Zebrafish (Danio rerio) using as model for genotoxicity and DNA repair assessments: Historical review, current status and trends

Evaluation of the Oxidative Stress Status in Zebrafish (Danio rerio) Liver Induced by Three Typical Organic UV Filters (BP-4, PABA and PBSA)

(2020) Xinxin Huang et al.   International Journal of Environmental Research and Public Health

Nodularin induced oxidative stress contributes to developmental toxicity in zebrafish embryos

(2020) Guoliang Chen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Common mechanisms activated in the tissues of aquatic and terrestrial animal models after TiO2 nanoparticles exposure

(2020) Dimitra Bobori et al.   ENVIRONMENT INTERNATIONAL

Fluoxastrobin-induced effects on acute toxicity, development toxicity, oxidative stress, and DNA damage in Danio rerio embryos

(2020) Cheng Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Technical Updates to the Comet Assay In Vivo for Assessing DNA Damage in Zebrafish Embryos from Fresh and Frozen Cell Suspensions

(2020) Carla Martins et al.   Zebrafish

Linking urbanization, human capital, and the ecological footprint in G7 countries: An empirical analysis

(2020) Zahoor Ahmed et al.   Sustainable Cities and Society

Biochemical and genotoxic biomarkers and cell cycle assessment in the zebrafish liver (ZF-L) cell line exposed to the novel metal-insecticide magnesium-hespiridin complex

(2020) Marina Marques Bonomo et al.   CHEMOSPHERE

Exposure route affects the distribution and toxicity of polystyrene nanoplastics in zebrafish

(2020) Rui Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Comparative developmental toxicity of iron oxide nanoparticles and ferric chloride to zebrafish (Danio rerio) after static and semi-static exposure

(2020) Aryelle Canedo Pereira et al.   CHEMOSPHERE

Zebrafish as a preclinical in vivo screening model for nanomedicines

(2019) Sandro Sieber et al.   ADVANCED DRUG DELIVERY REVIEWS

The application of the Comet assay in fish cell lines

(2019) Bojana Žegura et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation

(2019) Yavor Hadzhiev et al.   Nature Communications

Cypermethrin induction of DNA damage and oxidative stress in zebrafish gill cells

(2019) E.V. Paravani et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Impact of the glyphosate-based commercial herbicide, its components and its metabolite AMPA on non-target aquatic organisms

(2019) Laís de Brito Rodrigues et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The comet assay in animal models: From bugs to whales – (Part 2 Vertebrates)

(2019) Goran Gajski et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

AP endonuclease 1 (Apex1) influences brain development linking oxidative stress and DNA repair

(2019) De-Sheng Pei et al.   Cell Death & Disease

DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging

(2019) Vinod Tiwari et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The zebrafish embryotoxicity test (ZET) for nanotoxicity assessment: from morphological to molecular approach

(2019) Aryelle Canedo Pereira et al.   ENVIRONMENTAL POLLUTION

Stress response and toxicity studies on zebrafish exposed to endosulfan and imidacloprid present in water

(2019) Barzah Muazzam et al.   JOURNAL OF WATER SUPPLY RESEARCH AND TECHNOLOGY-AQUA

Bis(2-ethylhexyl) phthalate induces DNA strand breaks and gene expression alterations in larval zebrafish Danio rerio

(2019) Halis Boran et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Characterization of different DNA repair pathways in hepatic cells of Zebrafish (Danio rerio)

(2019) Simone Rutz Costa et al.   DNA REPAIR

A sensitive refining of in vitro and in vivo toxicological behavior of green synthesized ZnO nanoparticles from the shells of Jatropha curcas for multifunctional biomaterials development

(2019) R. Suriyaprabha et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Dual drug loaded PLGA nanospheres for synergistic efficacy in breast cancer therapy

(2019) Murugesan Sathiya Deepika et al.   Materials Science & Engineering C-Materials for Biological Applications

Nucleotide excision repair genes shaping embryonic development

(2019) Sofia J. Araújo et al.   Open Biology

Nitroaromatic compounds damage the DNA of zebrafish embryos (Danio rerio)

(2019) Daniel Koske et al.   AQUATIC TOXICOLOGY

Heat stress modulates nucleotide excision repair capacity in zebrafish (Danio rerio) early and mid-early embryos via distinct mechanisms

(2019) Liu-Chun Chien et al.   CHEMOSPHERE

Emergent contaminants in sediments and fishes from the Tamsui River (Taiwan): Their spatial-temporal distribution and risk to aquatic ecosystems and human health

(2019) Ching-Chang Lee et al.   ENVIRONMENTAL POLLUTION

Tritiated Water Exposure in Zebrafish ( Danio rerio ): Effects on the Early‐Life Stages

(2019) Béatrice Gagnaire et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Application of the comet assay in human biomonitoring: An hCOMET perspective

(2019) Amaya Azqueta et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Genetic and epigenetic alterations induced by bisphenol A exposure during different periods of spermatogenesis: from spermatozoa to the progeny

(2019) Marta Lombó et al.   Scientific Reports

Histopathological, genotoxic, and behavioral damages induced by manganese (II) in adult zebrafish

(2019) Gabriela Zimmermann Prado Rodrigues et al.   CHEMOSPHERE

Oxidative stress, cell cycle arrest, DNA damage and apoptosis in adult zebrafish ( Danio rerio ) induced by tris(1,3-dichloro-2-propyl) phosphate

(2018) Hanyan Chen et al.   AQUATIC TOXICOLOGY

Toxicokinetic and toxicodynamic of depleted uranium in the zebrafish, Danio rerio

(2018) Olivier Simon et al.   AQUATIC TOXICOLOGY

Modulations of TCDD-mediated induction of zebrafish cyp1a1 and the AHR pathway by administering Cd 2+ in vivo

(2018) Ying Ying Chen et al.   CHEMOSPHERE

Comparative evaluation of toxicological effects and recovery patterns in zebrafish ( Danio rerio ) after exposure to phosalone-based and cypermethrin-based pesticides

(2018) Volkan Korkmaz et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The interactions of fullerene C 60 and Benzo(α)pyrene influence their bioavailability and toxicity to zebrafish embryos

(2018) Camilla Della Torre et al.   ENVIRONMENTAL POLLUTION

Molecular Toxicity of Metal Oxide Nanoparticles in Danio rerio

(2018) Jing Hou et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Toxicological study of the degradation products of antineoplastic agent etoposide in commercial formulation treated by heterogeneous photocatalysis using SrSnO3

(2018) Idio Alves de Sousa Filho et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Testis transcriptome alterations in zebrafish (Danio rerio) with reduced fertility due to developmental exposure to 17α-ethinyl estradiol

(2018) T. Porseryd et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Cypermethrin: Oxidative stress and genotoxicity in retinal cells of the adult zebrafish

(2018) E.V. Paravani et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Acute and chronic toxic effects of fluoxastrobin on zebrafish ( Danio rerio )

(2018) Cheng Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Comparison of the Base Excision Repair Activity in Liver Cell Models of Zebrafish (Danio rerio)

(2018) Simone Rutz Costa et al.   Zebrafish

Co-exposure to environmental carcinogens in vivo induces neoplasia-related hallmarks in low-genotoxicity events, even after removal of insult

(2018) Marta Martins et al.   Scientific Reports

Tolerance to paternal genotoxic damage promotes survival during embryo development in zebrafish ( Danio rerio )

(2018) Cristina Fernández-Díez et al.   Biology Open

Distribution of DNA damage in the sperm nucleus: A study of zebrafish as a model of histone-packaged chromatin

(2018) S. González-Rojo et al.   THERIOGENOLOGY

Risks, Release and Concentrations of Engineered Nanomaterial in the Environment

(2018) Bernd Giese et al.   Scientific Reports

Synthesis of biogenic silver nanoparticles using Althaea officinalis as reducing agent: evaluation of toxicity and ecotoxicity

(2018) Diogo Torres Rheder et al.   Scientific Reports

Carcinogens and DNA damage

(2018) Jessica L. Barnes et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Modulation of DNA Repair Systems in Blind Cavefish during Evolution in Constant Darkness

(2018) Haiyu Zhao et al.   CURRENT BIOLOGY

In vitro and in vivo genotoxicity of oxygenated polycyclic aromatic hydrocarbons

(2018) Sarah McCarrick et al.   ENVIRONMENTAL POLLUTION

Gold nanorods induce early embryonic developmental delay and lethality in zebrafish (Danio rerio)

(2017) Bárbara Mesquita et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Loss of the homologous recombination generad51leads to Fanconi anemia-like symptoms in zebrafish

(2017) Jan Gregor Botthof et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uranium mining wastes: The use of the Fish Embryo Acute Toxicity Test (FET) test to evaluate toxicity and risk of environmental discharge

(2017) J. Lourenço et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Assessment of urban stream sediment pollutants entering estuaries using chemical analysis and multiple bioassays to characterise biological activities

(2017) Svenja Boehler et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cytotoxicity and genotoxicity of anticancer drug residues and their mixtures in experimental model with zebrafish liver cells

(2017) Matjaž Novak et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Embryotoxic and genotoxic effects of sewage effluents in zebrafish embryo using multiple endpoint testing

(2017) Sanja Babić et al.   WATER RESEARCH

Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm

(2017) Jeroen Vierstraete et al.   Scientific Reports

17α-ethynilestradiol and tributyltin mixtures modulates the expression of NER and p53 DNA repair pathways in male zebrafish gonads and disrupt offspring embryonic development

(2017) Joana Soares et al.   ECOLOGICAL INDICATORS

Deep challenges for China's war on water pollution

(2016) Dongmei Han et al.   ENVIRONMENTAL POLLUTION

Generation ofmt:egfptransgenic zebrafish biosensor for the detection of aquatic zinc and cadmium

(2016) Lili Liu et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Ecotoxicological assessment of glyphosate-based herbicides: Effects on different organisms

(2016) Laís de Brito Rodrigues et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Transcription Factors and DNA Repair Enzymes Compete for Damaged Promoter Sites

(2016) Stephen P. G. Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo DNA mismatch repair measurement in zebrafish embryos and its use in screening of environmental carcinogens

(2016) Yuanhong Chen et al.   JOURNAL OF HAZARDOUS MATERIALS

Histological and genotoxic evaluation of gold nanoparticles in ovarian cells of zebrafish (Danio rerio)

(2016) Navami Dayal et al.   JOURNAL OF NANOPARTICLE RESEARCH

Genotoxicity and oxidative stress induced by the fungicide azoxystrobin in zebrafish (Danio rerio) livers

(2016) Yingnan Han et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Genotoxic Effect and Carcinogenic Potential of a Mixture of As and Cd in Zebrafish at Permissible Maximum Contamination Levels for Drinking Water

(2016) Oguzhan Doganlar et al.   WATER AIR AND SOIL POLLUTION

Zebrafish in Brazilian Science: Scientific Production, Impact, and Collaboration

(2016) Ediane Maria Gheno et al.   Zebrafish

DNA Damage Assessment in Zebrafish Embryos Exposed to Monceren® 250 SC Fungicide Using the Alkaline Comet Assay

(2016) Marco Ku-Centurión et al.   Zebrafish

Norbornene derived nanocarrier reduces isoniazid mediated liver toxicity: assessment in HepG2 cell line and zebrafish model

(2016) Thangam Anju et al.   RSC Advances

Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development

(2016) Summer B. Thyme et al.   Cell Reports

Toward understanding the impacts of sediment contamination on a native fish species: transcriptional effects, EROD activity, and biliary PAH metabolites

(2016) Sven Koglin et al.   Environmental Sciences Europe

Interspecies variation in DNA damage induced by pollution

(2016) Claudia Sebbio et al.   Current Zoology

Zebrafish biosensor for toxicant induced muscle hyperactivity

(2016) Maryam Shahid et al.   Scientific Reports

Zebrafish genome instability after exposure to model genotoxicants

(2015) Maja Šrut et al.   ECOTOXICOLOGY

Proposal to optimize ecotoxicological evaluation of wastewater treated by conventional biological and ozonation processes

(2015) Adriana Wigh et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Genomic and gene expression responses to genotoxic stress in PAC2 zebrafish embryonic cell line

(2015) Maja Šrut et al.   JOURNAL OF APPLIED TOXICOLOGY

Generation of Tg(cyp1a:gfp) Transgenic Zebrafish for Development of a Convenient and Sensitive In Vivo Assay for Aryl Hydrocarbon Receptor Activity

(2015) Hongyan Xu et al.   MARINE BIOTECHNOLOGY

Assessment of toxicity and genotoxicity of low doses of 5-fluorouracil in zebrafish ( Danio rerio ) two-generation study

(2015) Róbert Kovács et al.   WATER RESEARCH

A review on emerging contaminants in wastewaters and the environment: Current knowledge, understudied areas and recommendations for future monitoring

(2015) Bruce Petrie et al.   WATER RESEARCH

Overview of Emerging Contaminants and Associated Human Health Effects

(2015) Meng Lei et al.   Biomed Research International

The Comet Assay and its applications in the field of ecotoxicology: a mature tool that continues to expand its perspectives

(2015) Joaquín de Lapuente et al.   Frontiers in Genetics

Genome Editing and Its Applications in Model Organisms

(2015) Dongyuan Ma et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Effects of depleted uranium on the reproductive success and F1 generation survival of zebrafish (Danio rerio)

(2014) Stéphanie Bourrachot et al.   AQUATIC TOXICOLOGY

Chronic dietary exposure of zebrafish to PAH mixtures results in carcinogenic but not genotoxic effects

(2014) T. Larcher et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Genotoxic and teratogenic effect of freshwater sediment samples from the Rhine and Elbe River (Germany) in zebrafish embryo using a multi-endpoint testing strategy

(2014) M. Garcia-Käufer et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Impact of gold nanoparticles on zebrafish exposed to a spiked sediment

(2014) Amina Dedeh et al.   Nanotoxicology

Zebrafish as an In Vivo High-Throughput Model for Genotoxicity

(2014) Sridhara Chakravarthy et al.   Zebrafish

Bisphenol A affects axonal growth, musculature and motor behavior in developing zebrafish

(2013) Xuechun Wang et al.   AQUATIC TOXICOLOGY

DNA repair activity in fish and interest in ecotoxicology: A review

(2013) Aude Kienzler et al.   AQUATIC TOXICOLOGY

The essential comet assay: a comprehensive guide to measuring DNA damage and repair

(2013) Amaya Azqueta et al.   ARCHIVES OF TOXICOLOGY

The effects of endosulfan on cytochrome P450 enzymes and glutathione S-transferases in zebrafish (Danio rerio) livers

(2013) Miao Dong et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Zebrafish as a model system to study toxicology

(2013) Yu-Jie Dai et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

8-Oxoguanine DNA glycosylase 1 (ogg1) maintains the function of cardiac progenitor cells during heart formation in zebrafish

(2013) Lifeng Yan et al.   EXPERIMENTAL CELL RESEARCH

A large-scale zebrafish gene knockout resource for the genome-wide study of gene function

(2013) G. K. Varshney et al.   GENOME RESEARCH

Changes in expression profiles of genes associated with DNA repair following induction of DNA damage in larval zebrafish Danio rerio

(2013) Helena C. Reinardy et al.   MUTAGENESIS

Non-mammalian vertebrate embryos as models in nanomedicine

(2013) Martina Giannaccini et al.   Nanomedicine-Nanotechnology Biology and Medicine

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Cadmium sulfate and CdTe-quantum dots alter DNA repair in zebrafish (Danio rerio) liver cells

(2013) Song Tang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A method for the assessment of DNA damage in individual, one day old, zebrafish embryo (Danio rerio), without prior cell isolation

(2013) Tina Eleršek et al.   TOXICOLOGY IN VITRO

Mapping of Zebrafish Research: A Global Outlook

(2013) Priyamvadah Kinth et al.   Zebrafish

DNA Repair by Reversal of DNA Damage

(2013) C. Yi et al.   Cold Spring Harbor Perspectives in Biology

Cobalt-induced genotoxicity in male zebrafish (Danio rerio), with implications for reproduction and expression of DNA repair genes

(2012) Helena C. Reinardy et al.   AQUATIC TOXICOLOGY

Zebrafish as a model system to study DNA damage and repair

(2012) De-Sheng Pei et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Comparative genotoxicity of aluminium and cadmium in embryonic zebrafish cells

(2012) Sandrine Pereira et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Genotoxicity of uranium contamination in embryonic zebrafish cells

(2011) Sandrine Pereira et al.   AQUATIC TOXICOLOGY

Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin

(2011) Lucia Rocco et al.   ENVIRONMENTAL TOXICOLOGY

Genotoxicity of acute and chronic gamma-irradiation on zebrafish cells and consequences for embryo development

(2011) Sandrine Pereira et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

The Light Responsive Transcriptome of the Zebrafish: Function and Regulation

(2011) Benjamin D. Weger et al.   PLoS One

Genotoxicity of platinum in embryos of zebrafish (Danio rerio) and ramshorn snail (Marisa cornuarietis)

(2011) Raphaela Osterauer et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Mechanisms of toxicity of di(2-ethylhexyl) phthalate on the reproductive health of male zebrafish

(2010) Tamsyn M. Uren-Webster et al.   AQUATIC TOXICOLOGY

Biomarkers as a tool to assess effects of chromium (VI): Comparison of responses in zebrafish early life stages and adults

(2010) Inês Domingues et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Zebrafish as a Model for the Study of the Phase II Cytosolic Sulfotransferases

(2010) Tzu-An Liu et al.   CURRENT DRUG METABOLISM

DNA mismatch repair and infertility

(2010) Sarmistha Mukherjee et al.   CURRENT OPINION IN UROLOGY

DNA damage and effects on glutathione-S-transferase activity induced by atrazine exposure in zebrafish (Danio rerio)

(2010) Lusheng Zhu et al.   ENVIRONMENTAL TOXICOLOGY

Genotoxicity assessment of two vineyard pesticides in zebrafish

(2010) Sylvie Bony et al.   INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY

Zebrafish Have a Competent p53-Dependent Nucleotide Excision Repair Pathway to Resolve Ultraviolet B–Induced DNA Damage in the Skin

(2010) Zhiqiang Zeng et al.   Zebrafish

Zebrafish Models of p53 Functions

(2010) N. Y. Storer et al.   Cold Spring Harbor Perspectives in Biology

Base Excision Repair in Early Zebrafish Development: Evidence for DNA Polymerase Switching and Standby AP Endonuclease Activity

(2009) Sean Fortier et al.   BIOCHEMISTRY

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Completion of meiosis in male zebrafish (Danio rerio) despite lack of DNA mismatch repair gene mlh1

(2008) Marcelo C. Leal et al.   CELL AND TISSUE RESEARCH

Is the fish embryo toxicity test (FET) with the zebrafish (Danio rerio) a potential alternative for the fish acute toxicity test?

(2008) E. Lammer et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Single-cell gel electrophoresis (the comet assay): Loops or fragments?

(2008) Sergey A. Shaposhnikov et al.   ELECTROPHORESIS

Modulation of steroidogenesis and xenobiotic biotransformation responses in zebrafish (Danio rerio) exposed to water-soluble fraction of crude oil

(2008) Augustine Arukwe et al.   ENVIRONMENTAL RESEARCH

The Comet assay for the evaluation of genotoxic impact in aquatic environments

(2008) G FRENZILLI et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Time-course Expression of DNA Repair-related Genes in Hepatocytes of Zebrafish (Danio rerio) After UV-B Exposure

(2008) Juliana Z. Sandrini et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

DNA damage induced by genotoxicants in zebrafish (Danio rerio) embryos after contact exposure to freeze-dried sediment and sediment extracts from Laguna Lake (The Philippines) as measured by the comet assay

(2007) Thomas Kosmehl et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS