Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

(2019) Gitte Berkers et al.   Cell Reports

Mouse and human urothelial cancer organoids: A tool for bladder cancer research

(2019) Jasper Mullenders et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging of Tumor Spheroids, Dual-Isotope SPECT, and Autoradiographic Analysis to Assess the Tumor Uptake and Distribution of Different Nanobodies

(2019) Irati Beltrán Hernández et al.   MOLECULAR IMAGING AND BIOLOGY

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

(2019) Oded Kopper et al.   NATURE MEDICINE

Oral mucosal organoids as a potential platform for personalized cancer therapy

(2019) Else Driehuis et al.   Cancer Discovery

Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients

(2019) Salo N. Ooft et al.   Science Translational Medicine

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

(2018) Norman Sachs et al.   CELL

Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer

(2018) Suk Hyung Lee et al.   CELL

A Phase 2a, Multicenter, Open-Label Study of RM-1929 Photoimmunotherapy in Patients With Recurrent Head And Neck Cancer

(2018) D. Cognetti et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

(2018) Georgios Vlachogiannis et al.   SCIENCE

Organoid profiling identifies common responders to chemotherapy in pancreatic cancer

(2018) Hervé Tiriac et al.   Cancer Discovery

Neoadjuvant photodynamic therapy augments immediate and prolonged oxaliplatin efficacy in metastatic pancreatic cancer organoids

(2018) Mans Broekgaarden et al.   Oncotarget

A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening

(2018) Helen H.N. Yan et al.   Cell Stem Cell

Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

(2017) Laura Broutier et al.   NATURE MEDICINE

Organoids: Modeling Development and the Stem Cell Niche in a Dish

(2016) Kai Kretzschmar et al.   DEVELOPMENTAL CELL

EGFR targeted nanobody–photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer

(2016) Pieter B.A.A. van Driel et al.   JOURNAL OF CONTROLLED RELEASE

A meta-analysis comparing cisplatin-based to carboplatin-based chemotherapy in moderate to advanced squamous cell carcinoma of head and neck (SCCHN)

(2016) Jian Guan et al.   Oncotarget

Prognostic and predictive value of EGFR in head and neck squamous cell carcinoma

(2016) Paolo Bossi et al.   Oncotarget

Chemophototherapy: An Emerging Treatment Option for Solid Tumors

(2016) Dandan Luo et al.   Advanced Science

Boosting Tumor-Specific Immunity Using PDT

(2016) Nicole Maeding et al.   Cancers

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

Near Infrared Photoimmunotherapy in the Treatment of Disseminated Peritoneal Ovarian Cancer

(2014) K. Sato et al.   MOLECULAR CANCER THERAPEUTICS

Nanobody–photosensitizer conjugates for targeted photodynamic therapy

(2014) Raimond Heukers et al.   Nanomedicine-Nanotechnology Biology and Medicine

Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function, activatable immunoconjugates

(2014) B. Q. Spring et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocytosis of EGFR requires its kinase activity and N-terminal transmembrane dimerization motif

(2013) R. Heukers et al.   JOURNAL OF CELL SCIENCE

A Cell-Targeted Photodynamic Nanomedicine Strategy for Head and Neck Cancers

(2013) Alyssa Master et al.   MOLECULAR PHARMACEUTICS

A functional CFTR assay using primary cystic fibrosis intestinal organoids

(2013) Johanna F Dekkers et al.   NATURE MEDICINE

Photodynamic therapy of cancer: An update

(2011) Patrizia Agostinis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Photodynamic Therapy Using an Anti-EGF Receptor Antibody Complexed with Verteporfin Nanoparticles: A Proof of Concept Study

(2011) Noriaki Kameyama et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

(2011) Makoto Mitsunaga et al.   NATURE MEDICINE

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Head and neck cancer

(2008) Athanassios Argiris et al.   LANCET

Photophysics and photochemistry of photodynamic therapy: fundamental aspects

(2008) K. Plaetzer et al.   LASERS IN MEDICAL SCIENCE