Alkaline ceramidase 2 is essential for the homeostasis of plasma sphingoid bases and their phosphates

Sphingosine 1-Phosphate Receptor 1 Signaling in Mammalian Cells

(2017) Nigel Pyne et al.   MOLECULES

Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor

(2017) Takashi Onuma et al.   THROMBOSIS RESEARCH

Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells

(2017) Chih-Li Lin et al.   Stem Cell Reports

Platelet and Erythrocyte Sources of S1P Are Redundant for Vascular Development and Homeostasis, but Both Rendered Essential After Plasma S1P Depletion in Anaphylactic ShockNovelty and Significance

(2016) Salomé L. Gazit et al.   CIRCULATION RESEARCH

Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy

(2015) Richard L. Proia et al.   JOURNAL OF CLINICAL INVESTIGATION

Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain

(2015) Kai Wang et al.   PLoS Genetics

Erythrocyte-derived sphingosine 1-phosphate is essential for vascular development

(2014) Yuquan Xiong et al.   JOURNAL OF CLINICAL INVESTIGATION

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

(2014) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

PhotoImmunoNanoTherapy Reveals an Anticancer Role for Sphingosine Kinase 2 and Dihydrosphingosine-1-Phosphate

(2013) Brian M. Barth et al.   ACS Nano

Sphingosine 1-phosphate signalling

(2013) K. Mendelson et al.   DEVELOPMENT

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Sphingosine-1-Phosphate and Lymphocyte Egress from Lymphoid Organs

(2012) Jason G. Cyster et al.   Annual Review of Immunology

Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 β-cell survival

(2012) Julien Véret et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease

(2012) Ashley J. Snider et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Distinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydrosphingosine 1-phosphate in human neural progenitor cells

(2011) Phillip Callihan et al.   NEUROPHARMACOLOGY

Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes

(2010) Ruijuan Xu et al.   FASEB JOURNAL

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

(2010) Sergio E. Alvarez et al.   NATURE

International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature

(2010) J. Chun et al.   PHARMACOLOGICAL REVIEWS

UPLC–MS/MS method for analysis of sphingosine 1-phosphate in biological samples

(2010) Adele Cutignano et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Incomplete Inhibition of Sphingosine 1-Phosphate Lyase Modulates Immune System Function yet Prevents Early Lethality and Non-Lymphoid Lesions

(2009) Peter Vogel et al.   PLoS One

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

(2009) N. C. Hait et al.   SCIENCE

Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate

(2008) C MAO   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

(2008) Krishnan Venkataraman et al.   CIRCULATION RESEARCH

Opposite Effects of Dihydrosphingosine 1-Phosphate and Sphingosine 1-Phosphate on Transforming Growth Factor-β/Smad Signaling Are Mediated through the PTEN/PPM1A-dependent Pathway

(2008) Shizhong Bu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY