What NIR photodynamic activation offers molecular targeted nanomedicines: Perspectives into the conundrum of tumor specificity and selectivity

Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

(2020) Yi-Hsien Cheng et al.   ACS Nano

Size-Transformable Hyaluronan Stacked Self-Assembling Peptide Nanoparticles for Improved Transcellular Tumor Penetration and Photo–Chemo Combination Therapy

(2020) Zhaoqing Cong et al.   ACS Nano

EGFR targeted nanobody functionalized polymeric micelles loaded with mTHPC for selective photodynamic therapy

(2020) Yanna Liu et al.   MOLECULAR PHARMACEUTICS

The entry of nanoparticles into solid tumours

(2020) Shrey Sindhwani et al.   NATURE MATERIALS

Cell Membrane Coated-Biomimetic Nanoplatforms Toward Cancer Theranostics

(2020) Tingting Li et al.   Frontiers in Bioengineering and Biotechnology

NIR Photodynamic Destruction of PDAC and HNSCC Nodules Using Triple-Receptor-Targeted Photoimmuno-Nanoconjugates: Targeting Heterogeneity in Cancer

(2020) Shazia Bano et al.   Journal of Clinical Medicine

Dual‐agent fluorescent labeling of soft‐tissue sarcomas improves the contrast based upon targeting both interstitial and cellular components of the tumor milieu

(2020) Hira S. Sardar et al.   JOURNAL OF SURGICAL ONCOLOGY

Cell Membrane-Covered Nanoparticles as Biomaterials

(2019) Mingjun Xuan et al.   National Science Review

Photodynamic Therapy with Liposomes Encapsulating Photosensitizers with Aggregation-Induced Emission

(2019) Yang Yang et al.   NANO LETTERS

Organic Semiconducting Pro-nanostimulants for Near-Infrared Photoactivatable Cancer Immunotherapy

(2019) Jingchao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices

(2019) Hongqian Chu et al.   Nature Communications

A regimen to minimize pain during blue light photodynamic therapy of actinic keratoses: Bilaterally controlled, randomized trial of simultaneous versus conventional illumination

(2019) Urvashi Kaw et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Impacting Pancreatic Cancer Therapy in Heterotypic in Vitro Organoids and in Vivo Tumors with Specificity-Tuned, NIR-Activable Photoimmunonanoconjugates: Towards Conquering Desmoplasia?

(2019) Girgis Obaid et al.   NANO LETTERS

Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy

(2019) Else Driehuis et al.   Journal of Clinical Medicine

Prostate-Specific Membrane Antigen Targeted Gold Nanoparticles for Theranostics of Prostate Cancer

(2018) Joey Dacula Mangadlao et al.   ACS Nano

Light-Activatable Red Blood Cell Membrane-Camouflaged Dimeric Prodrug Nanoparticles for Synergistic Photodynamic/Chemotherapy

(2018) Qing Pei et al.   ACS Nano

Quantifying the Ligand-Coated Nanoparticle Delivery to Cancer Cells in Solid Tumours

(2018) Qin Dai et al.   ACS Nano

Folate-modified PLGA nanoparticles for tumor-targeted delivery of pheophorbide a in vivo

(2018) Jihwan Son et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Enhanced Cellular Ablation by Attenuating Hypoxia Status and Reprogramming Tumor-Associated Macrophages via NIR Light-Responsive Upconversion Nanocrystals

(2018) Xiangzhao Ai et al.   BIOCONJUGATE CHEMISTRY

Overcoming obstacles in the tumor microenvironment: Recent advancements in nanoparticle delivery for cancer theranostics

(2018) Marta Overchuk et al.   BIOMATERIALS

First-in-human intraoperative near-infrared fluorescence imaging of glioblastoma using cetuximab-IRDye800

(2018) Sarah E. Miller et al.   JOURNAL OF NEURO-ONCOLOGY

Photodynamic activity of Temoporfin nanoparticles induces a shift to the M1-like phenotype in M2-polarized macrophages

(2018) Zhenxin Zhu et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Photodynamic therapy: Promoting in vitro efficacy of photodynamic therapy by liposomal formulations of a photosensitizing agent

(2018) Imran Rizvi et al.   LASERS IN SURGERY AND MEDICINE

Epidermal growth factor receptor (EGFR) density may not be the only determinant for the efficacy of EGFR-targeted photoimmunotherapy in human head and neck cancer cell lines

(2018) Wei Peng et al.   LASERS IN SURGERY AND MEDICINE

Recent Progress in Upconversion Photodynamic Therapy

(2018) Hailong Qiu et al.   Nanomaterials

Metal-Organic Framework Nanoshuttle for Synergistic Photodynamic and Low-Temperature Photothermal Therapy

(2018) Kai Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Nanolipid Formulations of Benzoporphyrin Derivative: Exploring the Dependence of Nanoconstruct Photophysics and Photochemistry on Their Therapeutic Index in Ovarian Cancer Cells

(2018) Girgis Obaid et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Aptamer-functionalized nanoscale metal-organic frameworks for targeted photodynamic therapy

(2018) Hong-Min Meng et al.   Theranostics

Phototheranostics: Active Targeting of Orthotopic Glioma Using Biomimetic Proteolipid Nanoparticles

(2018) Yali Jia et al.   ACS Nano

Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433

(2018) Susan Monro et al.   CHEMICAL REVIEWS

Reprogramming Tumor-Associated Macrophages by Nanoparticle-Based Reactive Oxygen Species Photogeneration

(2018) Changrong Shi et al.   NANO LETTERS

Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles

(2018) Parisa Foroozandeh et al.   Nanoscale Research Letters

A Combination of Visudyne and a Lipid-anchored Liposomal Formulation of Benzoporphyrin Derivative Enhances Photodynamic Therapy Efficacy in a 3D Model for Ovarian Cancer

(2018) Imran Rizvi et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Emerging Role of the Spleen in the Pharmacokinetics of Monoclonal Antibodies, Nanoparticles and Exosomes

(2017) Mauro Cataldi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mn2+-coordinated PDA@DOX/PLGA nanoparticles as a smart theranostic agent for synergistic chemo-photothermal tumor therapy

(2017) Juqun Xi et al.   International Journal of Nanomedicine

Activatable clinical fluorophore-quencher antibody pairs as dual molecular probes for the enhanced specificity of image-guided surgery

(2017) Girgis Obaid et al.   JOURNAL OF BIOMEDICAL OPTICS

Nanoparticles and innate immunity: new perspectives on host defence

(2017) Diana Boraschi et al.   SEMINARS IN IMMUNOLOGY

Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies

(2017) Jiayin Shen et al.   Oncotarget

Chemical Strategies for Enhancing Activity and Charge Transfer in Ultrathin Pt Nanowires Immobilized onto Nanotube Supports for the Oxygen Reduction Reaction

(2016) Luyao Li et al.   ACS Applied Materials & Interfaces

An O2Self-Sufficient Biomimetic Nanoplatform for Highly Specific and Efficient Photodynamic Therapy

(2016) Hong Cheng et al.   ADVANCED FUNCTIONAL MATERIALS

New photosensitizers for photodynamic therapy

(2016) H. Abrahamse et al.   BIOCHEMICAL JOURNAL

Comparing desferrioxamine and light fractionation enhancement of ALA-PpIX photodynamic therapy in skin cancer

(2016) Ana Luiza Ribeiro de Souza et al.   BRITISH JOURNAL OF CANCER

Two-photon excitation nanoparticles for photodynamic therapy

(2016) Yizhong Shen et al.   CHEMICAL SOCIETY REVIEWS

EGFR targeted nanobody–photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer

(2016) Pieter B.A.A. van Driel et al.   JOURNAL OF CONTROLLED RELEASE

Chlorin-Based Nanoscale Metal–Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy

(2016) Kuangda Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Retrospective 30 Years After Discovery of the Enhanced Permeability and Retention Effect of Solid Tumors: Next-Generation Chemotherapeutics and Photodynamic Therapy-Problems, Solutions, and Prospects

(2016) Hiroshi Maeda et al.   MICROCIRCULATION

Simultaneous delivery of cytotoxic and biologic therapeutics using nanophotoactivatable liposomes enhances treatment efficacy in a mouse model of pancreatic cancer

(2016) Shifalika Tangutoori et al.   Nanomedicine-Nanotechnology Biology and Medicine

Photonanomedicine: a convergence of photodynamic therapy and nanotechnology

(2016) Girgis Obaid et al.   Nanoscale

A photoactivable multi-inhibitor nanoliposome for tumour control and simultaneous inhibition of treatment escape pathways

(2016) Bryan Q. Spring et al.   Nature Nanotechnology

Erratum: Corrigendum: Surface modification of nanoparticles enables selective evasion of phagocytic clearance by distinct macrophage phenotypes

(2016) Yaqing Qie et al.   Scientific Reports

Sphingomyelin Liposomes Containing Porphyrin-phospholipid for Irinotecan Chemophototherapy

(2016) Kevin A Carter et al.   Theranostics

Beyond the Barriers of Light Penetration: Strategies, Perspectives and Possibilities for Photodynamic Therapy

(2016) Srivalleesha Mallidi et al.   Theranostics

Superparamagnetic Fe3O4-PEG2K-FA@Ce6 Nanoprobes for in Vivo Dual-mode Imaging and Targeted Photodynamic Therapy

(2016) Ting Yin et al.   Scientific Reports

Multipronged Design of Light-Triggered Nanoparticles To Overcome Cisplatin Resistance for Efficient Ablation of Resistant Tumor

(2015) Yanli Li et al.   ACS Nano

Physical Principles of Nanoparticle Cellular Endocytosis

(2015) Sulin Zhang et al.   ACS Nano

Light-Controlled Delivery of Monoclonal Antibodies for Targeted Photoinactivation of Ki-67

(2015) Sijia Wang et al.   MOLECULAR PHARMACEUTICS

Liposome-Based Engineering of Cells To Package Hydrophobic Compounds in Membrane Vesicles for Tumor Penetration

(2015) Junsung Lee et al.   NANO LETTERS

Blockade of oral tolerance to ovalbumin in mice by silver nanoparticles

(2015) Yingying Xu et al.   Nanomedicine

Breaking the depth dependency of phototherapy with Cerenkov radiation and low-radiance-responsive nanophotosensitizers

(2015) Nalinikanth Kotagiri et al.   Nature Nanotechnology

Cancer targeting with biomolecules: a comparative study of photodynamic therapy efficacy using antibody or lectin conjugated phthalocyanine-PEG gold nanoparticles

(2015) Girgis Obaid et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle

(2015) Miles A. Miller et al.   Science Translational Medicine

Prediction of Tumor Recurrence and Therapy Monitoring Using Ultrasound-Guided Photoacoustic Imaging

(2015) Srivalleesha Mallidi et al.   Theranostics

Targeted Iron-Oxide Nanoparticle for Photodynamic Therapy and Imaging of Head and Neck Cancer

(2014) Dongsheng Wang et al.   ACS Nano

Highly Biocompatible Carbon Nanodots for Simultaneous Bioimaging and Targeted Photodynamic Therapy In Vitro and In Vivo

(2014) Yuri Choi et al.   ADVANCED FUNCTIONAL MATERIALS

Optical properties of human colon tissues in the 350 – 2500 nm spectral range

(2014) A N Bashkatov et al.   QUANTUM ELECTRONICS

The Effect of Molecular Weight, PK, and Valency on Tumor Biodistribution and Efficacy of Antibody-Based Drugs

(2014) Ruth Muchekehu et al.   Translational Oncology

Porphyrin–phospholipid liposomes permeabilized by near-infrared light

(2014) Kevin A. Carter et al.   Nature Communications

Targeting-Triggered Porphysome Nanostructure Disruption for Activatable Photodynamic Therapy

(2014) Cheng S. Jin et al.   Advanced Healthcare Materials

NIR-Triggered Anticancer Drug Delivery by Upconverting Nanoparticles with Integrated Azobenzene-Modified Mesoporous Silica

(2013) Jianan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology

(2013) U. Prabhakar et al.   CANCER RESEARCH

Single-Antibody, Targeted Nanoparticle Delivery of Camptothecin

(2013) Han Han et al.   MOLECULAR PHARMACEUTICS

Folate-targeted PEGylated liposomes improve the selectivity of PDT with meta-tetra(hydroxyphenyl)chlorin (m-THPC)

(2013) Francesca Moret et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Penetration of Laser Light at 808 and 980 nm in Bovine Tissue Samples

(2013) Donald E. Hudson et al.   PHOTOMEDICINE AND LASER SURGERY

Optical properties of biological tissues: a review

(2013) Steven L Jacques   PHYSICS IN MEDICINE AND BIOLOGY

Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles

(2013) P. L. Rodriguez et al.   SCIENCE

In Vivo Targeted Deep-Tissue Photodynamic Therapy Based on Near-Infrared Light Triggered Upconversion Nanoconstruct

(2012) Sisi Cui et al.   ACS Nano

Targeting the Oncofetal Thomsen-Friedenreich Disaccharide Using Jacalin-PEG Phthalocyanine Gold Nanoparticles for Photodynamic Cancer Therapy

(2012) Girgis Obaid et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor-targeting hyaluronic acid nanoparticles for photodynamic imaging and therapy

(2012) Hong Yeol Yoon et al.   BIOMATERIALS

Superoxide Flashes Reveal Novel Properties of Mitochondrial Reactive Oxygen Species Excitability in Cardiomyocytes

(2012) Kaitao Li et al.   BIOPHYSICAL JOURNAL

Intracellular Signaling by Diffusion: Can Waves of Hydrogen Peroxide Transmit Intracellular Information in Plant Cells?

(2012) Christian Lyngby Vestergaard et al.   Frontiers in Plant Science

Mannose-Functionalized Mesoporous Silica Nanoparticles for Efficient Two-Photon Photodynamic Therapy of Solid Tumors

(2011) Magali Gary-Bobo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Do folate-receptor targeted liposomal photosensitizers enhance photodynamic therapy selectivity?

(2011) María García-Díaz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Photodynamic therapy of cancer: An update

(2011) Patrizia Agostinis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Macrophage scavenger receptor A mediates the uptake of gold colloids by macrophagesin vitro

(2011) Angela França et al.   Nanomedicine

Targeted photodynamic therapy of breast cancer cells using antibody–phthalocyanine–gold nanoparticle conjugates

(2011) Tanya Stuchinskaya et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization

(2010) Jonathan P. Celli et al.   CHEMICAL REVIEWS

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

A modeling analysis of the effects of molecular size and binding affinity on tumor targeting

(2009) M. M. Schmidt et al.   MOLECULAR CANCER THERAPEUTICS

Porphyrin and Nonporphyrin Photosensitizers in Oncology: Preclinical and Clinical Advances in Photodynamic Therapy

(2009) Aisling E. O’Connor et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Photophysics and photochemistry of photodynamic therapy: fundamental aspects

(2008) K. Plaetzer et al.   LASERS IN MEDICAL SCIENCE

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology