SARS‐CoV‐2 infection remodels the host protein thermal stability landscape

Thermal proteome profiling for interrogating protein interactions

(2020) André Mateus et al.   Molecular Systems Biology

Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection

(2020) Yutaka Hashimoto et al.   Nature Communications

Proteomics of SARS-CoV-2-infected host cells reveals therapy targets

(2020) Denisa Bojkova et al.   NATURE

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

(2020) Mehdi Bouhaddou et al.   CELL

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

(2020) Chunlong Ma et al.   CELL RESEARCH

Data, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing

(2020) Jana Zecha et al.   MOLECULAR & CELLULAR PROTEOMICS

Critical Role of Type III Interferon in Controlling SARS-CoV-2 Infection in Human Intestinal Epithelial Cells

(2020) Megan L. Stanifer et al.   Cell Reports

The interface between coronaviruses and host cell RNA biology: Novel potential insights for future therapeutic intervention

(2020) David G. Maranon et al.   Wiley Interdisciplinary Reviews-RNA

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses

(2020) Abhik K. Banerjee et al.   CELL

Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection

(2020) Jin Wei et al.   CELL

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

(2020) David E. Gordon et al.   SCIENCE

The functional proteome landscape of Escherichia coli

(2020) André Mateus et al.   NATURE

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

(2019) Sindhuja Sridharan et al.   Nature Communications

Viral modulation of cellular RNA alternative splicing: A new key player in virus–host interactions?

(2019) Simon Boudreault et al.   Wiley Interdisciplinary Reviews-RNA

High throughput discovery of functional protein modifications by Hotspot Thermal Profiling

(2019) Jun X. Huang et al.   NATURE METHODS

Targeting Heat Shock Protein 27 in Cancer: A Druggable Target for Cancer Treatment?

(2019) Choi et al.   Cancers

Pervasive Protein Thermal Stability Variation during the Cell Cycle

(2018) Isabelle Becher et al.   CELL

Thermal proteome profiling in bacteria: probing protein state in vivo

(2018) André Mateus et al.   Molecular Systems Biology

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments

(2018) Christopher S. Hughes et al.   Nature Protocols

Heat Shock Protein 90 Ensures Efficient Mumps Virus Replication by Assisting with Viral Polymerase Complex Formation

(2017) Hiroshi Katoh et al.   JOURNAL OF VIROLOGY

Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat

(2016) Isabelle Becher et al.   Nature Chemical Biology

Thermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes

(2016) André Mateus et al.   Proteome Science

Connections matter - how viruses use cell-cell adhesion components

(2015) M. Mateo et al.   JOURNAL OF CELL SCIENCE

Mutations in Coronavirus Nonstructural Protein 10 Decrease Virus Replication Fidelity

(2015) Everett Clinton Smith et al.   JOURNAL OF VIROLOGY

Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry

(2015) Holger Franken et al.   Nature Protocols

Ultrasensitive proteome analysis using paramagnetic bead technology

(2014) C. S. Hughes et al.   Molecular Systems Biology

Tracking cancer drugs in living cells by thermal profiling of the proteome

(2014) M. M. Savitski et al.   SCIENCE

Inhibition of HSP90 attenuates porcine reproductive and respiratory syndrome virus production in vitro

(2014) Jintao Gao et al.   Virology Journal

Coronaviruses as DNA Wannabes: A New Model for the Regulation of RNA Virus Replication Fidelity

(2013) Everett Clinton Smith et al.   PLoS Pathogens

Spt6 levels are modulated by PAAF1 and proteasome to regulate the HIV-1 LTR

(2012) Mirai Nakamura et al.   Retrovirology

Broad action of Hsp90 as a host chaperone required for viral replication

(2011) Ron Geller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Inhibitory Mechanisms of the Tyrosine Kinase Inhibitors Herbimycin A, Genistein, and Tyrphostin B48 with Regard to the Function of the Aryl Hydrocarbon Receptor in Caco-2 Cells

(2010) Shuya KASAI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Association of the Influenza Virus RNA Polymerase Subunit PB2 with the Host Chaperonin CCT

(2010) T. Fislova et al.   JOURNAL OF VIROLOGY

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

(2009) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heat Shock Protein 90 Inhibitors Suppress Aryl Hydrocarbon Receptor-Mediated Activation of CYP1A1 and CYP1B1 Transcription and DNA Adduct Formation

(2008) D. Hughes et al.   Cancer Prevention Research