Dodging silver bullets: good CRISPR gene-drive design is critical for eradicating exotic vertebrates

Evolutionary dynamics of CRISPR gene drives

(2017) Charleston Noble et al.   Science Advances

Is there a future for genome-editing technologies in conservation?

(2016) J. A. Johnson et al.   ANIMAL CONSERVATION

Is There a Genetic Paradox of Biological Invasion?

(2016) Arnaud Estoup et al.   Annual Review of Ecology Evolution and Systematics

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes

(2016) Van Trung Chu et al.   BMC BIOTECHNOLOGY

Importance of lethal control of invasive predators for island conservation

(2016) James C. Russell et al.   CONSERVATION BIOLOGY

Gene editing can drive science to openness

(2016) Kevin Esvelt   NATURE

Augmenting CRISPR applications in Drosophila with tRNA-flanked sgRNAs

(2016) Fillip Port et al.   NATURE METHODS

Cheating evolution: engineering gene drives to manipulate the fate of wild populations

(2016) Jackson Champer et al.   NATURE REVIEWS GENETICS

Invasive predators and global biodiversity loss

(2016) Tim S. Doherty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of mosquito gene drive on malaria elimination in a computational model with explicit spatial and temporal dynamics

(2016) Philip A. Eckhoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two genes substitute for the mouse Y chromosome for spermatogenesis and reproduction

(2016) Y. Yamauchi et al.   SCIENCE

The Ecology and Evolutionary Dynamics of Meiotic Drive

(2016) Anna K. Lindholm et al.   TRENDS IN ECOLOGY & EVOLUTION

Genetic engineering to eradicate invasive mice on islands: modeling the efficiency and ecological impacts

(2016) Gregory A. Backus et al.   Ecosphere

An efficient protocol for the global sensitivity analysis of stochastic ecological models

(2016) Thomas A. A. Prowse et al.   Ecosphere

The next generation of rodent eradications: Innovative technologies and tools to improve species specificity and increase their feasibility on islands

(2015) Karl J. Campbell et al.   BIOLOGICAL CONSERVATION

Modeling the Manipulation of Natural Populations by the Mutagenic Chain Reaction

(2015) Robert L. Unckless et al.   GENETICS

Safeguarding CRISPR-Cas9 gene drives in yeast

(2015) James E DiCarlo et al.   NATURE BIOTECHNOLOGY

A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae

(2015) Andrew Hammond et al.   NATURE BIOTECHNOLOGY

Opinion: Is CRISPR-based gene drive a biocontrol silver bullet or global conservation threat?: Fig. 1.

(2015) Bruce L. Webber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system

(2015) Kabin Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquitoAnopheles stephensi

(2015) Valentino M. Gantz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mutagenic chain reaction: A method for converting heterozygous to homozygous mutations

(2015) V. M. Gantz et al.   SCIENCE

Safeguarding gene drive experiments in the laboratory

(2015) O. S. Akbari et al.   SCIENCE

Modeling the Manipulation of Natural Populations by the Mutagenic Chain Reaction

(2015) Robert L. Unckless et al.   GENETICS

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

(2014) Randall J. Platt et al.   CELL

An essential role for heat shock transcription factor binding protein 1 (HSBP1) during early embryonic development

(2014) Binnur Eroglu et al.   DEVELOPMENTAL BIOLOGY

A Mouse Geneticist's Practical Guide to CRISPR Applications

(2014) P. Singh et al.   GENETICS

Multiplexed and Programmable Regulation of Gene Networks with an Integrated RNA and CRISPR/Cas Toolkit in Human Cells

(2014) Lior Nissim et al.   MOLECULAR CELL

Development of synthetic selfish elements based on modular nucleases in Drosophila melanogaster

(2014) Alekos Simoni et al.   NUCLEIC ACIDS RESEARCH

Concerning RNA-guided gene drives for the alteration of wild populations

(2014) Kevin M Esvelt et al.   eLife

Combining the Trojan Y chromosome and daughterless carp eradication strategies

(2013) John L. Teem et al.   BIOLOGICAL INVASIONS

One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering

(2013) Hui Yang et al.   CELL

Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice

(2013) T. Mohun et al.   Disease Models & Mechanisms

Optimising Homing Endonuclease Gene Drive Performance in a Semi-Refractory Species: The Drosophila melanogaster Experience

(2013) Yuk-Sang Chan et al.   PLoS One

Two Y Genes Can Replace the Entire Y Chromosome for Assisted Reproduction in the Mouse

(2013) Yasuhiro Yamauchi et al.   SCIENCE

Of mice and men: Human RNA polymerase III promoter U6 is more efficient than its murine homologue for shRNA expression from a lentiviral vector in both human and murine progenitor cells

(2010) Roland Roelz et al.   EXPERIMENTAL HEMATOLOGY

Identification of SOX3 as an XX male sex reversal gene in mice and humans

(2010) Edwina Sutton et al.   JOURNAL OF CLINICAL INVESTIGATION

Review of negative effects of introduced rodents on small mammals on islands

(2008) Donna B. Harris   BIOLOGICAL INVASIONS

Gene-drive in age-structured insect populations

(2008) Yunxin Huang et al.   Evolutionary Applications

The Population Genetics of Using Homing Endonuclease Genes in Vector and Pest Management

(2008) A. Deredec et al.   GENETICS