Distinct protein architectures mediate species-specific beta-glucan binding and metabolism in the human gut microbiota

Synergy between Cell Surface Glycosidases and Glycan-Binding Proteins Dictates the Utilization of Specific Beta(1,3)-Glucans by Human Gut Bacteroides

(2020) Guillaume Déjean et al.   mBio

Glycan utilization systems in the human gut microbiota: a gold mine for structural discoveries

(2020) Kazune Tamura et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Transforming medicine with the microbiome

(2019) Niv Zmora et al.   Science Translational Medicine

Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus

(2019) Kazune Tamura et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci

(2019) Justina Briliūtė et al.   Nature Microbiology

Diet–microbiota interactions and personalized nutrition

(2019) Aleksandra A. Kolodziejczyk et al.   NATURE REVIEWS MICROBIOLOGY

DALI and the persistence of protein shape

(2019) Liisa Holm   PROTEIN SCIENCE

The Starch Utilization System Assembles around Stationary Starch-Binding Proteins

(2018) Hannah H. Tuson et al.   BIOPHYSICAL JOURNAL

SusE facilitates starch uptake independent of starch binding in B. thetaiotaomicron

(2018) Matthew H. Foley et al.   MOLECULAR MICROBIOLOGY

Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

(2018) Liping Zhao et al.   SCIENCE

Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont

(2018) Benjamin Pluvinage et al.   Nature Communications

CCP4i2: the new graphical user interface to the CCP4 program suite

(2018) Liz Potterton et al.   Acta Crystallographica Section D-Structural Biology

DIALS: implementation and evaluation of a new integration package

(2018) Graeme Winter et al.   Acta Crystallographica Section D-Structural Biology

You are what you eat: diet, health and the gut microbiota

(2018) Niv Zmora et al.   Nature Reviews Gastroenterology & Hepatology

Molecular recognition of the beta-glucans laminarin and pustulan by a SusD-like glycan-binding protein of a marine Bacteroidetes

(2018) Agata Anna Mystkowska et al.   FEBS Journal

A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation

(2018) Alan Cartmell et al.   Nature Microbiology

Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes

(2017)   GLYCOBIOLOGY

Polysaccharide Utilization Loci: Fueling Microbial Communities

(2017) Julie M. Grondin et al.   JOURNAL OF BACTERIOLOGY

A Bacteroidetes locus dedicated to fungal 1,6-β-glucan degradation: Unique substrate conformation drives specificity of the key endo-1,6-β-glucanase

(2017) Max J. Temple et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for nutrient acquisition by dominant members of the human gut microbiota

(2017) Amy J. Glenwright et al.   NATURE

Complex pectin metabolism by gut bacteria reveals novel catalytic functions

(2017) Didier Ndeh et al.   NATURE

PULDB: the expanded database of Polysaccharide Utilization Loci

(2017) Nicolas Terrapon et al.   NUCLEIC ACIDS RESEARCH

How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans

(2017) Alan Cartmell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: More and better reference data for improved all-atom structure validation

(2017) Christopher J. Williams et al.   PROTEIN SCIENCE

Carrageenan catabolism is encoded by a complex regulon in marine heterotrophic bacteria

(2017) Elizabeth Ficko-Blean et al.   Nature Communications

Molecular Mechanism by which Prominent Human Gut Bacteroidetes Utilize Mixed-Linkage Beta-Glucans, Major Health-Promoting Cereal Polysaccharides

(2017) Kazune Tamura et al.   Cell Reports

Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides

(2017) Ana S. Luis et al.   Nature Microbiology

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

Reduction in circulating bile acid and restricted diffusion across the intestinal epithelium are associated with a decrease in blood cholesterol in the presence of oat β-glucan

(2016) Purnima Gunness et al.   FASEB JOURNAL

Molecular Dissection of Xyloglucan Recognition in a Prominent Human Gut Symbiont

(2016) Alexandra S. Tauzin et al.   mBio

Structural dissection of a complexBacteroides ovatusgene locus conferring xyloglucan metabolism in the human gut

(2016) Glyn R. Hemsworth et al.   Open Biology

Microbiota in Allergy and Asthma and the Emerging Relationship with the Gut Microbiome

(2015) Kei E. Fujimura et al.   Cell Host & Microbe

Molecular Interactions of β-(1→3)-Glucans with Their Receptors

(2015) Laurent Legentil et al.   MOLECULES

Privateer: software for the conformational validation of carbohydrate structures

(2015) Jon Agirre et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Glycan complexity dictates microbial resource allocation in the large intestine

(2015) Artur Rogowski et al.   Nature Communications

Privateer: software for the conformational validation of carbohydrate structures

(2015) Jon Agirre et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes

(2014) Johan Larsbrink et al.   NATURE

Multifunctional Nutrient-Binding Proteins Adapt Human Symbiotic Bacteria for Glycan Competition in the Gut by Separately Promoting Enhanced Sensing and Catalysis

(2014) E. A. Cameron et al.   mBio

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Super-Resolution Imaging of Live Anaerobic Bacteria: Assembly and Dynamics of the B. Theta Starch Utilization System

(2013) Krishanthi Karunatilaka et al.   BIOPHYSICAL JOURNAL

Advances in understanding the molecular basis of plant cell wall polysaccharide recognition by carbohydrate-binding modules

(2013) Harry J Gilbert et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

The abundance and variety of carbohydrate-active enzymes in the human gut microbiota

(2013) Abdessamad El Kaoutari et al.   NATURE REVIEWS MICROBIOLOGY

The carbohydrate-active enzymes database (CAZy) in 2013

(2013) Vincent Lombard et al.   NUCLEIC ACIDS RESEARCH

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Glycan recognition by the Bacteroidetes Sus-like systems

(2012) David N Bolam et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Multidomain Carbohydrate-binding Proteins Involved inBacteroides thetaiotaomicronStarch Metabolism

(2012) Elizabeth A. Cameron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How glycan metabolism shapes the human gut microbiota

(2012) Nicole M. Koropatkin et al.   NATURE REVIEWS MICROBIOLOGY

Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes

(2012) J.-H. Hehemann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Data processing and analysis with theautoPROCtoolbox

(2011) Clemens Vonrhein et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Recognition and Degradation of Plant Cell Wall Polysaccharides by Two Human Gut Symbionts

(2011) Eric C. Martens et al.   PLOS BIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Transfer of carbohydrate-active enzymes from marine bacteria to Japanese gut microbiota

(2010) Jan-Hendrik Hehemann et al.   NATURE

Decision-making in structure solution using Bayesian estimates of map quality: thePHENIX AutoSolwizard

(2009) Thomas C. Terwilliger et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of a SusD Homologue, BT1043, Involved in MucinO-Glycan Utilization in a Prominent Human Gut Symbiont†,‡

(2009) Nicole Koropatkin et al.   BIOCHEMISTRY

xia2: an expert system for macromolecular crystallography data reduction

(2009) G. Winter   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols

Starch Catabolism by a Prominent Human Gut Symbiont Is Directed by the Recognition of Amylose Helices

(2008) Nicole M. Koropatkin et al.   STRUCTURE