COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

(2020) Dawei Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Immunoinformatics‐aided identification of T cell and B cell epitopes in the surface glycoprotein of 2019‐nCoV

(2020) Vargab Baruah et al.   JOURNAL OF MEDICAL VIROLOGY

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Critical Review of the Literature on Chest CT and Coronavirus Disease (COVID-19): Data Adjustment

(2020) Tetsuro Sekine   AMERICAN JOURNAL OF ROENTGENOLOGY

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

(2020) Alba Grifoni et al.   CELL

Identification of Human Single-Domain Antibodies against SARS-CoV-2

(2020) Yanling Wu et al.   Cell Host & Microbe

A Dynamic Immune Response Shapes COVID-19 Progression

(2020) Eugenia Ziying Ong et al.   Cell Host & Microbe

Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients

(2020) Xiaohua Chen et al.   CLINICAL INFECTIOUS DISEASES

Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals

(2020) Ling Ni et al.   IMMUNITY

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Human neutralizing antibodies elicited by SARS-CoV-2 infection

(2020) Bin Ju et al.   NATURE

A serological assay to detect SARS-CoV-2 seroconversion in humans

(2020) Fatima Amanat et al.   NATURE MEDICINE

Antibody responses to SARS-CoV-2 in patients with COVID-19

(2020) Quan-Xin Long et al.   NATURE MEDICINE

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

(2020) Abishek Chandrashekar et al.   SCIENCE

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period

(2020) Stephen M. Kissler et al.   SCIENCE

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)

(2020) Bo Diao et al.   Frontiers in Immunology

Potential contribution of increased soluble IL-2R to lymphopenia in COVID-19 patients

(2020) Yaguang Zhang et al.   Cellular & Molecular Immunology

Lessons for COVID-19 Immunity from Other Coronavirus Infections

(2020) Alan Sariol et al.   IMMUNITY

Mild versus severe COVID-19: Laboratory markers

(2020) Thirumalaisamy P. Velavan et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection

(2020) Min Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

(2020) Julian Braun et al.   NATURE

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

(2020) Nina Le Bert et al.   NATURE

Serology assays to manage COVID-19

(2020) Florian Krammer et al.   SCIENCE

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

(2020) Divij Mathew et al.   SCIENCE

Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

(2020) Jose Mateus et al.   SCIENCE

Reappearance of effector T cells is associated with recovery from COVID-19

(2020) Ivan Odak et al.   EBioMedicine

Comprehensive mapping of immune perturbations associated with severe COVID-19

(2020) Leticia Kuri-Cervantes et al.   Science Immunology

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

(2020) Daniela Weiskopf et al.   Science Immunology

Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysis

(2020) Ian Huang et al.   Journal of Intensive Care

The chemokine receptor antagonist cenicriviroc inhibits the replication of SARS-CoV-2 in vitro

(2020) Mika Okamoto et al.   ANTIVIRAL RESEARCH

COVID-19 length of hospital stay: a systematic review and data synthesis

(2020) Eleanor M. Rees et al.   BMC Medicine

What reinfections mean for COVID-19

(2020) Akiko Iwasaki   LANCET INFECTIOUS DISEASES

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

(2020) Yanchun Peng et al.   NATURE IMMUNOLOGY

T cells in COVID-19 — united in diversity

(2020) Leo Swadling et al.   NATURE IMMUNOLOGY

Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans

(2020) Jeffrey Seow et al.   Nature Microbiology

Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients

(2020) Anita S. Iyer et al.   Science Immunology

Strategic Anti-SARS-CoV-2 Serology Testing in a Low Prevalence Setting: The COVID-19 Contact (CoCo) Study in Healthcare Professionals

(2020) Georg M. N. Behrens et al.   Infectious Diseases and Therapy

The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer

(2019) Inna M. Yasinska et al.   Frontiers in Immunology

Role of PD-1 during effector CD8 T cell differentiation

(2018) Eunseon Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overview of the Mechanisms that May Contribute to the Non-Redundant Activities of Interferon-Inducible CXC Chemokine Receptor 3 Ligands

(2018) Mieke Metzemaekers et al.   Frontiers in Immunology

Personalized adoptive immunotherapy for patients with EBV-associated tumors and complications: Evaluation of novel naturally processed and presented EBV-derived T-cell epitopes

(2017) Maren Bieling et al.   Oncotarget

Interferon response of the cystic fibrosis bronchial epithelium to major and minor group rhinovirus infection

(2016) Aline Schögler et al.   Journal of Cystic Fibrosis

Comparative Analysis of Clinical-Scale IFN-γ-Positive T-Cell Enrichment Using Partially and Fully Integrated Platforms

(2016) Christoph Priesner et al.   Frontiers in Immunology

Modulation of heme oxygenase-1 by metalloporphyrins increases anti-viral T cell responses

(2015) C. E. Bunse et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Determination of lymphocyte subset reference ranges in peripheral blood of healthy adults by a dual-platform flow cytometry method

(2015) Renata Cristina Messores Rudolf-Oliveira et al.   IMMUNOLOGY LETTERS

Evaluation of suitable target antigens and immunoassays for high-accuracy immune monitoring of cytomegalovirus and Epstein–Barr virus-specific T cells as targets of interest in immunotherapeutic approaches

(2014) Sabine Tischer et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Clonal Exhaustion as a Mechanism to Protect Against Severe Immunopathology and Death from an Overwhelming CD8 T Cell Response

(2013) Markus Cornberg et al.   Frontiers in Immunology

Differential Virological and Immunological Outcome of Severe Acute Respiratory Syndrome Coronavirus Infection in Susceptible and Resistant Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2

(2009) N. Yoshikawa et al.   JOURNAL OF VIROLOGY

Evasion by Stealth: Inefficient Immune Activation Underlies Poor T Cell Response and Severe Disease in SARS-CoV-Infected Mice

(2009) Jincun Zhao et al.   PLoS Pathogens