European Consensus Statement on congenital hypogonadotropic hypogonadism—pathogenesis, diagnosis and treatment
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
European Consensus Statement on congenital hypogonadotropic hypogonadism—pathogenesis, diagnosis and treatment
Authors
Keywords
-
Journal
Nature Reviews Endocrinology
Volume 11, Issue 9, Pages 547-564
Publisher
Springer Nature
Online
2015-07-21
DOI
10.1038/nrendo.2015.112
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Gonadotrophin replacement for induction of fertility in hypogonadal men
- (2015) Andrew A. Dwyer et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- TRANSITION IN ENDOCRINOLOGY: Hypogonadism in adolescence
- (2015) A. A. Dwyer et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- A Shared Genetic Basis for Self-Limited Delayed Puberty and Idiopathic Hypogonadotropic Hypogonadism
- (2015) Jia Zhu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Evaluation of 451 Danish Boys With Delayed Puberty: Diagnostic Use of a New Puberty Nomogram and Effects of Oral Testosterone Therapy
- (2015) Jacob Gerner Lawaetz et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Mutations in FEZF1 Cause Kallmann Syndrome
- (2014) L. Damla Kotan et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Childhood growth of females with Kallmann syndrome andFGFR1mutations
- (2014) Matti Hero et al. CLINICAL ENDOCRINOLOGY
- Inhibin B plus LHvsGnRH agonist test for distinguishing constitutional delay of growth and puberty from isolated hypogonadotropic hypogonadism in boys
- (2014) Gerhard Binder et al. CLINICAL ENDOCRINOLOGY
- Assessment of quality of life during gonadotrophin treatment for male hypogonadotrophic hypogonadism
- (2014) Koji Shiraishi et al. CLINICAL ENDOCRINOLOGY
- Disparate Changes in Kisspeptin and Neurokinin B Expression in the Arcuate Nucleus After Sex Steroid Manipulation Reveal Differential Regulation of the Two KNDy Peptides in Rats
- (2014) Agnete Overgaard et al. ENDOCRINOLOGY
- TRANSITION IN ENDOCRINOLOGY: Induction of puberty
- (2014) Leo Dunkel et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Physiological Estrogen Replacement Therapy for Puberty Induction in Girls: A Clinical Observational Study
- (2014) Carina Ankarberg-Lindgren et al. Hormone Research in Paediatrics
- Loss-of-Function Mutations inPNPLA6Encoding Neuropathy Target Esterase Underlie Pubertal Failure and Neurological Deficits in Gordon Holmes Syndrome
- (2014) A. Kemal Topaloglu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Anti-Mullerian Hormone Deficiency in Girls With Congenital Multiple Pituitary Hormone Deficiency
- (2014) Beate Deubzer et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Exogenous Kisspeptin Administration as a Probe of GnRH Neuronal Function in Patients With Idiopathic Hypogonadotropic Hypogonadism
- (2014) Yee-Ming Chan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The Prevalence ofCHD7Missense Versus Truncating Mutations Is Higher in Patients With Kallmann Syndrome Than in Typical CHARGE Patients
- (2014) Séverine Marcos et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction
- (2014) Nicole Bellefontaine et al. JOURNAL OF CLINICAL INVESTIGATION
- Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilization
- (2014) Channa N. Jayasena et al. JOURNAL OF CLINICAL INVESTIGATION
- Murine Arcuate Nucleus Kisspeptin Neurons Communicate with GnRH Neurons In Utero
- (2014) D. Kumar et al. JOURNAL OF NEUROSCIENCE
- Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
- (2014) John R. B. Perry et al. NATURE
- Transition of care for adolescents with disorders of sex development
- (2014) Naomi S. Crouch et al. Nature Reviews Endocrinology
- Genotype–Phenotype Correlation — Promiscuity in the Era of Next-Generation Sequencing
- (2014) James T. Lu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Extensive clinical, hormonal and genetic screening in a large consecutive series of 46,XY neonates and infants with atypical sexual development
- (2014) Dorien Baetens et al. Orphanet Journal of Rare Diseases
- Identifying the unmet health needs of patients with congenital hypogonadotropic hypogonadism using a web-based needs assessment: implications for online interventions and peer-to-peer support
- (2014) Andrew A Dwyer et al. Orphanet Journal of Rare Diseases
- De novo SOX10 nonsense mutation in a patient with Kallmann syndrome and hearing loss
- (2014) Kirsi Vaaralahti et al. PEDIATRIC RESEARCH
- Mutation screening of SEMA3A and SEMA7A in patients with congenital hypogonadotropic hypogonadism
- (2014) Johanna Känsäkoski et al. PEDIATRIC RESEARCH
- Testosterone, Sex Hormone-Binding Globulin and the Metabolic Syndrome in Men: An Individual Participant Data Meta-Analysis of Observational Studies
- (2014) Judith S. Brand et al. PLoS One
- Functionally compromisedCHD7alleles in patients with isolated GnRH deficiency
- (2014) Ravikumar Balasubramanian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Serum levels of insulin-like factor 3, anti-Müllerian hormone, inhibin B, and testosterone during pubertal transition in healthy boys: a longitudinal pilot study
- (2014) Marie Lindhardt Johansen et al. REPRODUCTION
- Haploinsufficiency of Dmxl2, Encoding a Synaptic Protein, Causes Infertility Associated with a Loss of GnRH Neurons in Mouse
- (2014) Brooke Tata et al. PLOS BIOLOGY
- Factors affecting spermatogenesis upon gonadotropin-replacement therapy: a meta-analytic study
- (2014) G. Rastrelli et al. Andrology
- Systematic literature review of the risk factors, comorbidities, and consequences of hypogonadism in men
- (2014) V. Zarotsky et al. Andrology
- Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 Are Identified in Individuals with Congenital Hypogonadotropic Hypogonadism
- (2013) Hichem Miraoui et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Loss-of-Function Mutations in SOX10 Cause Kallmann Syndrome with Deafness
- (2013) Veronique Pingault et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Impaired emotional state, quality of life and cognitive functions in young hypogonadal men
- (2013) L. Lašaitė et al. ANDROLOGIA
- PNPLA6 mutations cause Boucher-Neuhäuser and Gordon Holmes syndromes as part of a broad neurodegenerative spectrum
- (2013) Matthis Synofzik et al. BRAIN
- Reversal of isolated hypogonadotropic hypogonadism: long-term integrity of hypothalamo-pituitary-testicular axis in two men is dependent on intermittent androgen exposure
- (2013) Anjali Santhakumar et al. CLINICAL ENDOCRINOLOGY
- Pubertal induction in adult males with isolated hypogonadotropic hypogonadism using long-acting intramuscular testosterone undecanoate 1-g depot (Nebido®)
- (2013) Anjali Santhakumar et al. CLINICAL ENDOCRINOLOGY
- Custom oligonucleotide array-based CGH: a reliable diagnostic tool for detection of exonic copy-number changes in multiple targeted genes
- (2013) Aurélie Vasson et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Trial of Recombinant Follicle-Stimulating Hormone Pretreatment for GnRH-Induced Fertility in Patients with Congenital Hypogonadotropic Hypogonadism
- (2013) Andrew A. Dwyer et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Approach to the Patient With Hypogonadotropic Hypogonadism
- (2013) Letícia Ferreira Gontijo Silveira et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Prioritizing Genetic Testing in Patients With Kallmann Syndrome Using Clinical Phenotypes
- (2013) Flavia Amanda Costa-Barbosa et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Approach to Male Infertility and Induction of Spermatogenesis
- (2013) Bradley D. Anawalt JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Responsiveness to a Physiological Regimen of GnRH Therapy and Relation to Genotype in Women With Isolated Hypogonadotropic Hypogonadism
- (2013) Brent S. Abel et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Insulin-like Peptide 3 (INSL3) in Men With Congenital Hypogonadotropic Hypogonadism/Kallmann Syndrome and Effects of Different Modalities of Hormonal Treatment: A Single-Center Study of 281 Patients
- (2013) Séverine Trabado et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Reversal and Relapse of Hypogonadotropic Hypogonadism: Resilience and Fragility of the Reproductive Neuroendocrine System
- (2013) Valerie F. Sidhoum et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Ataxia, Dementia, and Hypogonadotropism Caused by Disordered Ubiquitination
- (2013) David H. Margolin et al. NEW ENGLAND JOURNAL OF MEDICINE
- Fertility Treatments and Multiple Births in the United States
- (2013) Aniket D. Kulkarni et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ideal timing of orchiopexy: a systematic review
- (2013) Emily Chan et al. PEDIATRIC SURGERY INTERNATIONAL
- Effectiveness of Hormonal and Surgical Therapies for Cryptorchidism: A Systematic Review
- (2013) D. Penson et al. PEDIATRICS
- Onset of Breast Development in a Longitudinal Cohort
- (2013) F. M. Biro et al. PEDIATRICS
- Congenital Hypogonadotropic Hypogonadism during Childhood: Presentation and Genetic Analyses in 46 Boys
- (2013) Audrey Vizeneux et al. PLoS One
- The prepubertal testis
- (2013) Clara Valeri et al. Current Opinion in Endocrinology Diabetes and Obesity
- Micropenis: Etiology, Diagnosis and Treatment Approaches
- (2013) Hatipoğlu Nihal et al. Journal of Clinical Research in Pediatric Endocrinology
- Management of anovulatory infertility
- (2012) Raymond Hang Wun Li et al. BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
- A homozygous R262Q mutation in the gonadotropin-releasing hormone receptor presenting as reversal of hypogonadotropic hypogonadism and late-onset hypogonadism
- (2012) Johanna Tommiska et al. CLINICAL ENDOCRINOLOGY
- Extracellular Matrix Protein Anosmin Promotes Neural Crest Formation and Regulates FGF, BMP, and WNT Activities
- (2012) Yukinori Endo et al. DEVELOPMENTAL CELL
- Increased frequency of anxiety, depression, quality of life and sexual life in young hypogonadotropic hypogonadal males and impacts of testosterone replacement therapy on these conditions
- (2012) Umit Aydogan et al. ENDOCRINE JOURNAL
- Glutamatergic and GABAergic Innervation of Human Gonadotropin-Releasing Hormone-I Neurons
- (2012) Erik Hrabovszky et al. ENDOCRINOLOGY
- Transition from Pediatric to Adult Healthcare: Assessment of Specific Needs of Patients with Chronic Endocrine Conditions
- (2012) Ariane Godbout et al. Hormone Research in Paediatrics
- SEMA3A deletion in a family with Kallmann syndrome validates the role of semaphorin 3A in human puberty and olfactory system development
- (2012) Jacques Young et al. HUMAN REPRODUCTION
- Bone mineral density, body composition and bone turnover in patients with congenital hypogonadotropic hypogonadism
- (2012) E.-M. Laitinen et al. INTERNATIONAL JOURNAL OF ANDROLOGY
- Approach to the Male Patient with Congenital Hypogonadotropic Hypogonadism
- (2012) Jacques Young JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Distinguishing Constitutional Delay of Growth and Puberty from Isolated Hypogonadotropic Hypogonadism: Critical Appraisal of Available Diagnostic Tests
- (2012) Jennifer Harrington et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Osteoprotection by semaphorin 3A
- (2012) Mikihito Hayashi et al. NATURE
- Kisspeptin Restores Pulsatile LH Secretion in Patients with Neurokinin B Signaling Deficiencies: Physiological, Pathophysiological and Therapeutic Implications
- (2012) Jacques Young et al. NEUROENDOCRINOLOGY
- InactivatingKISS1Mutation and Hypogonadotropic Hypogonadism
- (2012) A. Kemal Topaloglu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Delayed Puberty
- (2012) Mark R. Palmert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Secondary Sexual Characteristics in Boys: Data From the Pediatric Research in Office Settings Network
- (2012) M. E. Herman-Giddens et al. PEDIATRICS
- Kisspeptins and Reproduction: Physiological Roles and Regulatory Mechanisms
- (2012) Leonor Pinilla et al. PHYSIOLOGICAL REVIEWS
- Reversible Congenital Hypogonadotropic Hypogonadism in Patients with CHD7, FGFR1 or GNRHR Mutations
- (2012) Eeva-Maria Laitinen et al. PLoS One
- SEMA3A, a Gene Involved in Axonal Pathfinding, Is Mutated in Patients with Kallmann Syndrome
- (2012) Naresh Kumar Hanchate et al. PLoS Genetics
- Fertility potential in men with a history of congenital undescended testes: a long-term follow-up study
- (2012) J. van Brakel et al. Andrology
- Male hypogonadism: an extended classification based on a developmental, endocrine physiology-based approach
- (2012) R. A. Rey et al. Andrology
- The Role of the Prokineticin 2 Pathway in Human Reproduction: Evidence from the Study of Human and Murine Gene Mutations
- (2011) Cecilia Martin et al. ENDOCRINE REVIEWS
- The prevalence of digenic mutations in patients with normosmic hypogonadotropic hypogonadism and Kallmann syndrome
- (2011) Samuel D. Quaynor et al. FERTILITY AND STERILITY
- FRAX® International Task Force of the 2010 Joint International Society for Clinical Densitometry & International Osteoporosis Foundation Position Development Conference
- (2011) Jane A. Cauley et al. JOURNAL OF CLINICAL DENSITOMETRY
- GnRH-Deficient Phenotypes in Humans and Mice with Heterozygous Variants inKISS1/Kiss1
- (2011) Yee-Ming Chan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Expanding the Phenotype and Genotype of Female GnRH Deficiency
- (2011) Natalie D. Shaw et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Postnatal Developmental Changes in the Pituitary-Ovarian Axis in Preterm and Term Infant Girls
- (2011) Tanja Kuiri-Hänninen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Olfactory Phenotypic Spectrum in Idiopathic Hypogonadotropic Hypogonadism: Pathophysiological and Genetic Implications
- (2011) Hilana M. Lewkowitz-Shpuntoff et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Neural Crest and Ectodermal Cells Intermix in the Nasal Placode to Give Rise to GnRH-1 Neurons, Sensory Neurons, and Olfactory Ensheathing Cells
- (2011) P. E. Forni et al. JOURNAL OF NEUROSCIENCE
- Role of fibroblast growth factor (FGF) signaling in the neuroendocrine control of human reproduction
- (2011) Hichem Miraoui et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Genetic counseling for isolated GnRH deficiency
- (2011) Margaret G. Au et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Neonatal gonadotropin therapy in male congenital hypogonadotropic hypogonadism
- (2011) Claire Bouvattier et al. Nature Reviews Endocrinology
- Neuroendocrine control by kisspeptins: role in metabolic regulation of fertility
- (2011) Victor M. Navarro et al. Nature Reviews Endocrinology
- Incidence, Phenotypic Features and Molecular Genetics of Kallmann Syndrome in Finland
- (2011) Eeva-Maria Laitinen et al. Orphanet Journal of Rare Diseases
- Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism
- (2011) J. Tornberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- WDR11, a WD Protein that Interacts with Transcription Factor EMX1, Is Mutated in Idiopathic Hypogonadotropic Hypogonadism and Kallmann Syndrome
- (2010) Hyung-Goo Kim et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Clues to an early diagnosis of Kallmann syndrome
- (2010) Julie D. Kaplan et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Clinical genetics of Kallmann syndrome
- (2010) C. Dodé et al. ANNALES D ENDOCRINOLOGIE
- Growth and Development of Male External Genitalia
- (2010) Analia Tomova et al. ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE
- Unilateral renal aplasia in X-linked Kallmann's syndrome
- (2010) J. M. W. Kirk et al. CLINICAL GENETICS
- Twice-Weekly Administration of Kisspeptin-54 for 8 Weeks Stimulates Release of Reproductive Hormones in Women With Hypothalamic Amenorrhea
- (2010) C N Jayasena et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Type 2 diabetes mellitus and testosterone: a meta-analysis study
- (2010) G. Corona et al. INTERNATIONAL JOURNAL OF ANDROLOGY
- Testosterone, sex hormone-binding globulin and the metabolic syndrome: a systematic review and meta-analysis of observational studies
- (2010) J. S. Brand et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Dental agenesis in Kallmann syndrome individuals with FGFR1 mutations
- (2010) ISABELLE BAILLEUL-FORESTIER et al. International Journal of Paediatric Dentistry
- TAC3/TACR3Mutations Reveal Preferential Activation of Gonadotropin-Releasing Hormone Release by Neurokinin B in Neonatal Life Followed by Reversal in Adulthood
- (2010) Elena Gianetti et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Congenital Idiopathic Hypogonadotropic Hypogonadism: Evidence of Defects in the Hypothalamus, Pituitary, and Testes
- (2010) Gerasimos P. Sykiotis et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Nonsense Mutations inFGF8Gene Causing Different Degrees of Human Gonadotropin-Releasing Deficiency
- (2010) Ericka B. Trarbach et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Baseline Inhibin B and Anti-Mullerian Hormone Measurements for Diagnosis of Hypogonadotropic Hypogonadism (HH) in Boys with Delayed Puberty
- (2010) Régis Coutant et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- TAC3andTACR3Defects Cause Hypothalamic Congenital Hypogonadotropic Hypogonadism in Humans
- (2010) Jacques Young et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Serum Levels of Anti-Müllerian Hormone as a Marker of Ovarian Function in 926 Healthy Females from Birth to Adulthood and in 172 Turner Syndrome Patients
- (2010) Casper P. Hagen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Changes in Anti-Müllerian Hormone (AMH) throughout the Life Span: A Population-Based Study of 1027 Healthy Males from Birth (Cord Blood) to the Age of 69 Years
- (2010) L. Aksglaede et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Testosterone Therapy in Men with Androgen Deficiency Syndromes: An Endocrine Society Clinical Practice Guideline
- (2010) Shalender Bhasin et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Increased Activity of the Hypothalamic-Pituitary-Testicular Axis in Infancy Results in Increased Androgen Action in Premature Boys
- (2010) Tanja Kuiri-Hänninen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Defective migration of neuroendocrine GnRH cells in human arrhinencephalic conditions
- (2010) Luis Teixeira et al. JOURNAL OF CLINICAL INVESTIGATION
- Leptin’s effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons
- (2010) Jose Donato et al. JOURNAL OF CLINICAL INVESTIGATION
- Oligogenic basis of isolated gonadotropin-releasing hormone deficiency
- (2010) G. P. Sykiotis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Timing and completion of puberty in female mice depend on estrogen receptor -signaling in kisspeptin neurons
- (2010) C. Mayer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quality assessment of induced spermatogenesis in hypogonadotrophic hypogonadic men treated with gonadotrophins
- (2010) K. Krabchi et al. REPRODUCTIVE BIOMEDICINE ONLINE
- What is the optimal therapy for young males with hypogonadotropic hypogonadism?
- (2009) T. S. Han et al. CLINICAL ENDOCRINOLOGY
- CHD7mutations in patients initially diagnosed with Kallmann syndrome - the clinical overlap with CHARGE syndrome
- (2009) MCJ Jongmans et al. CLINICAL GENETICS
- Leptin Indirectly Regulates Gonadotropin-Releasing Hormone Neuronal Function
- (2009) Janette H. Quennell et al. ENDOCRINOLOGY
- Acquired cryptorchidism is frequent in infancy and childhood
- (2009) Christine Wohlfahrt-Veje et al. INTERNATIONAL JOURNAL OF ANDROLOGY
- A Comparative Phenotypic Study of Kallmann Syndrome Patients Carrying Monoallelic and Biallelic Mutations in the Prokineticin 2 or Prokineticin Receptor 2 Genes
- (2009) Julie Sarfati et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Recent Changes in Pubertal Timing in Healthy Danish Boys: Associations with Body Mass Index
- (2009) Kaspar Sørensen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Oestrogen, Kisspeptin, GPR54 and the Pre-Ovulatory Luteinising Hormone Surge
- (2009) J. Clarkson et al. JOURNAL OF NEUROENDOCRINOLOGY
- Ontogeny of the androgen receptor expression in the fetal and postnatal testis: Its relevance on Sertoli cell maturation and the onset of adult spermatogenesis
- (2009) Rodolfo A. Rey et al. MICROSCOPY RESEARCH AND TECHNIQUE
- The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism
- (2009) Suzy D. C. Bianco et al. Nature Reviews Endocrinology
- Isolated Familial Hypogonadotropic Hypogonadism and aGNRH1Mutation
- (2009) Jérôme Bouligand et al. NEW ENGLAND JOURNAL OF MEDICINE
- Recent Decline in Age at Breast Development: The Copenhagen Puberty Study
- (2009) L. Aksglaede et al. PEDIATRICS
- GNRH1mutations in patients with idiopathic hypogonadotropic hypogonadism
- (2009) Yee-Ming Chan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stage line diagram: An age-conditional reference diagram for tracking development
- (2009) Stef van Buuren et al. STATISTICS IN MEDICINE
- Is intracytoplasmic sperm injection essential for the treatment of hypogonadotrophic hypogonadism? A comparison between idiopathic and secondary hypogonadotrophic hypogonadism
- (2009) Berkan Resorlu et al. Human Fertility
- Mutations in CHD7, Encoding a Chromatin-Remodeling Protein, Cause Idiopathic Hypogonadotropic Hypogonadism and Kallmann Syndrome
- (2008) Hyung-Goo Kim et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Recombinant LH (lutropin alfa) for the treatment of hypogonadotrophic women with profound LH deficiency: a randomized, double-blind, placebo-controlled, proof-of-efficacy study
- (2008) Z. Shoham et al. CLINICAL ENDOCRINOLOGY
- Investigation, treatment and monitoring of late-onset hypogonadism in males
- (2008) C Wang et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Biallelic mutations in the prokineticin-2 gene in two sporadic cases of Kallmann syndrome
- (2008) Chrystel Leroy et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- A combined analysis of data to identify predictive factors for spermatogenesis in men with hypogonadotropic hypogonadism treated with recombinant human follicle-stimulating hormone and human chorionic gonadotropin
- (2008) David W. Warne et al. FERTILITY AND STERILITY
- Homozygous mutation in the prokineticin-receptor2 gene (Val274Asp) presenting as reversible Kallmann syndrome and persistent oligozoospermia: Case Report
- (2008) A. A. Sinisi et al. HUMAN REPRODUCTION
- Loss-of-Function Mutations in the Genes Encoding Prokineticin-2 or Prokineticin Receptor-2 Cause Autosomal Recessive Kallmann Syndrome
- (2008) Ana Paula Abreu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Physiological Androgen Insensitivity of the Fetal, Neonatal, and Early Infantile Testis Is Explained by the Ontogeny of the Androgen Receptor Expression in Sertoli Cells
- (2008) Héctor E. Chemes et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Mutations inProkineticin 2andProkineticin receptor 2genes in Human Gonadotrophin-Releasing Hormone Deficiency: Molecular Genetics and Clinical Spectrum
- (2008) Lindsay W. Cole et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Role of Gonadotropin-Releasing Hormone and Human Chorionic Gonadotropin Stimulation Tests in Differentiating Patients with Hypogonadotropic Hypogonadism from Those with Constitutional Delay of Growth and Puberty
- (2008) Terry Y. Segal et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Induction of Spermatogenesis and Fertility during Gonadotropin Treatment of Gonadotropin-Deficient Infertile Men: Predictors of Fertility Outcome
- (2008) Peter Y. Liu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice
- (2008) John Falardeau et al. JOURNAL OF CLINICAL INVESTIGATION
- TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction
- (2008) A Kemal Topaloglu et al. NATURE GENETICS
- Mutations in ligands and receptors of the leptin–melanocortin pathway that lead to obesity
- (2008) I Sadaf Farooqi et al. Nature clinical practice. Endocrinology & metabolism
- Patterns of Inheritance of Constitutional Delay of Growth and Puberty in Families of Adolescent Girls and Boys Referred to Specialist Pediatric Care
- (2007) Karoliina Wehkalampi et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now