Zebrafish as an animal model for biomedical research

REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects

(2020) Shin-Haw Lee et al.   Nature Communications

Plasma Membrane Furrows Control Plasticity of ER-PM Contacts

(2020) Annabel Qi En Ng et al.   Cell Reports

Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy

(2020) Yu-Ri Lee et al.   Nature Communications

Modeling Lysosomal Storage Diseases in the Zebrafish

(2020) T. Zhang et al.   Frontiers in Molecular Biosciences

The Rab11 effectors Fip5 and Fip1 regulate zebrafish intestinal development

(2020) Cayla E. Jewett et al.   Biology Open

Anti-Obesity Natural Products Tested in Juvenile Zebrafish Obesogenic Tests and Mouse 3T3-L1 Adipogenesis Assays

(2020) Hiroko Nakayama et al.   MOLECULES

Sorting out microtubule-based transport

(2020) Ahmet Yildiz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism

(2019) Danni Chen et al.   NUCLEIC ACIDS RESEARCH

Targeted knockout of duox causes defects in zebrafish growth, thyroid development, and social interaction

(2019) Jong-Su Park et al.   Journal of Genetics and Genomics

Dissecting metabolism using zebrafish models of disease

(2019) Talhah M. Salmi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The epg5 knockout zebrafish line: a model to study Vici syndrome

(2019) Giacomo Meneghetti et al.   Autophagy

Knock-In Strategy for Editing Human and Zebrafish Mitochondrial DNA Using Mito-CRISPR/Cas9 System

(2019) Wan-Ping Bian et al.   ACS Synthetic Biology

Slc25a17 acts as a peroxisomal coenzyme A transporter and regulates multiorgan development in zebrafish

(2019) Yong‐Il Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dysregulation in the Brain Protein Profile of Zebrafish Lacking the Parkinson’s Disease-Related Protein DJ-1

(2019) Amanda J. Edson et al.   MOLECULAR NEUROBIOLOGY

Role of β-glucosidase 2 in aberrant glycosphingolipid metabolism: model of glucocerebrosidase deficiency in zebrafish

(2019) Lindsey T. Lelieveld et al.   JOURNAL OF LIPID RESEARCH

Restriction of mitochondrial calcium overload by mcu inactivation renders neuroprotective effect in Zebrafish models of Parkinson's disease

(2019) Smijin K. Soman et al.   Biology Open

A network-based approach to identify deregulated pathways and drug effects in metabolic syndrome

(2019) Karla Misselbeck et al.   Nature Communications

Black Raspberry (Rubus coreanus Miquel) Promotes Browning of Preadipocytes and Inguinal White Adipose Tissue in Cold-Induced Mice

(2019) Woo Yong Park et al.   Nutrients

Fish as a model to assess chemical toxicity in bone

(2018) Ignacio Fernández et al.   AQUATIC TOXICOLOGY

The neurological toxicity of heavy metals: A fish perspective

(2018) Adrian J. Green et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Neutrophil-specific knockout demonstrates a role for mitochondria in regulating neutrophil motility in zebrafish

(2018) Wenqing Zhou et al.   Disease Models & Mechanisms

Targeted knockout of a chemokine-like gene increases anxiety and fear responses

(2018) Jung-Hwa Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms

(2018) Tsung-Li Liu et al.   SCIENCE

Making Waves: New Developments in Toxicology With the Zebrafish

(2018) Katharine A Horzmann et al.   TOXICOLOGICAL SCIENCES

Modeling Niemann-Pick disease type C1 in zebrafish: a robust platform forin vivoscreening of candidate therapeutic compounds

(2018) Wei-Chia Tseng et al.   Disease Models & Mechanisms

Nucleoside supplementation modulates mitochondrial DNA copy number in the dguok -/- zebrafish

(2018) Benjamin Munro et al.   HUMAN MOLECULAR GENETICS

Novel Anti-Obesity Properties of Palmaria mollis in Zebrafish and Mouse Models

(2018) Hiroko Nakayama et al.   Nutrients

Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes

(2017) Ayumu Sugiura et al.   NATURE

Deficiency of a brain-specific chemokine-like molecule, SAM3, induces cardinal phenotypes of autism spectrum disorders in mice

(2017) Sujin Kim et al.   Scientific Reports

Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase

(2016) Tomoyuki Sasaki et al.   Autophagy

Zebrafish Tg(hb9:MTS-Kaede): a new in vivo tool for studying the axonal movement of mitochondria

(2016) Giorgia Bergamin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Central Nervous System and the Gut Microbiome

(2016) Gil Sharon et al.   CELL

Fis1 depletion in osteoarthritis impairs chondrocyte survival and peroxisomal and lysosomal function

(2016) Dongkyun Kim et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Imaging Subcellular Structures in the Living Zebrafish Embryo

(2016) Peter Engerer et al.   Jove-Journal of Visualized Experiments

Metabolic insights from zebrafish genetics, physiology, and chemical biology

(2015) Amnon Schlegel et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons

(2015) Melanie May et al.   HUMAN MOLECULAR GENETICS

European Consensus Statement on congenital hypogonadotropic hypogonadism—pathogenesis, diagnosis and treatment

(2015) Ulrich Boehm et al.   Nature Reviews Endocrinology

Endothelial Ca2+ oscillations reflect VEGFR signaling-regulated angiogenic capacity in vivo

(2015) Yasuhiro Yokota et al.   eLife

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Zebrafish Model in Drug Safety Assessment

(2014) Jyotshna Kanungo et al.   CURRENT PHARMACEUTICAL DESIGN

Neutralization of Mitochondrial Superoxide by Superoxide Dismutase 2 Promotes Bacterial Clearance and Regulates Phagocyte Numbers in Zebrafish

(2014) E. M. Peterman et al.   INFECTION AND IMMUNITY

Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease

(2014) Un Jung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In vivo cell biology in zebrafish - providing insights into vertebrate development and disease

(2014) A. M. Vacaru et al.   JOURNAL OF CELL SCIENCE

Zebrafish as a model to explore cell metabolism

(2014) Massimo M. Santoro   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Transgenic zebrafish for ratiometric imaging of cytosolic and mitochondrial Ca2+ response in teleost embryo

(2013) Hideaki Mizuno et al.   CELL CALCIUM

Zebrafish: A Multifaceted Tool for Chemical Biologists

(2013) Sandeep Basu et al.   CHEMICAL REVIEWS

The expanding role of fish models in understanding non-alcoholic fatty liver disease

(2013) Y. Asaoka et al.   Disease Models & Mechanisms

The emerging use of zebrafish to model metabolic disease

(2013) A. Seth et al.   Disease Models & Mechanisms

Use of zebrafish apoptosis assays for preclinical drug discovery

(2013) Patricia McGrath et al.   Expert Opinion on Drug Discovery

Extensive Conversion of Hepatic Biliary Epithelial Cells to Hepatocytes After Near Total Loss of Hepatocytes in Zebrafish

(2013) Tae–Young Choi et al.   GASTROENTEROLOGY

Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases

(2013) Y. H. Sung et al.   GENOME RESEARCH

Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis

(2013) Kathryn Ellis et al.   JOURNAL OF CELL BIOLOGY

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Translocations Disrupting PHF21A in the Potocki-Shaffer-Syndrome Region Are Associated with Intellectual Disability and Craniofacial Anomalies

(2012) Hyung-Goo Kim et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Generation of transgenic zebrafish with liver-specific expression of EGFP-Lc3: A new in vivo model for investigation of liver autophagy

(2012) Jianzhou Cui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dynamic microtubules at the vegetal cortex predict the embryonic axis in zebrafish

(2012) L. D. Tran et al.   DEVELOPMENT

In vivo genome editing using a high-efficiency TALEN system

(2012) Victoria M. Bedell et al.   NATURE

The Cx43-like Connexin Protein Cx40.8 Is Differentially Localized during Fin Ontogeny and Fin Regeneration

(2012) Sarah V. Gerhart et al.   PLoS One

Acute Inflammation Initiates the Regenerative Response in the Adult Zebrafish Brain

(2012) N. Kyritsis et al.   SCIENCE

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Analysis of KIF17 distal tip trafficking in zebrafish cone photoreceptors

(2012) Jason R. Bader et al.   VISION RESEARCH

Generation of Rab-based transgenic lines for in vivo studies of endosome biology in zebrafish

(2011) Brian S. Clark et al.   DEVELOPMENTAL DYNAMICS

WDR11, a WD Protein that Interacts with Transcription Factor EMX1, Is Mutated in Idiopathic Hypogonadotropic Hypogonadism and Kallmann Syndrome

(2010) Hyung-Goo Kim et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Atypical Protein Kinase C Regulates Primary Dendrite Specification of Cerebellar Purkinje Cells by Localizing Golgi Apparatus

(2010) K. Tanabe et al.   JOURNAL OF NEUROSCIENCE

Genomewide Association Studies and Assessment of the Risk of Disease

(2010) Teri A. Manolio   NEW ENGLAND JOURNAL OF MEDICINE

Epithelial cell proliferation in the developing zebrafish intestine is regulated by the Wnt pathway and microbial signaling via Myd88

(2010) S. E. Cheesman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-linked intellectual disability: Unique vulnerability of the male genome

(2009) Roger E. Stevenson et al.   Developmental Disabilities Research Reviews

Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio)

(2009) Edward J. Flynn et al.   JOURNAL OF LIPID RESEARCH

Real-time imaging of mitochondria in transgenic zebrafish expressing mitochondrially targeted GFP

(2008) Min Jung Kim et al.   BIOTECHNIQUES

Live Imaging of Neuronal Degradation by Microglia Reveals a Role for v0-ATPase a1 in Phagosomal Fusion In Vivo

(2008) Francesca Peri et al.   CELL

Zebrafish: a predictive model for assessing drug-induced toxicity

(2008) Patricia McGrath et al.   DRUG DISCOVERY TODAY

Hypothalamic Control of Anterior Pituitary Function: A History

(2008) H. Charlton   JOURNAL OF NEUROENDOCRINOLOGY

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

(2008) Yannick Doyon et al.   NATURE BIOTECHNOLOGY

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

(2008) Xiangdong Meng et al.   NATURE BIOTECHNOLOGY

Gal4/UAS Transgenic Tools and Their Application to Zebrafish

(2008) Marnie E. Halpern et al.   Zebrafish