Modulatory profiling identifies mechanisms of small molecule-induced cell death

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Discovery of drug mode of action and drug repositioning from transcriptional responses

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Autophagic Components Contribute to Hypersensitive Cell Death in Arabidopsis

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Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

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Predicting new molecular targets for known drugs

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Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds

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RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

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Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

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Mitochondrial Protein Targets of Thiol-Reactive Electrophiles

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Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells

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Variations in DNA elucidate molecular networks that cause disease

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Identification of RIP1 kinase as a specific cellular target of necrostatins

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Small-molecule aggregates inhibit amyloid polymerization

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Caspase-independent cell death: leaving the set without the final cut

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Drug Target Identification Using Side-Effect Similarity

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Apoptosis: controlled demolition at the cellular level

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