Galectin-9 bridges human B cells to vascular endothelium while programming regulatory pathways

Cosmc controls B cell homing

(2020) Junwei Zeng et al.   Nature Communications

Galectin-9 promotes a suppressive microenvironment in human cancer by enhancing STING degradation

(2020) Chuan-xia Zhang et al.   Oncogenesis

Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7

(2019) Jiro Kikuchi et al.   LEUKEMIA

L-selectin: A Major Regulator of Leukocyte Adhesion, Migration and Signaling

(2019) Aleksandar Ivetic et al.   Frontiers in Immunology

The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer

(2019) Inna M. Yasinska et al.   Frontiers in Immunology

VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis

(2018) MacIntosh Cornwell et al.   BMC BIOINFORMATICS

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models

(2018) Santosh K. Panda et al.   JOURNAL OF CLINICAL INVESTIGATION

Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans

(2018) N. Giovannone et al.   Nature Communications

Galectin-9 binds IgM-BCR to regulate B cell signaling

(2018) Anh Cao et al.   Nature Communications

Human B Cell Differentiation Is Characterized by Progressive Remodeling of O-Linked Glycans

(2018) Nicholas Giovannone et al.   Frontiers in Immunology

Galectin-Glycan Interactions as Regulators of B Cell Immunity

(2018) Nicholas Giovannone et al.   Frontiers in Immunology

Galectin-9 binds to O-glycans on protein disulfide isomerase

(2017) Katrin Schaefer et al.   GLYCOBIOLOGY

Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology

(2017) Mariana Silva et al.   JOURNAL OF IMMUNOLOGY

Galectins and Immune Responses—Just How Do They Do Those Things They Do?

(2016) Sandra Thiemann et al.   Annual Review of Immunology

CRACC-targeting Fc-fusion protein induces activation of NK cells and DCs and improves T cell immune responses to antigenic targets

(2016) Yasser A. Aldhamen et al.   VACCINE

Galectin-Binding O-Glycosylations as Regulators of Malignancy

(2015) C. J. Dimitroff   CANCER RESEARCH

Human Cytomegalovirus Upregulates Expression of the Lectin Galectin 9 via Induction of Beta Interferon

(2014) B. P. McSharry et al.   JOURNAL OF VIROLOGY

Immune Cell Inhibition by SLAMF7 Is Mediated by a Mechanism Requiring Src Kinases, CD45, and SHIP-1 That Is Defective in Multiple Myeloma Cells

(2014) Huaijian Guo et al.   MOLECULAR AND CELLULAR BIOLOGY

Improved cytotoxic T-lymphocyte immune responses to a tumor antigen by vaccines co-expressing the SLAM-associated adaptor EAT-2

(2013) Y A Aldhamen et al.   CANCER GENE THERAPY

Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategy

(2013) Yasser A. Aldhamen et al.   INTERNATIONAL IMMUNOLOGY

Galectin-9 Ameliorates Clinical Severity of MRL/lpr Lupus-Prone Mice by Inducing Plasma Cell Apoptosis Independently of Tim-3

(2013) Masahiro Moritoki et al.   PLoS One

Galectin-9 Is a Suppressor of T and B Cells and Predicts the Immune Modulatory Potential of Mesenchymal Stromal Cell Preparations

(2013) Christopher Ungerer et al.   STEM CELLS AND DEVELOPMENT

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

FAK and PAX-illin get involved in leukocyte diapedesis

(2012) Francis W. Luscinskas   EUROPEAN JOURNAL OF IMMUNOLOGY

A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins

(2012) S. L. Orr et al.   GLYCOBIOLOGY

Galectins and their ligands: negative regulators of anti-tumor immunity

(2012) Filiberto Cedeno-Laurent et al.   GLYCOCONJUGATE JOURNAL

Vaccines Expressing the Innate Immune Modulator EAT-2 Elicit Potent Effector Memory T Lymphocyte Responses despite Pre-Existing Vaccine Immunity

(2012) Y. A. Aldhamen et al.   JOURNAL OF IMMUNOLOGY

Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks

(2012) Deepali Malhotra et al.   NATURE IMMUNOLOGY

Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors

(2011) Lela Kardava et al.   JOURNAL OF CLINICAL INVESTIGATION

Therapeutic potential of Galectin-9 in human disease

(2011) Valerie R. Wiersma et al.   MEDICINAL RESEARCH REVIEWS

T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses

(2011) S. Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry

(2011) S. Bi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of SLAM (CD150) cell-surface receptors on human B-cell subsets: From pro-B to plasma cells

(2010) Jose De Salort et al.   IMMUNOLOGY LETTERS

Expression of the SLAM Family of Receptors Adapter EAT-2 as a Novel Strategy for Enhancing Beneficial Immune Responses to Vaccine Antigens

(2010) Y. A. Aldhamen et al.   JOURNAL OF IMMUNOLOGY

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

MEK/ERK-Mediated Phosphorylation of Bim Is Required to Ensure Survival of T and B Lymphocytes during Mitogenic Stimulation

(2009) L. A. O'Reilly et al.   JOURNAL OF IMMUNOLOGY

Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function

(2009) Mario-Ernesto Cruz-Munoz et al.   NATURE IMMUNOLOGY

CS1, a Potential New Therapeutic Antibody Target for the Treatment of Multiple Myeloma

(2008) E. D. Hsi et al.   CLINICAL CANCER RESEARCH

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis

(2008) Masako Seki et al.   CLINICAL IMMUNOLOGY