AT-RvD1 Mitigates Secondhand Smoke–Exacerbated Pulmonary Inflammation and Restores Secondhand Smoke–Suppressed Antibacterial Immunity

Quenching the fires: Pro-resolving mediators, air pollution, and smoking

(2019) Thomas H. Thatcher et al.   PHARMACOLOGY & THERAPEUTICS

Update on non-typeable Haemophilus influenzae-mediated disease and vaccine development

(2018) Farshid Jalalvand et al.   Expert Review of Vaccines

Key roles for lipid mediators in the adaptive immune response

(2018) Parker F. Duffney et al.   JOURNAL OF CLINICAL INVESTIGATION

Secondhand Smoke Induces Inflammation and Impairs Immunity to Respiratory Infections

(2018) Tariq A. Bhat et al.   JOURNAL OF IMMUNOLOGY

Tobacco Smoke Induces and Alters Immune Responses in the Lung Triggering Inflammation, Allergy, Asthma and Other Lung Diseases: A Mechanistic Review

(2018) Agnieszka Strzelak et al.   International Journal of Environmental Research and Public Health

Vaccines for the elderly: current use and future challenges

(2018) Birgit Weinberger   Immunity & Ageing

Alveolar Macrophages in the Resolution of Inflammation, Tissue Repair, and Tolerance to Infection

(2018) Benoit Allard et al.   Frontiers in Immunology

Ampicillin resistance in Haemophilus influenzae from COPD patients in the UK

(2017) Satyanarayana Maddi et al.   International Journal of Chronic Obstructive Pulmonary Disease

The association between environmental tobacco smoke exposure and childhood respiratory disease: a review

(2017) A. Vanker et al.   Expert Review of Respiratory Medicine

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

(2016) Peter J. Barnes   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Resolvin D1 Polarizes Primary Human Macrophages toward a Proresolution Phenotype through GPR32

(2016) Mattia Schmid et al.   JOURNAL OF IMMUNOLOGY

Neutrophil-generated oxidative stress and protein damage inStaphylococcus aureus

(2016) William N. Beavers et al.   Pathogens and Disease

Resolvin D1 Reduces Emphysema and Chronic Inflammation

(2015) Hsi-Min Hsiao et al.   AMERICAN JOURNAL OF PATHOLOGY

Resolvins Attenuate Inflammation and Promote Resolution in Cigarette Smoke-Exposed Human Macrophages

(2015) Amanda Croasdell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Soluble Epoxide Hydrolase Inhibitor Attenuates Inflammation and Airway Hyperresponsiveness in Mice

(2015) Jun Yang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3β-C/EBPβ pathway

(2015) Tomoki Maekawa et al.   Nature Communications

The Lung Immune Response to NontypeableHaemophilus influenzae(Lung Immunity to NTHi)

(2015) Paul T. King et al.   Journal of Immunology Research

Interrelated role of cigarette smoking, oxidative stress, and immune response in COPD and corresponding treatments

(2014) Li Zuo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cigarette Smoke-Induced Oxidative Stress Suppresses Generation of Dendritic Cell IL-12 and IL-23 through ERK-Dependent Pathways

(2014) P. R. Kroening et al.   JOURNAL OF IMMUNOLOGY

The Specialized Proresolving Mediator 17-HDHA Enhances the Antibody-Mediated Immune Response against Influenza Virus: A New Class of Adjuvant?

(2014) Sesquile Ramon et al.   JOURNAL OF IMMUNOLOGY

Cigarette Smoke Exposure Exacerbates Lung Inflammation and Compromises Immunity to Bacterial Infection

(2014) A. A. Lugade et al.   JOURNAL OF IMMUNOLOGY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Neu-164 and Neu-107, two novel antioxidant and anti-myeloperoxidase compounds, inhibit acute cigarette smoke-induced lung inflammation

(2013) Thomas H. Thatcher et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Tobacco Smoke–Induced Lung Fibrosis and Emphysema

(2013) Danielle Morse et al.   Annual Review of Physiology

Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway

(2013) Jae-Woong Hwang et al.   FASEB JOURNAL

50-Year Trends in Smoking-Related Mortality in the United States

(2013) Michael J. Thun et al.   NEW ENGLAND JOURNAL OF MEDICINE

Natural resolution of inflammation

(2013) Marcelo O. Freire et al.   PERIODONTOLOGY 2000

A Novel Anti-Inflammatory and Pro-Resolving Role for Resolvin D1 in Acute Cigarette Smoke-Induced Lung Inflammation

(2013) Hsi-Min Hsiao et al.   PLoS One

Cigarette smoke (CS) and nicotine delay neutrophil spontaneous death via suppressing production of diphosphoinositol pentakisphosphate

(2013) Y. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor

(2013) Patricia L. Podolin et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Resolvin D1 Receptor Stereoselectivity and Regulation of Inflammation and Proresolving MicroRNAs

(2012) Sriram Krishnamoorthy et al.   AMERICAN JOURNAL OF PATHOLOGY

Imbalance of Th17/Treg cells in mice with chronic cigarette smoke exposure

(2012) Huaying Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Increased expression of CD4+IL-17+ cells in the lung tissue of patients with stable chronic obstructive pulmonary disease (COPD) and smokers

(2012) Jianquan Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Specialized Proresolving Mediators Enhance Human B Cell Differentiation to Antibody-Secreting Cells

(2012) S. Ramon et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1 and Aspirin-Triggered Resolvin D1 Promote Resolution of Allergic Airways Responses

(2012) A. P. Rogerio et al.   JOURNAL OF IMMUNOLOGY

Aspirin-triggered resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury

(2012) O Eickmeier et al.   Mucosal Immunology

Targeting IL-17 and TH17 cells in chronic inflammation

(2012) Pierre Miossec et al.   NATURE REVIEWS DRUG DISCOVERY

Persistent Systemic Inflammation is Associated with Poor Clinical Outcomes in COPD: A Novel Phenotype

(2012) Alvar Agustí et al.   PLoS One

Resolvin D1 attenuates inflammation in lipopolysaccharide-induced acute lung injury through a process involving the PPARγ/NF-κB pathway

(2012) Zenglin Liao et al.   RESPIRATORY RESEARCH

Immunization in the adult immunocompromised host

(2011) Micha Löbermann et al.   AUTOIMMUNITY REVIEWS

Cigarette Smoking and Inflammation

(2011) J. Lee et al.   JOURNAL OF DENTAL RESEARCH

Omega-3 Fatty Acid-Derived Mediators 17(R)-Hydroxy Docosahexaenoic Acid, Aspirin-Triggered Resolvin D1 and Resolvin D2 Prevent Experimental Colitis in Mice

(2011) A. F. Bento et al.   JOURNAL OF IMMUNOLOGY

The Role of TLR2 and Bacterial Lipoprotein in Enhancing Airway Inflammation and Immunity

(2011) Amit A. Lugade et al.   Frontiers in Immunology

Novel Lipid Mediators and Resolution Mechanisms in Acute Inflammation

(2010) Charles N. Serhan   AMERICAN JOURNAL OF PATHOLOGY

Infection as a comorbidity of COPD

(2010) S. Sethi   EUROPEAN RESPIRATORY JOURNAL

MicroRNAs in resolution of acute inflammation: identification of novel resolvin D1-miRNA circuits

(2010) Antonio Recchiuti et al.   FASEB JOURNAL

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Sphingolipid-mediated Inhibition of Apoptotic Cell Clearance by Alveolar Macrophages

(2010) Daniela N. Petrusca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of an Autophagy Defect in Smokers' Alveolar Macrophages

(2010) M. M. Monick et al.   JOURNAL OF IMMUNOLOGY

Worldwide burden of disease from exposure to second-hand smoke: a retrospective analysis of data from 192 countries

(2010) Mattias Öberg et al.   LANCET

Bacteria Challenge in Smoke-exposed Mice Exacerbates Inflammation and Skews the Inflammatory Profile

(2009) Gordon J. Gaschler et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cigarette Smoke Exposure Impairs Pulmonary Bacterial Clearance and Alveolar Macrophage Complement-Mediated Phagocytosis of Streptococcus pneumoniae

(2009) J. C. Phipps et al.   INFECTION AND IMMUNITY

MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers

(2009) M. Seike et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction

(2008) K. F. Chung et al.   EUROPEAN RESPIRATORY JOURNAL

Environmental toxicity, redox signaling and lung inflammation: The role of glutathione

(2008) Saibal K. Biswas et al.   MOLECULAR ASPECTS OF MEDICINE

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Infection in the Pathogenesis and Course of Chronic Obstructive Pulmonary Disease

(2008) Sanjay Sethi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inflammatory Profile of New Bacterial Strain Exacerbations of Chronic Obstructive Pulmonary Disease

(2007) Sanjay Sethi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE