Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent

Published 2017 View Full Article

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Title
Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent
Authors
Keywords
CRISPRi, CRISPRa, chemical genetics, genome-wide CRISPR screening, drug target identification, drug mechanism of action, rigosertib, microtubules
Journal
MOLECULAR CELL
Volume 68, Issue 1, Pages 210-223.e6
Publisher
Elsevier BV
Online
2017-10-11
DOI
10.1016/j.molcel.2017.09.012

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