Superoxide produced by mitochondrial site IQ inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice

Production of superoxide and hydrogen peroxide in the mitochondrial matrix is dominated by site IQ of complex I in diverse cell lines

(2020) Jingqi Fang et al.   Redox Biology

Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes

(2019) Mark A. Watson et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

S1QELs suppress mitochondrial superoxide/hydrogen peroxide production from site IQ without inhibiting reverse electron flow through Complex I

(2019) Hoi-Shan Wong et al.   FREE RADICAL BIOLOGY AND MEDICINE

The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production

(2019) Renata L.S. Goncalves et al.   Redox Biology

Mitochondrial and cytosolic sources of hydrogen peroxide in resting C2C12 myoblasts

(2018) Hoi-Shan Wong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions

(2017) Hoi-Shan Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Succinate metabolism: a new therapeutic target for myocardial reperfusion injury

(2016) Victoria R. Pell et al.   CARDIOVASCULAR RESEARCH

Suppressors of Superoxide-H 2 O 2 Production at Site I Q of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury

(2016) Martin D. Brand et al.   Cell Metabolism

Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling

(2016) Martin D. Brand   FREE RADICAL BIOLOGY AND MEDICINE

Suppressors of superoxide production from mitochondrial complex III

(2015) Adam L Orr et al.   Nature Chemical Biology

Production of superoxide/H2O2 by dihydroorotate dehydrogenase in rat skeletal muscle mitochondria

(2014) Martin Hey-Mogensen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sites of Superoxide and Hydrogen Peroxide Production by Muscle Mitochondria Assessedex Vivounder Conditions Mimicking Rest and Exercise

(2014) Renata L. S. Goncalves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 2-Oxoacid Dehydrogenase Complexes in Mitochondria Can Produce Superoxide/Hydrogen Peroxide at Much Higher Rates Than Complex I

(2014) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening

(2013) Adam L. Orr et al.   FREE RADICAL BIOLOGY AND MEDICINE

Classical catalase: Ancient and modern

(2012) Peter Nicholls   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters

(2012) Casey L. Quinlan et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Refined Analysis of Superoxide Production by Mitochondrialsn-Glycerol 3-Phosphate Dehydrogenase

(2012) Adam L. Orr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

(2012) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Manganese superoxide dismutase, MnSOD and its mimics

(2011) Sumitra Miriyala et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial H2O2 generated from electron transport chain complex I stimulates muscle differentiation

(2011) Seonmin Lee et al.   CELL RESEARCH

Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice

(2011) James M. Flynn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Manganese Superoxide Dismutase: Guardian of the Powerhouse

(2011) Aaron K. Holley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Mechanism of Superoxide Production by the Antimycin-inhibited Mitochondrial Q-cycle

(2011) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for Two Sites of Superoxide Production by Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I)

(2011) Jason R. Treberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The sites and topology of mitochondrial superoxide production

(2010) Martin D. Brand   EXPERIMENTAL GERONTOLOGY

Succinate dehydrogenase – Assembly, regulation and role in human disease

(2010) Jared Rutter et al.   MITOCHONDRION

Human catalase: looking for complete identity

(2010) Madhur M. Goyal et al.   Protein & Cell

Mitochondria and reactive oxygen species

(2009) Alicia J. Kowaltowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation

(2009) Erich B. Tahara et al.   FREE RADICAL BIOLOGY AND MEDICINE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

ΔΨm-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

(2003) Tatyana V. Votyakova et al.   JOURNAL OF NEUROCHEMISTRY