Adipose triglyceride lipase promotes the proliferation of colorectal cancer cells via enhancing the lipolytic pathway

Immune Profiling of Deficient Mismatch Repair Colorectal Cancer Tumor Microenvironment Reveals Different Levels of Immune System Activation

(2020) Riccardo Giannini et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Simulating the human colorectal cancer microenvironment in 3D tumor-stroma co-cultures in vitro and in vivo

(2020) Mahesh Devarasetty et al.   Scientific Reports

Changes in lipids composition and metabolism in colorectal cancer: a review

(2019) Alicja Pakiet et al.   Lipids in Health and Disease

ATGL promotes the proliferation of hepatocellular carcinoma cells via the p‐AKT signaling pathway

(2019) Meiling Liu et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Single-cell transcriptome analysis reveals tumor immune microenvironment heterogenicity and granulocytes enrichment in colorectal cancer liver metastases

(2019) Yunbin Zhang et al.   CANCER LETTERS

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Alkaline ceramidase 2 is essential for the homeostasis of plasma sphingoid bases and their phosphates

(2018) Fang Li et al.   FASEB JOURNAL

Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation

(2018) Xirui Liu et al.   Molecular Cancer

Hints on ATGL implications in cancer: beyond bioenergetic clues

(2018) Rolando Vegliante et al.   Cell Death & Disease

Forcing ATGL expression in hepatocarcinoma cells imposes glycolytic rewiring through PPAR-α/p300-mediated acetylation of p53

(2018) Luca Di Leo et al.   ONCOGENE

Mild mitochondrial uncoupling induces HSL/ATGL-independent lipolysis relying on a form of autophagy in 3T3-L1 adipocytes

(2017) Stéphane Demine et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism

(2017) Aishwarya Sathyanarayan et al.   Cell Reports

Epistatic interaction between the lipase-encoding genes Pnpla2 and Lipe causes liposarcoma in mice

(2017) Jiang Wei Wu et al.   PLoS Genetics

Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia

(2016) Wael Al-Zoughbi et al.   Oncotarget

Lipid metabolic reprogramming in cancer cells

(2016) S Beloribi-Djefaflia et al.   Oncogenesis

ATGL-Catalyzed Lipolysis Regulates SIRT1 to Control PGC-1α/PPAR-α Signaling

(2015) Salmaan Ahmed Khan et al.   DIABETES

The Warburg effect: Evolving interpretations of an established concept

(2015) Xiaozhuo Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells

(2015) Rachid Zagani et al.   Oncotarget

The Role of Monoacylglycerol Lipase (MAGL) in the Cancer Progress

(2014) Hong Qin et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism

(2014) Kuok Teong Ong et al.   JOURNAL OF LIPID RESEARCH

Proline oxidase–adipose triglyceride lipase pathway restrains adipose cell death and tissue inflammation

(2013) D Lettieri Barbato et al.   CELL DEATH AND DIFFERENTIATION

Biochemistry and pathophysiology of intravascular and intracellular lipolysis

(2013) S. G. Young et al.   GENES & DEVELOPMENT

Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia

(2013) Pooja Jha et al.   HEPATOLOGY

Panitumumab–FOLFOX4 Treatment and RAS Mutations in Colorectal Cancer

(2013) Jean-Yves Douillard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation

(2012) Kuok Teong Ong et al.   FASEB JOURNAL

Monoacylglycerol lipase (MAGL) knockdown inhibits tumor cells growth in colorectal cancer

(2011) Lin Ye et al.   CANCER LETTERS

Dual inhibition of MAGL and type II topoisomerase by N-phenylmaleimides as a potential strategy to reduce neuroblastoma cell growth

(2011) Nicolas Matuszak et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

(2011) Guenter Haemmerle et al.   NATURE MEDICINE

Hepatic Overexpression of Hormone-sensitive Lipase and Adipose Triglyceride Lipase Promotes Fatty Acid Oxidation, Stimulates Direct Release of Free Fatty Acids, and Ameliorates Steatosis

(2008) Brendan N. Reid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY