DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

(2012) Katharina Schlacher et al.   CANCER CELL

Human Nuclease/Helicase DNA2 Alleviates Replication Stress by Promoting DNA End Resection

(2012) G. Peng et al.   CANCER RESEARCH

The Intra-S Phase Checkpoint Targets Dna2 to Prevent Stalled Replication Forks from Reversing

(2012) Jiazhi Hu et al.   CELL

Okazaki Fragment Processing-independent Role for Human Dna2 Enzyme during DNA Replication

(2012) Julien P. Duxin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preventing Replication Stress to Maintain Genome Stability: Resolving Conflicts between Replication and Transcription

(2012) Rodrigo Bermejo et al.   MOLECULAR CELL

Regulation of DNA-End Resection by hnRNPU-like Proteins Promotes DNA Double-Strand Break Signaling and Repair

(2012) Sophie E. Polo et al.   MOLECULAR CELL

Double-Strand Break End Resection and Repair Pathway Choice

(2011) Lorraine S. Symington et al.   Annual Review of Genetics

Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11

(2011) Katharina Schlacher et al.   CELL

Rescue of replication failure by Fanconi anaemia proteins

(2011) Angelos Constantinou   CHROMOSOMA

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

(2011) A. V. Nimonkar et al.   GENES & DEVELOPMENT

Correct End Use during End Joining of Multiple Chromosomal Double Strand Breaks Is Influenced by Repair Protein RAD50, DNA-dependent Protein Kinase DNA-PKcs, and Transcription Context

(2011) Amanda Gunn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks

(2011) Yoshitami Hashimoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA-PK-Dependent RPA2 Hyperphosphorylation Facilitates DNA Repair and Suppresses Sister Chromatid Exchange

(2011) Hungjiun Liaw et al.   PLoS One

Mechanism of RAD51-Dependent DNA Interstrand Cross-Link Repair

(2011) D. T. Long et al.   SCIENCE

Common fragile sites: mechanisms of instability revisited

(2011) Michelle Debatisse et al.   TRENDS IN GENETICS

The role of RPA2 phosphorylation in homologous recombination in response to replication arrest

(2010) Wei Shi et al.   CARCINOGENESIS

A novel role for fanconi anemia (FA) pathway effector protein FANCD2 in cell cycle progression of untransformed primary human cells

(2010) Ihn Young Song et al.   CELL CYCLE

Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate

(2010) Teodora Nikolova et al.   DNA REPAIR

DNA end resection by CtIP and exonuclease 1 prevents genomic instability

(2010) Wassim Eid et al.   EMBO REPORTS

A Genome-wide Camptothecin Sensitivity Screen Identifies a Mammalian MMS22L-NFKBIL2 Complex Required for Genomic Stability

(2010) Brenda C. O'Connell et al.   MOLECULAR CELL

Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of Fanconi Anemia

(2010) Adele Adamo et al.   MOLECULAR CELL

Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis

(2010) Yoshitami Hashimoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

How the Fanconi Anemia Pathway Guards the Genome

(2009) George-Lucian Moldovan et al.   Annual Review of Genetics

TheMPH1Gene ofSaccharomyces cerevisiaeFunctions in Okazaki Fragment Processing

(2009) Young-Hoon Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress

(2009) V. M. Vassin et al.   JOURNAL OF CELL SCIENCE

Human Dna2 Is a Nuclear and Mitochondrial DNA Maintenance Protein

(2009) J. P. Duxin et al.   MOLECULAR AND CELLULAR BIOLOGY

Checkpoint Signaling from a Single DNA Interstrand Crosslink

(2009) Merav Ben-Yehoyada et al.   MOLECULAR CELL

Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks

(2009) Bunsyo Shiotani et al.   MOLECULAR CELL

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle

(2009) Maximina H. Yun et al.   NATURE

The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair

(2009) P. Knipscheer et al.   SCIENCE

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

(2008) Zhu Zhu et al.   CELL

Mechanism of Replication-Coupled DNA Interstrand Crosslink Repair

(2008) Markus Räschle et al.   CELL

Flap Endonuclease 1 Contributes to Telomere Stability

(2008) Abhishek Saharia et al.   CURRENT BIOLOGY

DNA helicases Sgs1 and BLM promote DNA double-strand break resection

(2008) S. Gravel et al.   GENES & DEVELOPMENT

Human DNA2 Is a Mitochondrial Nuclease/Helicase for Efficient Processing of DNA Replication and Repair Intermediates

(2008) Li Zheng et al.   MOLECULAR CELL

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

(2008) A. V. Nimonkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA