Convergence: Lactosylceramide-Centric Signaling Pathways Induce Inflammation, Oxidative Stress, and Other Phenotypic Outcomes

Management of metabolic syndrome and reduction in body weight in type II diabetic mice by inhibiting glycosphingolipid synthesis

(2020) Subroto Chatterjee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sphingosine-1-phosphate: From insipid lipid to a key regulator

(2020) Sarah Spiegel   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional activities of beta-glucans in the prevention or treatment of cervical cancer

(2020) Shahla Chaichian et al.   Journal of Ovarian Research

UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells

(2020) Nina Schömel et al.   Scientific Reports

Lactosylceramide induced by elastin-derived peptides decreases adipocyte differentiation

(2020) Thinhinane Hocine et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Influence of glycosphingolipids on cancer cell energy metabolism

(2020) Nina Schömel et al.   PROGRESS IN LIPID RESEARCH

Sphingolipid Analysis Indicate Lactosylceramide as a Potential Biomarker of Inflammatory Bowel Disease in Children

(2020) Aleksandra Filimoniuk et al.   Biomolecules

Specific alterations of sphingolipid metabolism identified in EpCAM-positive cells isolated from human colon tumors

(2020) Jiřina Procházková et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Exploratory analysis of large-scale lipidome in large cohorts: are we any closer of finding lipid-based markers suitable for CVD risk stratification and management?

(2020) Sílvia O. Diaz et al.   ANALYTICA CHIMICA ACTA

Untargeted Metabolomics and Inflammatory Markers Profiling in Children With Crohn’s Disease and Ulcerative Colitis—A Preliminary Study

(2019) Urszula Daniluk et al.   INFLAMMATORY BOWEL DISEASES

TNF Induces Pathogenic Programmed Macrophage Necrosis in Tuberculosis through a Mitochondrial-Lysosomal-Endoplasmic Reticulum Circuit

(2019) Francisco J. Roca et al.   CELL

Colon Cancer and Perturbations of the Sphingolipid Metabolism

(2019) Miroslav Machala et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NADPH oxidase activation in neutrophils: Role of the phosphorylation of its subunits

(2018) Sahra A. Belambri et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Role of sphingolipids in senescence: implication in aging and age-related diseases

(2018) Magali Trayssac et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of glycosphingolipid synthesis reverses skin inflammation and hair loss in ApoE−/− mice fed western diet

(2018) Djahida Bedja et al.   Scientific Reports

Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice

(2018) Toru Yoshihara et al.   PLoS Genetics

Lactosylceramide synthase β-1,4-GalT-V: A novel target for the diagnosis and therapy of human colorectal cancer

(2018) Subroto B. Chatterjee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The regulatory roles of glycosphingolipid‐enriched lipid rafts in immune systems

(2018) Hitoshi Nakayama et al.   FEBS LETTERS

PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum

(2017) Takashi Ode et al.   EXPERIMENTAL CELL RESEARCH

Identification of hair shaft progenitors that create a niche for hair pigmentation

(2017) Chung-Ping Liao et al.   GENES & DEVELOPMENT

Differential reactive oxygen species production of neutrophils and their oxidative damage in patients with active and inactive systemic lupus erythematosus

(2017) Nesrine Elloumi et al.   IMMUNOLOGY LETTERS

Lactosylceramide-Induced Phosphorylation Signaling to Group IVA Phospholipase A2 via Reactive Oxygen Species in Tumor Necrosis Factor-α-Treated Cells

(2017) Hiroyuki Nakamura et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Sphingolipids and their metabolism in physiology and disease

(2017) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Plasma Lipidomic Profiles Improve on Traditional Risk Factors for the Prediction of Cardiovascular Events in Type 2 Diabetes MellitusClinical Perspective

(2016) Zahir H. Alshehry et al.   CIRCULATION

Lactosylceramide contributes to mitochondrial dysfunction in diabetes

(2016) Sergei A. Novgorodov et al.   JOURNAL OF LIPID RESEARCH

Lactosylceramide-accumulation in lipid-rafts mediate aberrant-autophagy, inflammation and apoptosis in cigarette smoke induced emphysema

(2015) Manish Bodas et al.   APOPTOSIS

Prevention of cardiac hypertrophy by the use of a glycosphingolipid synthesis inhibitor in ApoE−/− mice

(2015) Sumita Mishra et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Involvement of glycosphingolipid-enriched lipid rafts in inflammatory responses

(2015) Kazuhisa Iwabuchi   Frontiers in Bioscience-Landmark

Properties and functions of lactosylceramide from mouse neutrophils

(2015) K. Iwabuchi et al.   GLYCOBIOLOGY

Association between Arterial Stiffness and Serum L-Octanoylcarnitine and Lactosylceramide in Overweight Middle-Aged Subjects: 3-Year Follow-Up Study

(2015) Minjoo Kim et al.   PLoS One

Inhibition of Glycosphingolipid Synthesis Ameliorates Atherosclerosis and Arterial Stiffness in Apolipoprotein E −/− Mice and Rabbits Fed a High-Fat and -Cholesterol Diet

(2014) Subroto Chatterjee et al.   CIRCULATION

Lactosylceramide Interacts with and Activates Cytosolic Phospholipase A2α

(2013) Hiroyuki Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Use of a Glycolipid Inhibitor to Ameliorate Renal Cancer in a Mouse Model

(2013) Subroto Chatterjee et al.   PLoS One

Higher circulating levels of OxLDL % of LDL are associated with subclinical atherosclerosis in female patients with systemic lupus erythematosus

(2013) Hamada Mohammad Ahmad et al.   RHEUMATOLOGY INTERNATIONAL

β1,4-Galactosyltransferase V regulates self-renewal of glioma-initiating cell

(2010) Yuanyan Wei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

(2010) Mi-Jeong Kim et al.   EMBO Molecular Medicine

β4-Galactosyltransferase-5 is a lactosylceramide synthase essential for mouse extra-embryonic development

(2010) Toshikazu Nishie et al.   GLYCOBIOLOGY

Involvement of murine β-1,4-galactosyltransferase V in lactosylceramide biosynthesis

(2010) Tadahiro Kumagai et al.   GLYCOCONJUGATE JOURNAL

Regulation of the  1,4-Galactosyltransferase I promoter by E2F1

(2010) Y. Wei et al.   JOURNAL OF BIOCHEMISTRY

Critical Modifier Role of Membrane-Cystic Fibrosis Transmembrane Conductance Regulator-Dependent Ceramide Signaling in Lung Injury and Emphysema

(2010) M. Bodas et al.   JOURNAL OF IMMUNOLOGY

Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models

(2010) Thomas A Natoli et al.   NATURE MEDICINE

VEGF recruits lactosylceramide to induce endothelial cell adhesion molecule expression and angiogenesis in vitro and in vivo

(2009) Antonina Kolmakova et al.   GLYCOCONJUGATE JOURNAL

Ceramide and Mitochondria in Ischemia/Reperfusion

(2009) Sergei A Novgorodov et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Sphingolipids in the Lungs

(2008) Stefan Uhlig et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regulation of Lactosylceramide Synthase (Glucosylceramide β1→4 Galactosyltransferase); Implication as A Drug Target

(2008) Subroto Chatterjee et al.   CURRENT DRUG TARGETS

Roles of plasma membrane-associated sialidase NEU3 in human cancers

(2007) Taeko Miyagi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Yin and Yang of lactosylceramide metabolism: Implications in cell function

(2007) Subroto Chatterjee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS