Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes

Protection against cardiac ischemia-reperfusion injury by hypothermia and by inhibition of succinate accumulation and oxidation is additive

(2019) M. Kohlhauer et al.   BASIC RESEARCH IN CARDIOLOGY

Potential of Mitochondria-Targeted Antioxidants to Prevent Oxidative Stress in Pancreatic β-cells

(2019) Lydie Plecitá-Hlavatá et al.   Oxidative Medicine and Cellular Longevity

Regulation of succinate dehydrogenase and role of succinate in cancer

(2019) Elisa Dalla Pozza et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals

(2019) Dominique Detaille et al.   PLoS One

Effect of Particulate Matter Air Pollution on Cardiovascular Oxidative Stress Pathways

(2018) Xiaoquan Rao et al.   ANTIOXIDANTS & REDOX SIGNALING

Are Hydroethidine-Based Probes Reliable for Reactive Oxygen Species Detection?

(2018) Yi Xiao et al.   ANTIOXIDANTS & REDOX SIGNALING

Endoplasmic Reticulum Stress signalling - from basic mechanisms to clinical applications

(2018) Aitor Almanza et al.   FEBS Journal

Inflammatory health effects of indoor and outdoor particulate matter

(2018) Weidong Wu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Control of mitochondrial superoxide production by reverse electron transport at complex I

(2018) Ellen L. Robb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells

(2018) Marine Oberkampf et al.   Nature Communications

Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis

(2018) Saul Soberanes et al.   Cell Metabolism

Mitochondrial and cytosolic sources of hydrogen peroxide in resting C2C12 myoblasts

(2018) Hoi-Shan Wong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions

(2017) Hoi-Shan Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial ROS control of cancer

(2017) María del Pilar Sosa Idelchik et al.   SEMINARS IN CANCER BIOLOGY

Understanding and preventing mitochondrial oxidative damage

(2016) Michael P. Murphy   BIOCHEMICAL SOCIETY TRANSACTIONS

Suppressors of Superoxide-H 2 O 2 Production at Site I Q of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury

(2016) Martin D. Brand et al.   Cell Metabolism

A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury

(2016) Edward T. Chouchani et al.   Cell Metabolism

Redox signaling: An evolution from free radicals to aging

(2016) Henry Jay Forman   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling

(2016) Martin D. Brand   FREE RADICAL BIOLOGY AND MEDICINE

Endoplasmic Reticulum Stress and Associated ROS

(2016) Hafiz Zeeshan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Calcium and mitochondria in the regulation of cell death

(2015) Sten Orrenius et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Respective effects of oxygen and energy substrate deprivation on beta cell viability

(2015) Sandrine Lablanche et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Suppressors of superoxide production from mitochondrial complex III

(2015) Adam L Orr et al.   Nature Chemical Biology

Protection against renal ischemia–reperfusion injury in vivo by the mitochondria targeted antioxidant MitoQ

(2015) Anna J. Dare et al.   Redox Biology

HIF-1α pathway: role, regulation and intervention for cancer therapy

(2015) Georgina N. Masoud et al.   Acta Pharmaceutica Sinica B

Sites of Superoxide and Hydrogen Peroxide Production by Muscle Mitochondria Assessedex Vivounder Conditions Mimicking Rest and Exercise

(2014) Renata L. S. Goncalves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

(2014) Dmitry B. Zorov et al.   PHYSIOLOGICAL REVIEWS

Longitudinal study of respiratory function and symptoms in a non-smoking group of long-term officially-acknowledged victims of pollution-related illness

(2013) Takako Tanaka et al.   BMC PUBLIC HEALTH

Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I

(2013) Edward T Chouchani et al.   NATURE MEDICINE

Mitochondrial reactive oxygen species generation triggers inflammatory response and tissue injury associated with hepatic ischemia–reperfusion: Therapeutic potential of mitochondrially targeted antioxidants

(2012) Partha Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Oxygen Free Radicals Originating from Mitochondrial Complex I Contribute to Oxidative Brain Injury Following Hypoxia-Ischemia in Neonatal Mice

(2012) Z. V. Niatsetskaya et al.   JOURNAL OF NEUROSCIENCE

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

A Novel Murine Model of Inflammatory Bowel Disease and Inflammation-Associated Colon Cancer with Ulcerative Colitis-Like Features

(2012) Laura P. Hale et al.   PLoS One

Unraveling the Biological Roles of Reactive Oxygen Species

(2011) Michael P. Murphy et al.   Cell Metabolism

CD8+ T Cells: Foot Soldiers of the Immune System

(2011) Nu Zhang et al.   IMMUNITY

Evidence for Two Sites of Superoxide Production by Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I)

(2011) Jason R. Treberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Prevention of diabetic nephropathy in Ins2+/−AkitaJmice by the mitochondria-targeted therapy MitoQ

(2010) Balu K. Chacko et al.   BIOCHEMICAL JOURNAL

Mitochondrial oxidant stress triggers cell death in simulated ischemia–reperfusion

(2010) Gabriel Loor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model

(2010) Anamitra Ghosh et al.   FREE RADICAL BIOLOGY AND MEDICINE

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

(2010) Edward J. Gane et al.   LIVER INTERNATIONAL

MitoQ administration prevents endotoxin-induced cardiac dysfunction

(2009) G. S. Supinski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

(2009) Huaqi Jiang et al.   CELL

Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy

(2009) Delyth Graham et al.   HYPERTENSION

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation

(2008) J. Mouries et al.   BLOOD

Antigen-Presentation Properties of Plasmacytoid Dendritic Cells

(2008) José A. Villadangos et al.   IMMUNITY

Protective Effects of Mitochondria-Targeted Antioxidant SkQ in Aqueous and Lipid Membrane Environments

(2008) Y. N. Antonenko et al.   JOURNAL OF MEMBRANE BIOLOGY