Population genomics of invasive rodents on islands: Genetic consequences of colonization and prospects for localized synthetic gene drive

Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed gRNAs

(2020) Samuel E. Champer et al.   Science Advances

Performance analysis of novel toxin-antidote CRISPR gene drive systems

(2020) Jackson Champer et al.   BMC BIOLOGY

Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes

(2020) Hanno Schmidt et al.   Nature Communications

Super-Mendelian inheritance mediated by CRISPR–Cas9 in the female mouse germline

(2019) Hannah A. Grunwald et al.   NATURE

Population management using gene drive: molecular design, models of spread dynamics and assessment of ecological risks

(2019) Nicolas O. Rode et al.   CONSERVATION GENETICS

Tethered homing gene drives: a new design for spatially restricted population replacement and suppression

(2019) Sumit Dhole et al.   Evolutionary Applications

Rodent gene drives for conservation: opportunities and data needs

(2019) John Godwin et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Locally Fixed Alleles: A method to localize gene drive to island populations

(2019) Jaye Sudweeks et al.   Scientific Reports

Invasion and migration of spatially self-limiting gene drives: A comparative analysis

(2018) Sumit Dhole et al.   Evolutionary Applications

Reducing resistance allele formation in CRISPR gene drive

(2018) Jackson Champer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current CRISPR gene drive systems are likely to be highly invasive in wild populations

(2018) Charleston Noble et al.   eLife

Recent advances in threshold-dependent gene drives for mosquitoes

(2018) Philip T. Leftwich et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Measuring Genetic Differentiation from Pool-seq Data

(2018) Valentin Hivert et al.   GENETICS

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity

(2018) Johnny H. Hu et al.   NATURE

A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes

(2018) Kyros Kyrou et al.   NATURE BIOTECHNOLOGY

Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

(2018) Georg Oberhofer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse Genome Database (MGD) 2019

(2018) Carol J Bult et al.   NUCLEIC ACIDS RESEARCH

How to optimize the precision of allele and haplotype frequency estimates using pooled-sequencing data

(2017) Nicolas O. Rode et al.   Molecular Ecology Resources

Dodging silver bullets: good CRISPR gene-drive design is critical for eradicating exotic vertebrates

(2017) Thomas A. A. Prowse et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Is It Time for Synthetic Biodiversity Conservation?

(2017) Antoinette J. Piaggio et al.   TRENDS IN ECOLOGY & EVOLUTION

Profiling single-guide RNA specificity reveals a mismatch sensitive core sequence

(2017) Ting Zheng et al.   Scientific Reports

Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations

(2017) Jackson Champer et al.   PLoS Genetics

Evolution of Resistance Against CRISPR/Cas9 Gene Drive

(2016) Robert L. Unckless et al.   GENETICS

pcadapt: anRpackage to perform genome scans for selection based on principal component analysis

(2016) Keurcien Luu et al.   Molecular Ecology Resources

Invasive mammal eradication on islands results in substantial conservation gains

(2016) Holly P. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of Resistance Against CRISPR/Cas9 Gene Drive

(2016) Robert L. Unckless et al.   GENETICS

Genomic resources for wild populations of the house mouse, Mus musculus and its close relative Mus spretus

(2016) Bettina Harr et al.   Scientific Data

A Spontaneous Deletion within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype

(2015) Evgueni I. Kountikov et al.   AMERICAN JOURNAL OF PATHOLOGY

The next generation of rodent eradications: Innovative technologies and tools to improve species specificity and increase their feasibility on islands

(2015) Karl J. Campbell et al.   BIOLOGICAL CONSERVATION

Evaluation of variant detection software for pooled next-generation sequence data

(2015) Howard W. Huang et al.   BMC BIOINFORMATICS

Fast individual ancestry inference from DNA sequence data leveraging allele frequencies for multiple populations

(2015) Vikas Bansal et al.   BMC BIOINFORMATICS

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

(2015) Bernd Zetsche et al.   CELL

Genetics of Rapid and Extreme Size Evolution in Island Mice

(2015) M. M. Gray et al.   GENETICS

Safeguarding CRISPR-Cas9 gene drives in yeast

(2015) James E DiCarlo et al.   NATURE BIOTECHNOLOGY

A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae

(2015) Andrew Hammond et al.   NATURE BIOTECHNOLOGY

Sequencing pools of individuals — mining genome-wide polymorphism data without big funding

(2014) Christian Schlötterer et al.   NATURE REVIEWS GENETICS

First Steps towards Underdominant Genetic Transformation of Insect Populations

(2014) R. Guy Reeves et al.   PLoS One

Pool-hmm: a Python program for estimating the allele frequency spectrum and detecting selective sweeps from next generation sequencing of pooled samples

(2013) Simon Boitard et al.   Molecular Ecology Resources

DNA targeting specificity of RNA-guided Cas9 nucleases

(2013) Patrick D Hsu et al.   NATURE BIOTECHNOLOGY

Parallel Selection Mapping Using Artificially Selected Mice Reveals Body Weight Control Loci

(2012) Yingguang Frank Chan et al.   CURRENT BIOLOGY

Detecting Selective Sweeps from Pooled Next-Generation Sequencing Samples

(2012) S. Boitard et al.   MOLECULAR BIOLOGY AND EVOLUTION

Population genomics based on low coverage sequencing: how low should we go?

(2012) C. Alex Buerkle et al.   MOLECULAR ECOLOGY

LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets

(2012) Andreas Wilm et al.   NUCLEIC ACIDS RESEARCH

PoPoolation2: identifying differentiation between populations using sequencing of pooled DNA samples (Pool-Seq)

(2011) R. Kofler et al.   BIOINFORMATICS

The variant call format and VCFtools

(2011) P. Danecek et al.   BIOINFORMATICS

A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data

(2011) H. Li   BIOINFORMATICS

PoPoolation: A Toolbox for Population Genetic Analysis of Next Generation Sequencing Data from Pooled Individuals

(2011) Robert Kofler et al.   PLoS One

Of Mice and ‘Convicts’: Origin of the Australian House Mouse, Mus musculus

(2011) Sofia I. Gabriel et al.   PLoS One

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Evidence for Pervasive Adaptive Protein Evolution in Wild Mice

(2010) Daniel L. Halligan et al.   PLoS Genetics

Rodent-borne diseases and their risks for public health

(2009) Bastiaan G Meerburg et al.   CRITICAL REVIEWS IN MICROBIOLOGY

The House mice of the Faroe Islands: a study in microdifferentiation

(2009) R. J. Berry et al.   JOURNAL OF ZOOLOGY

Review of impacts of the introduced house mouse on islands in the Southern Ocean: are mice equivalent to rats?

(2008) Andrea Angel et al.   BIOLOGICAL INVASIONS

BROADENING THE APPLICATION OF EVOLUTIONARILY BASED GENETIC PEST MANAGEMENT

(2008) Fred Gould   EVOLUTION

The Population Genetics of Using Homing Endonuclease Genes in Vector and Pest Management

(2008) A. Deredec et al.   GENETICS