Soluble Epoxide Hydrolase Inhibitor Attenuates Inflammation and Airway Hyperresponsiveness in Mice

A Novel Prostacyclin Agonist Protects against Airway Hyperresponsiveness and Remodeling in Mice

(2012) Cristiane Yamabayashi et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Impact of Soluble Epoxide Hydrolase and Epoxyeicosanoids on Human Health

(2012) Christophe Morisseau et al.   Annual Review of Pharmacology and Toxicology

Resolvin D1 and Aspirin-Triggered Resolvin D1 Promote Resolution of Allergic Airways Responses

(2012) A. P. Rogerio et al.   JOURNAL OF IMMUNOLOGY

Metabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo

(2012) Suman Kundu et al.   JOURNAL OF LIPID RESEARCH

Asthma phenotypes: the evolution from clinical to molecular approaches

(2012) Sally E Wenzel   NATURE MEDICINE

Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes

(2012) B. Inceoglu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of a Soluble Epoxide Hydrolase Inhibitor in Smoke-Induced Chronic Obstructive Pulmonary Disease

(2011) Lei Wang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cytochrome P450-dependent eicosanoid production and crosstalk

(2011) Ingrid Fleming   CURRENT OPINION IN LIPIDOLOGY

Discovery of Inhibitors of Soluble Epoxide Hydrolase: A Target with Multiple Potential Therapeutic Indications

(2011) Hong C. Shen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP

(2011) B. Inceoglu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asthma and Allergic Inflammation

(2010) Richard M. Locksley   CELL

An update on the role of leukotrienes in asthma

(2010) Teal S Hallstrand et al.   Current Opinion in Allergy and Clinical Immunology

Cytochrome P450-Derived Epoxyeicosatrienoic Acids and Pulmonary Hypertension: Central Role of Transient Receptor Potential C6 Channels

(2010) Annemarieke E Loot et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

1-Aryl-3-(1-acylpiperidin-4-yl)urea Inhibitors of Human and Murine Soluble Epoxide Hydrolase: Structure−Activity Relationships, Pharmacokinetics, and Reduction of Inflammatory Pain

(2010) Tristan E. Rose et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nitric Oxide Synthase Enzymes in the Airways of Mice Exposed to Ovalbumin: NOS2 Expression Is NOS3 Dependent

(2010) Jennifer M. Bratt et al.   MEDIATORS OF INFLAMMATION

Quantitative Profiling Method for Oxylipin Metabolome by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry

(2009) Jun Yang et al.   ANALYTICAL CHEMISTRY

Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model

(2009) Jun-Yan Liu et al.   BIOCHEMICAL PHARMACOLOGY

Hypoxia-induced pulmonary hypertension: comparison of soluble epoxide hydrolase deletion vs. inhibition

(2009) Benjamin Keserü et al.   CARDIOVASCULAR RESEARCH

Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats

(2009) Marc Revermann et al.   JOURNAL OF HYPERTENSION

Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases

(2009) John D. Imig et al.   NATURE REVIEWS DRUG DISCOVERY

Mepolizumab for Prednisone-Dependent Asthma with Sputum Eosinophilia

(2009) Parameswaran Nair et al.   NEW ENGLAND JOURNAL OF MEDICINE

Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy

(2009) D. Ai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways

(2008) B. Inceoglu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin

(2008) Jennifer M. Bratt et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY