + /K + -ATPase in lipid bilayer membranes with phase boundaries

(2016) Tripta Bhatia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Assessment of CD37 B-cell antigen and cell-of-origin significantly improves risk prediction in diffuse large B-cell lymphoma

(2016) Z. Y. Xu-Monette et al.   BLOOD

Resistance to anti-CD19/CD3 BiTE in acute lymphoblastic leukemia may be mediated by disrupted CD19 membrane trafficking

(2016) Friederike Braig et al.   BLOOD

Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket

(2016) Brandon Zimmerman et al.   CELL

Glycosylation-Dependent IFN-γR Partitioning in Lipid and Actin Nanodomains Is Critical for JAK Activation

(2016) Cédric M. Blouin et al.   CELL

Tetraspanin CD37 protects against the development of B cell lymphoma

(2016) Charlotte M. de Winde et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanistic insights into the distribution of carbohydrate clusters on cell membranes revealed by dSTORM imaging

(2016) Junling Chen et al.   Nanoscale

Kinetic disruption of lipid rafts is a mechanosensor for phospholipase D

(2016) E. Nicholas Petersen et al.   Nature Communications

A major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion

(2016) Anne-Elisabeth Petit et al.   Nature Communications

Tetraspanin CD82 Regulates the Spatiotemporal Dynamics of PKCα in Acute Myeloid Leukemia

(2016) Christina M. Termini et al.   Scientific Reports

Tetraspanin CD82: a suppressor of solid tumors and a modulator of membrane heterogeneity

(2015) Jin Feng et al.   CANCER AND METASTASIS REVIEWS

CD151 promotes α3β1 integrin-dependent organization of carcinoma cell junctions and restrains collective cell invasion

(2015) Shannin C Zevian et al.   CANCER BIOLOGY & THERAPY

Transbilayer Lipid Interactions Mediate Nanoclustering of Lipid-Anchored Proteins

(2015) Riya Raghupathy et al.   CELL

Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling

(2015) F. Gasparrini et al.   EMBO JOURNAL

Tetraspanin CD37 Regulates β2Integrin–Mediated Adhesion and Migration in Neutrophils

(2015) Janet L. Wee et al.   JOURNAL OF IMMUNOLOGY

Tetraspanin CD82 regulates bone marrow homing of acute myeloid leukemia by modulating the molecular organization of N-cadherin

(2015) K D Marjon et al.   ONCOGENE

The tetraspanin web revisited by super-resolution microscopy

(2015) Malou Zuidscherwoude et al.   Scientific Reports

Actin Migration Driven by Directional Assembly and Disassembly of Membrane-Anchored Actin Filaments

(2015) Hiroko Katsuno et al.   Cell Reports

Editorial: Membrane domains as new drug targets

(2015) Annemiek B. van Spriel et al.   Frontiers in Physiology

The Extracellular δ-Domain is Essential for the Formation of CD81 Tetraspanin Webs

(2014) Yahya Homsi et al.   BIOPHYSICAL JOURNAL

Tetraspanins CD9 and CD151 at the immune synapse support T-cell integrin signaling

(2014) Vera Rocha-Perugini et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nanoclustering as a dominant feature of plasma membrane organization

(2014) M. F. Garcia-Parajo et al.   JOURNAL OF CELL SCIENCE

The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density

(2014) Christina M. Termini et al.   MOLECULAR BIOLOGY OF THE CELL

Lateral diffusion in a discrete fluid membrane with immobile particles

(2014) Ziya Kalay et al.   PHYSICAL REVIEW E

The Tetraspanin CD53 Modulates Responses from Activating NK Cell Receptors, Promoting LFA-1 Activation and Dampening NK Cell Effector Functions

(2014) Izabela Todros-Dawda et al.   PLoS One

Enhanced receptor-clathrin interactions induced by N-glycan-mediated membrane micropatterning

(2014) J. A. Torreno-Pina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane raft association is a determinant of plasma membrane localization

(2014) B. B. Diaz-Rohrer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Fluid—Mosaic Model of Membrane Structure: Still relevant to understanding the structure, function and dynamics of biological membranes after more than 40years

(2013) Garth L. Nicolson   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Actin and Tetraspanin Networks Organize Receptor Nanoclusters to Regulate B Cell Receptor-Mediated Signaling

(2013) Pieta K. Mattila et al.   IMMUNITY

CD81 Controls Sustained T Cell Activation Signaling and Defines the Maturation Stages of Cognate Immunological Synapses

(2013) V. Rocha-Perugini et al.   MOLECULAR AND CELLULAR BIOLOGY

Active Remodeling of Cortical Actin Regulates Spatiotemporal Organization of Cell Surface Molecules

(2012) Kripa Gowrishankar et al.   CELL

Structural Basis of Ligand Interactions of the Large Extracellular Domain of Tetraspanin CD81

(2012) Sundaresan Rajesh et al.   JOURNAL OF VIROLOGY

The Tetraspanin CD37 Orchestrates the  4 1 Integrin-Akt Signaling Axis and Supports Long-Lived Plasma Cell Survival

(2012) A. B. van Spriel et al.   Science Signaling

Dynamic Organizing Principles of the Plasma Membrane that Regulate Signal Transduction: Commemorating the Fortieth Anniversary of Singer and Nicolson's Fluid-Mosaic Model

(2011) Akihiro Kusumi et al.   Annual Review of Cell and Developmental Biology

The immunological synapse: a cause or consequence of T-cell receptor triggering?

(2011) Balbino Alarcón et al.   IMMUNOLOGY

Greasing Their Way: Lipid Modifications Determine Protein Association with Membrane Rafts

(2010) Ilya Levental et al.   BIOCHEMISTRY

Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse

(2010) Rémi Lasserre et al.   EMBO JOURNAL

Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms

(2008) Olga Barreiro et al.   JOURNAL OF CELL BIOLOGY

Single-molecule analysis of CD9 dynamics and partitioning reveals multiple modes of interaction in the tetraspanin web

(2008) Cedric Espenel et al.   JOURNAL OF CELL BIOLOGY

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

(2008) Christian Eggeling et al.   NATURE

Targeting of tetraspanin proteins — potential benefits and strategies

(2008) Martin E. Hemler   NATURE REVIEWS DRUG DISCOVERY