MazF toxin causes alterations in Staphylococcus aureus transcriptome, translatome and proteome that underlie bacterial dormancy

Type II toxin-antitoxin systems: evolution and revolutions

(2020) N. Fraikin et al.   JOURNAL OF BACTERIOLOGY

YjbH Solubility Controls Spx in Staphylococcus aureus: Implication for MazEF Toxin-Antitoxin System Regulation

(2020) Olesya O. Panasenko et al.   Frontiers in Microbiology

The hibernating 100S complex is a target of ribosome-recycling factor and elongation factor G in Staphylococcus aureus

(2020) Arnab Basu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular Staphylococcus aureus persisters upon antibiotic exposure

(2020) Frédéric Peyrusson et al.   Nature Communications

Stress Can Induce Transcription of Toxin-Antitoxin Systems without Activating Toxin

(2020) Michele LeRoux et al.   MOLECULAR CELL

Insights into the global effect on Staphylococcus aureus growth arrest by induction of the endoribonuclease MazF toxin

(2020) Roberto Sierra et al.   NUCLEIC ACIDS RESEARCH

Definitions and guidelines for research on antibiotic persistence

(2019) Nathalie Q. Balaban et al.   NATURE REVIEWS MICROBIOLOGY

The Staphylococcal Cell Wall

(2019) Rita Sobral et al.   Microbiology Spectrum

The Toxin-Antitoxin MazEF Drives Staphylococcus aureus Biofilm Formation, Antibiotic Tolerance, and Chronic Infection

(2019) Dongzhu Ma et al.   mBio

Mycobacterial HflX is a ribosome splitting factor that mediates antibiotic resistance

(2019) Paulami Rudra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Analysis of the E. coli Toxin MazF Reveals Widespread Cleavage of mRNA and the Inhibition of rRNA Maturation and Ribosome Biogenesis

(2018) Peter H. Culviner et al.   MOLECULAR CELL

Linking toxin-antitoxin systems with phenotypes: A Staphylococcus aureus viewpoint

(2018) Roberto Sierra et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Antibiotic resistance: a rundown of a global crisis

(2018) Bilal Aslam et al.   Infection and Drug Resistance

Transcriptome-wide measurement of translation by ribosome profiling

(2017) Nicholas J. McGlincy et al.   METHODS

Disassembly of theStaphylococcus aureushibernating 100S ribosome by an evolutionarily conserved GTPase

(2017) Arnab Basu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Ribosome Rescue in Bacteria

(2017) Paul Huter et al.   TRENDS IN BIOCHEMICAL SCIENCES

Toxins of Prokaryotic Toxin-Antitoxin Systems with Sequence-Specific Endoribonuclease Activity

(2017) Hisako Masuda et al.   Toxins

Prokaryotic toxin–antitoxin systems: novel regulations of the toxins

(2016) Yuichi Otsuka   CURRENT GENETICS

Ribosome hibernation factor promotesStaphylococcalsurvival and differentially represses translation

(2016) Arnab Basu et al.   NUCLEIC ACIDS RESEARCH

The MazF-regulon: a toolbox for the post-transcriptional stress response inEscherichia coli

(2016) Martina Sauert et al.   NUCLEIC ACIDS RESEARCH

Genome-wide assessment of differential translations with ribosome profiling data

(2016) Zhengtao Xiao et al.   Nature Communications

Toxin-Antitoxin Systems of Staphylococcus aureus

(2016) Christopher Schuster et al.   Toxins

Ribosome profiling reveals the what, when, where and how of protein synthesis

(2015) Gloria A. Brar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA Futile Cycling in Model Persisters Derived from MazF Accumulation

(2015) W. W. K. Mok et al.   mBio

Transposon Mutagenesis Identifies Novel Genes Associated with Staphylococcus aureus Persister Formation

(2015) Wenjie Wang et al.   Frontiers in Microbiology

The MazEF Toxin-Antitoxin System Alters the β-Lactam Susceptibility of Staphylococcus aureus

(2015) Christopher F. Schuster et al.   PLoS One

Role of Adaptor TrfA and ClpPC in Controlling Levels of SsrA-Tagged Proteins and Antitoxins in Staphylococcus aureus

(2014) N. P. Donegan et al.   JOURNAL OF BACTERIOLOGY

Regulated protein aggregation: a mechanism to control the activity of the ClpXP adaptor protein YjbH

(2014) Jakob Engman et al.   MOLECULAR MICROBIOLOGY

Ribosome profiling: new views of translation, from single codons to genome scale

(2014) Nicholas T. Ingolia   NATURE REVIEWS GENETICS

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

(2014) Charity W Law et al.   GENOME BIOLOGY

Detection of endogenous MazF enzymatic activity in Staphylococcus aureus

(2013) Julia J. van Rensburg et al.   ANALYTICAL BIOCHEMISTRY

Wall Teichoic Acids of Gram-Positive Bacteria

(2013) Stephanie Brown et al.   Annual Review of Microbiology

The Staphylococcus aureus Thiol/Oxidative Stress Global Regulator Spx ControlstrfA, a Gene Implicated in Cell Wall Antibiotic Resistance

(2013) Ambre Jousselin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bacterial Persister Cell Formation and Dormancy

(2013) Thomas K. Wood et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Normalcy of Dormancy: Common Themes in Microbial Quiescence

(2013) Emily S.C. Rittershaus et al.   Cell Host & Microbe

MazF-induced Growth Inhibition and Persister Generation inEscherichia coli

(2013) Arti Tripathi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Perspective of Peptidoglycan Biosynthesis and Assembly

(2012) Andrew L. Lovering et al.   Annual Review of Biochemistry

Decoding in the Absence of a Codon by tmRNA and SmpB in the Ribosome

(2012) C. Neubauer et al.   SCIENCE

Toxin-Antitoxin Systems in Bacteria and Archaea

(2011) Yoshihiro Yamaguchi et al.   Annual Review of Genetics

Selective Translation of Leaderless mRNAs by Specialized Ribosomes Generated by MazF in Escherichia coli

(2011) Oliver Vesper et al.   CELL

The YjbH Adaptor Protein Enhances Proteolysis of the Transcriptional Regulator Spx in Staphylococcus aureus

(2011) J. Engman et al.   JOURNAL OF BACTERIOLOGY

Vectors for improved Tet repressor-dependent gradual gene induction or silencing in Staphylococcus aureus

(2011) L. Helle et al.   MICROBIOLOGY-SGM

Determinants of translation efficiency and accuracy

(2011) H. Gingold et al.   Molecular Systems Biology

Whole Genome Sequencing and Complete Genetic Analysis Reveals Novel Pathways to Glycopeptide Resistance in Staphylococcus aureus

(2011) Adriana Renzoni et al.   PLoS One

Persister Cells

(2010) Kim Lewis   Annual Review of Microbiology

Repair of Global Regulators in Staphylococcus aureus 8325 and Comparative Analysis with Other Clinical Isolates

(2010) S. Herbert et al.   INFECTION AND IMMUNITY

Wall Teichoic Acid Function, Biosynthesis, and Inhibition

(2009) Jonathan G. Swoboda et al.   CHEMBIOCHEM

Formation of 100S ribosomes inStaphylococcus aureusby the hibernation promoting factor homologSaHPF

(2009) Masami Ueta et al.   GENES TO CELLS

Staphylococcus aureus MazF Specifically Cleaves a Pentad Sequence, UACAU, Which Is Unusually Abundant in the mRNA for Pathogenic Adhesive Factor SraP

(2009) L. Zhu et al.   JOURNAL OF BACTERIOLOGY

Regulation of the mazEF Toxin-Antitoxin Module in Staphylococcus aureus and Its Impact on sigB Expression

(2009) N. P. Donegan et al.   JOURNAL OF BACTERIOLOGY

Overexpression of MazFSa in Staphylococcus aureus Induces Bacteriostasis by Selectively Targeting mRNAs for Cleavage

(2009) Z. Fu et al.   JOURNAL OF BACTERIOLOGY

Proteolytic Regulation of Toxin-Antitoxin Systems by ClpPC in Staphylococcus aureus

(2009) N. P. Donegan et al.   JOURNAL OF BACTERIOLOGY

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Escherichia coli MazF Leads to the Simultaneous Selective Synthesis of Both “Death Proteins” and “Survival Proteins”

(2009) Shahar Amitai et al.   PLoS Genetics

Identification by Genomic and Genetic Analysis of Two New Genes Playing a Key Role in Intermediate Glycopeptide Resistance in Staphylococcus aureus

(2008) A. Renzoni et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY