Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway

SIRT1 Mediates Central Circadian Control in the SCN by a Mechanism that Decays with Aging

(2013) Hung-Chun Chang et al.   CELL

Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1

(2013) Marina M. Bellet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of Anxiety and Depression on Chronic Obstructive Pulmonary Disease Exacerbation Risk

(2012) Catherine Laurin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comorbidities and Risk of Mortality in Patients with Chronic Obstructive Pulmonary Disease

(2012) Miguel Divo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Central and Peripheral Circadian Clocks in Mammals

(2012) Jennifer A. Mohawk et al.   Annual Review of Neuroscience

Role of Proinflammatory Cytokines on Lipopolysaccharide-Induced Phase Shifts in Locomotor Activity Circadian Rhythm

(2012) M. Juliana Leone et al.   CHRONOBIOLOGY INTERNATIONAL

The Circadian Clock Controls Toll-like Receptor 9-Mediated Innate and Adaptive Immunity

(2012) Adam C. Silver et al.   IMMUNITY

Circadian disruption alters mouse lung clock gene expression and lung mechanics

(2012) Hélène Hadden et al.   JOURNAL OF APPLIED PHYSIOLOGY

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

(2012) Hongwei Yao et al.   JOURNAL OF CLINICAL INVESTIGATION

Meal Time Shift Disturbs Circadian Rhythmicity along with Metabolic and Behavioral Alterations in Mice

(2012) Ji-Ae Yoon et al.   PLoS One

Core circadian protein CLOCK is a positive regulator of NF- B-mediated transcription

(2012) M. L. Spengler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines

(2012) R. Narasimamurthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathophysiology and pathogenesis of circadian rhythm sleep disorders

(2012) Akiko Hida et al.   Journal of Physiological Anthropology

Secondhand tobacco smoke, arterial stiffness, and altered circadian blood pressure patterns are associated with lung inflammation and oxidative stress in rats

(2011) Nicole J. Gentner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Circadian clock protein BMAL1 regulates cellular senescence in vivo

(2011) Rohini V. Khapre et al.   CELL CYCLE

Light-dark oscillations in the lung transcriptome: implications for lung homeostasis, repair, metabolism, disease, and drug action

(2011) Siddharth Sukumaran et al.   JOURNAL OF APPLIED PHYSIOLOGY

Smoking Cessation Interventions for Patients with Depression: A Systematic Review and Meta-analysis

(2011) Jennifer M. Gierisch et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

FOXO3 Deficiency Leads to Increased Susceptibility to Cigarette Smoke-Induced Inflammation, Airspace Enlargement, and Chronic Obstructive Pulmonary Disease

(2011) J.-w. Hwang et al.   JOURNAL OF IMMUNOLOGY

Circadian nature of immune function

(2011) Ryan W. Logan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The nuclear receptor REV-ERB  mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines

(2011) J. E. Gibbs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease

(2011) Hongwei Yao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Predictors of depression in chronic obstructive pulmonary disease patients

(2011) Sabina A Antoniu   Expert Review of Respiratory Medicine

Determinants of Depression in the ECLIPSE Chronic Obstructive Pulmonary Disease Cohort

(2010) Nicola A. Hanania et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks

(2010) Charna Dibner et al.   Annual Review of Physiology

SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress

(2010) Samuel Caito et al.   FASEB JOURNAL

Dysregulation of Inflammatory Responses by Chronic Circadian Disruption

(2010) O. Castanon-Cervantes et al.   JOURNAL OF IMMUNOLOGY

Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM

(2010) H. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian dysfunction in disease

(2010) David A. Bechtold et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Long-term stability and circadian variation in circulating levels of surfactant protein D

(2009) Silje Vermedal Hoegh et al.   IMMUNOBIOLOGY

Nr1d1, an Important Circadian Pathway Regulatory Gene, Is Suppressed By Cigarette Smoke in Murine Lungs

(2009) Vihas T. Vasu et al.   INTEGRATIVE CANCER THERAPIES

A circadian clock in macrophages controls inflammatory immune responses

(2009) Maren Keller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

(2009) Y. Nakahata et al.   SCIENCE

Genetic Ablation of NADPH Oxidase Enhances Susceptibility to Cigarette Smoke-Induced Lung Inflammation and Emphysema in Mice

(2008) Hongwei Yao et al.   AMERICAN JOURNAL OF PATHOLOGY

Short-term secondhand smoke exposure decreases heart rate variability and increases arrhythmia susceptibility in mice

(2008) Chao-Yin Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cigarette smoke-mediated inflammatory and oxidative responses are strain-dependent in mice

(2008) Hongwei Yao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

SIRT1, an Antiinflammatory and Antiaging Protein, Is Decreased in Lungs of Patients with Chronic Obstructive Pulmonary Disease

(2008) Saravanan Rajendrasozhan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SIRT1 Is a Circadian Deacetylase for Core Clock Components

(2008) William J. Belden et al.   CELL

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

Circadian Timing in the Lung; A Specific Role for Bronchiolar Epithelial Cells

(2008) J. E. Gibbs et al.   ENDOCRINOLOGY

Chromatin remodeling, metabolism and circadian clocks: The interplay of CLOCK and SIRT1

(2008) Benedetto Grimaldi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Injection of LPS Causes Transient Suppression of Biological Clock Genes in Rats

(2008) Kazuyuki Okada et al.   JOURNAL OF SURGICAL RESEARCH

Smoking in relation to anxiety and depression: Evidence from a large population survey: The HUNT study

(2007) Arnstein Mykletun et al.   EUROPEAN PSYCHIATRY