Nuclear Reorganization in Hippocampal Granule Cell Neurons from a Mouse Model of Down Syndrome: Changes in Chromatin Configuration, Nucleoli and Cajal Bodies

Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories

(2020) Thomas Hainmueller et al.   NATURE REVIEWS NEUROSCIENCE

Down syndrome

(2020) Stylianos E. Antonarakis et al.   Nature Reviews Disease Primers

Prenatal, but not Postnatal, Curcumin Administration Rescues Neuromorphological and Cognitive Alterations in Ts65Dn Down Syndrome Mice

(2020) Noemí Rueda et al.   JOURNAL OF NUTRITION

Cytogenetic instability of chromosomal nucleolar organizer regions (NORs) in cloned mouse L929 fibroblasts

(2019) Olga V. Zatsepina   CHROMOSOME RESEARCH

Maternal choline supplementation alters basal forebrain cholinergic neuron gene expression in the Ts65Dn mouse model of Down syndrome

(2019) Christy M. Kelley et al.   Developmental Neurobiology

Reorganization of the nuclear compartments involved in transcription and RNA processing in myonuclei of type I spinal muscular atrophy

(2019) María S. Castillo-Iglesias et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Nucleolin reorganization and nucleolar stress in Purkinje cells of mutant PCD mice

(2019) Fernando C. Baltanás et al.   NEUROBIOLOGY OF DISEASE

Nucleolar dynamics and interactions with nucleoplasm in living cells

(2019) Christina M Caragine et al.   eLife

Dynamics and Function of Nuclear Bodies during Embryogenesis

(2018) Dahyana Arias Escayola et al.   BIOCHEMISTRY

Treatment with corn oil improves neurogenesis and cognitive performance in the Ts65Dn mouse model of Down syndrome

(2018) Andrea Giacomini et al.   BRAIN RESEARCH BULLETIN

Molecular mechanisms driving transcriptional stress responses

(2018) Anniina Vihervaara et al.   NATURE REVIEWS GENETICS

Accumulation of poly(A) RNA in nuclear granules enriched in Sam68 in motor neurons from the SMNΔ7 mouse model of SMA

(2018) J. Oriol Narcís et al.   Scientific Reports

Interchromosomal interactions: A genomic love story of kissing chromosomes

(2018) Philipp G. Maass et al.   JOURNAL OF CELL BIOLOGY

Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing

(2018) Muhammad Shoaib et al.   Nature Communications

Nuclear Architecture in the Nervous System: Development, Function, and Neurodevelopmental Diseases

(2018) Kenji Ito et al.   Frontiers in Genetics

Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome

(2017) Alexander M. Kleschevnikov et al.   NEUROBIOLOGY OF DISEASE

Cellular bases of the RNA metabolism dysfunction in motor neurons of a murine model of spinal muscular atrophy: Role of Cajal bodies and the nucleolus

(2017) Olga Tapia et al.   NEUROBIOLOGY OF DISEASE

Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes

(2017) Susana García-Cerro et al.   NEUROBIOLOGY OF DISEASE

Trans-acting epigenetic effects of chromosomal aneuploidies: lessons from Down syndrome and mouse models

(2017) Catherine Do et al.   Epigenomics

Molecular dynamics of histone H1

(2016) Thomas W. Flanagan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Nucleation by rRNA Dictates the Precision of Nucleolus Assembly

(2016) Hanieh Falahati et al.   CURRENT BIOLOGY

Nucleolar organizer regions: genomic ‘dark matter’ requiring illumination

(2016) Brian McStay   GENES & DEVELOPMENT

Mouse models of Down syndrome: gene content and consequences

(2016) Meenal Gupta et al.   MAMMALIAN GENOME

Epigenomic engineering for Down syndrome

(2016) A.F. Mentis   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Towards an understanding of regulating Cajal body activity by protein modification

(2016) Michael D. Hebert et al.   RNA Biology

Cajal bodies are linked to genome conformation

(2016) Qiuyan Wang et al.   Nature Communications

Altered Machinery of Protein Synthesis in Alzheimer's: From the Nucleolus to the Ribosome

(2015) Karina Hernández-Ortega et al.   BRAIN PATHOLOGY

Assembly of the nucleolus: in need of revision

(2015) M. Carmo-Fonseca   EMBO JOURNAL

Alu element-containing RNAs maintain nucleolar structure and function

(2015) M. Caudron-Herger et al.   EMBO JOURNAL

The interplay of histone modifications - writers that read

(2015) T. Zhang et al.   EMBO REPORTS

Dynamic Behavior of the RNA Polymerase II and the Ubiquitin Proteasome System During the Neuronal DNA Damage Response to Ionizing Radiation

(2015) Iñigo Casafont et al.   MOLECULAR NEUROBIOLOGY

Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice

(2014) Melissa J. Alldred et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The Coilin Interactome Identifies Hundreds of Small Noncoding RNAs that Traffic through Cajal Bodies

(2014) Martin Machyna et al.   MOLECULAR CELL

Domains of genome-wide gene expression dysregulation in Down’s syndrome

(2014) Audrey Letourneau et al.   NATURE

A day in the life of the spliceosome

(2014) A. Gregory Matera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reactive nucleolar and Cajal body responses to proteasome inhibition in sensory ganglion neurons

(2013) Ana Palanca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Characterization of nucleolin K88 acetylation defines a new pool of nucleolin colocalizing with pre-mRNA splicing factors

(2013) Sadhan Das et al.   FEBS LETTERS

Micron-scale coherence in interphase chromatin dynamics

(2013) A. Zidovska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biotinylation of lysine 16 in histone H4 contributes toward nucleosome condensation

(2012) Mahendra P. Singh et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Nucleolar activity in neurodegenerative diseases: a missing piece of the puzzle?

(2012) Rosanna Parlato et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Transcriptional consequences of aneuploidy

(2012) J. M. Sheltzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disease Modeling Using Embryonic Stem Cells: MeCP2 Regulates Nuclear Size and RNA Synthesis in Neurons

(2012) Morteza Yazdani et al.   STEM CELLS

Emerging roles of the neuronal nucleolus

(2012) Michal Hetman et al.   TRENDS IN NEUROSCIENCES

Cajal bodies: where form meets function

(2012) Martin Machyna et al.   Wiley Interdisciplinary Reviews-RNA

Mouse Models of Down Syndrome as a Tool to Unravel the Causes of Mental Disabilities

(2012) Noemí Rueda et al.   NEURAL PLASTICITY

Transcription factories

(2012) Dietmar Rieder et al.   Frontiers in Genetics

Transcript catalogs of human chromosome 21 and orthologous chimpanzee and mouse regions

(2011) Xiaolu Sturgeon et al.   MAMMALIAN GENOME

Coilin participates in the suppression of RNA polymerase I in response to cisplatin-induced DNA damage

(2011) Andrew S. Gilder et al.   MOLECULAR BIOLOGY OF THE CELL

Nucleation of nuclear bodies by RNA

(2011) Sergey P. Shevtsov et al.   NATURE CELL BIOLOGY

MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation

(2011) Malaika K. Singleton et al.   NEUROBIOLOGY OF DISEASE

Is it possible to improve neurodevelopmental abnormalities in Down syndrome?

(2011) Renata Bartesaghi et al.   REVIEWS IN THE NEUROSCIENCES

Biogenesis and function of nuclear bodies

(2011) Yuntao S. Mao et al.   TRENDS IN GENETICS

Trisomy 21 and early brain development

(2011) Tarik F. Haydar et al.   TRENDS IN NEUROSCIENCES

Nucleolar Disruption and Cajal Body Disassembly are Nuclear Hallmarks of DNA Damage-Induced Neurodegeneration in Purkinje Cells

(2010) Fernando C. Baltanás et al.   BRAIN PATHOLOGY

Binding of the Rett syndrome protein, MeCP2, to methylated and unmethylated DNA and chromatin

(2010) Jeffrey C. Hansen et al.   IUBMB LIFE

The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes

(2010) Rachit Bakshi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Novel histone biotinylation marks are enriched in repeat regions and participate in repression of transcriptionally competent genes

(2010) Valerie Pestinger et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of voluntary physical exercise on adult hippocampal neurogenesis and behavior of Ts65Dn mice, a model of Down syndrome

(2010) M.V. Llorens-Martín et al.   NEUROSCIENCE

Chromosome Territories

(2010) T. Cremer et al.   Cold Spring Harbor Perspectives in Biology

The nucleolus: structure/function relationship in RNA metabolism

(2010) Danièle Hernandez-Verdun et al.   Wiley Interdisciplinary Reviews-RNA

Cajal’s contribution to the knowledge of the neuronal cell nucleus

(2009) Miguel Lafarga et al.   CHROMOSOMA

Sizing up the nucleus: nuclear shape, size and nuclear-envelope assembly

(2009) M. Webster et al.   JOURNAL OF CELL SCIENCE

Prevalence of Down Syndrome Among Children and Adolescents in 10 Regions of the United States

(2009) M. Shin et al.   PEDIATRICS

DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome

(2008) Claudia Canzonetta et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mental retardation and associated neurological dysfunctions in Down syndrome: A consequence of dysregulation in critical chromosome 21 genes and associated molecular pathways

(2008) Mohammed Rachidi et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

SUMO-1 transiently localizes to Cajal bodies in mammalian neurons

(2008) J. Navascues et al.   JOURNAL OF STRUCTURAL BIOLOGY