The activity of methacrylate esters in skin sensitisation test methods II. A review of complementary and additional analyses

α-Sens: The improved ARE-Nrf2-based sensitization screening assay using normalized transcriptional activity

(2020) Yosuke Maeda et al.   TOXICOLOGY

The activity of methacrylate esters in skin sensitisation test methods: A review

(2019) Ian Kimber   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Evaluation of skin sensitization potential of chemicals by local lymph node assay using 5-bromo-2-deoxyuridine with flow cytometry

(2019) Byeol-I. Han et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Non-animal methods to predict skin sensitization (II): an assessment of defined approaches

(2018) Nicole C. Kleinstreuer et al.   CRITICAL REVIEWS IN TOXICOLOGY

Toxicological assessment of lower alkyl methacrylate esters by a category approach

(2018) Heinz-Peter Gelbke et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

An evaluation of selected (Q)SARs/expert systems for predicting skin sensitisation potential

(2018) J. M. Fitzpatrick et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Skin and respiratory chemical allergy: confluence and divergence in a hybrid adverse outcome pathway

(2018) Ian Kimber et al.   Toxicology Research

Non-animal assessment of skin sensitization hazard: Is an integrated testing strategy needed, and if so what should be integrated?

(2017) David W. Roberts et al.   JOURNAL OF APPLIED TOXICOLOGY

An improvement of LLNA:DA to assess the skin sensitization potential of chemicals

(2017) Hongwei Zhang et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Quantitative risk assessment for skin sensitization: Success or failure?

(2017) Ian Kimber et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Prediction of skin sensitization potency sub-categories using peptide reactivity data

(2017) Britta Wareing et al.   TOXICOLOGY IN VITRO

An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens

(2017) Kazutoshi Saito et al.   TOXICOLOGY IN VITRO

State of the art in non-animal approaches for skin sensitization testing: from individual test methods towards testing strategies

(2016) Janine Ezendam et al.   ARCHIVES OF TOXICOLOGY

Integrated decision strategies for skin sensitization hazard

(2016) Judy Strickland et al.   JOURNAL OF APPLIED TOXICOLOGY

Performance standard-based validation study for local lymph node assay: 5-bromo-2-deoxyuridine-flow cytometry method

(2016) Ilyoung Ahn et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Skin sensitization quantitative risk assessment: A review of underlying assumptions

(2016) David Basketter et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Predicting skin sensitisation using a decision tree integrated testing strategy with an in silico model and in chemico/in vitro assays

(2016) Donna S. Macmillan et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Peptide reactivity associated with skin sensitization: The QSAR Toolbox and TIMES compared to the DPRA

(2016) D. Urbisch et al.   TOXICOLOGY IN VITRO

Consensus of classification trees for skin sensitisation hazard prediction

(2016) D. Asturiol et al.   TOXICOLOGY IN VITRO

SENS-IS, a 3D reconstituted epidermis based model for quantifying chemical sensitization potency: Reproducibility and predictivity results from an inter-laboratory study

(2016) Françoise Cottrez et al.   TOXICOLOGY IN VITRO

Mechanism-Based QSAR Modeling of Skin Sensitization

(2015) J. C. Dearden et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Immunological mechanisms in allergic contact dermatitis

(2015) Stefan F. Martin   Current Opinion in Allergy and Clinical Immunology

Anin vitrohuman skin test for assessing sensitization potential

(2015) S. S. Ahmed et al.   JOURNAL OF APPLIED TOXICOLOGY

A novelin chemicomethod to detect skin sensitizers in highly diluted reaction conditions

(2015) Yusuke Yamamoto et al.   JOURNAL OF APPLIED TOXICOLOGY

Prospective multicentre study of the U-SENS test method for skin sensitization testing

(2015) N. Alépée et al.   TOXICOLOGY IN VITRO

Optimization of the IL-8 Luc assay as an in vitro test for skin sensitization

(2015) Yutaka Kimura et al.   TOXICOLOGY IN VITRO

The Myeloid U937 Skin Sensitization Test (U-SENS) addresses the activation of dendritic cell event in the adverse outcome pathway for skin sensitization

(2015) Cécile Piroird et al.   TOXICOLOGY IN VITRO

Systematic evaluation of non-animal test methods for skin sensitisation safety assessment

(2015) Kerstin Reisinger et al.   TOXICOLOGY IN VITRO

The Local Lymph Node Assay in 2014

(2014) David A. Basketter et al.   Dermatitis

Assessment of the skin sensitising potency of the lower alkyl methacrylate esters

(2014) Ian Kimber et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

TIMES-SS – Recent refinements resulting from an industrial skin sensitisation consortium

(2014) G. Patlewicz et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

LuSens: A keratinocyte based ARE reporter gene assay for use in integrated testing strategies for skin sensitization hazard identification

(2014) Tzutzuy Ramirez et al.   TOXICOLOGY IN VITRO

From pathways to people: applying the adverse outcome pathway (AOP) for skin sensitization to risk assessment

(2014) Cameron MacKay   ALTEX-Alternatives to Animal Experimentation

Development of a new in vitro skin sensitization assay (Epidermal Sensitization Assay; EpiSensA) using reconstructed human epidermis

(2013) Kazutoshi Saito et al.   TOXICOLOGY IN VITRO

Danger, intracellular signaling, and the orchestration of dendritic cell function in skin sensitization

(2012) Joseph S. Ainscough et al.   Journal of Immunotoxicology

Putting the parts together: Combining in vitro methods to test for skin sensitizing potentials

(2012) Caroline Bauch et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency

(2012) Yuko Nukada et al.   TOXICOLOGY IN VITRO

Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010

(2011) Sarah Adler et al.   ARCHIVES OF TOXICOLOGY

Methyl methacrylate and respiratory sensitization: A Critical review

(2011) Jonathan Borak et al.   CRITICAL REVIEWS IN TOXICOLOGY

Experience with local lymph node assay performance standards using standard radioactivity and nonradioactive cell count measurements

(2011) David Basketter et al.   JOURNAL OF APPLIED TOXICOLOGY

An In Vitro Test to Screen Skin Sensitizers Using a Stable THP-1–Derived IL-8 Reporter Cell Line, THP-G8

(2011) Toshiya Takahashi et al.   TOXICOLOGICAL SCIENCES

Chemical Allergy: Translating Biology into Hazard Characterization

(2010) I. Kimber et al.   TOXICOLOGICAL SCIENCES

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro

(2010) Roger Emter et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Potency values from the local lymph node assay: Application to classification, labelling and risk assessment

(2009) S.E. Loveless et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

HMOX1 and NQO1 Genes are Upregulated in Response to Contact Sensitizers in Dendritic Cells and THP-1 Cell Line: Role of the Keap1/Nrf2 Pathway

(2008) Nadège Ade et al.   TOXICOLOGICAL SCIENCES