Super-Mendelian inheritance mediated by CRISPR–Cas9 in the female mouse germline

Current CRISPR gene drive systems are likely to be highly invasive in wild populations

(2018) Charleston Noble et al.   eLife

A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes

(2018) Kyros Kyrou et al.   NATURE BIOTECHNOLOGY

CRISPR/Cas9 and active genetics-based trans-species replacement of the endogenous Drosophila kni-L2 CRM reveals unexpected complexity

(2017) Xiang-Ru Shannon Xu et al.   eLife

Evolutionary dynamics of CRISPR gene drives

(2017) Charleston Noble et al.   Science Advances

Overcoming evolved resistance to population-suppressing homing-based gene drives

(2017) John M. Marshall et al.   Scientific Reports

Evolution of Resistance Against CRISPR/Cas9 Gene Drive

(2016) Robert L. Unckless et al.   GENETICS

Evolution of Resistance Against CRISPR/Cas9 Gene Drive

(2016) Robert L. Unckless et al.   GENETICS

Systematic quantification of HDR and NHEJ reveals effects of locus, nuclease, and cell type on genome-editing

(2016) Yuichiro Miyaoka et al.   Scientific Reports

The dawn of active genetics

(2015) Valentino M. Gantz et al.   BIOESSAYS

Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing

(2015) Shin-Heng Chiou et al.   GENES & DEVELOPMENT

A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae

(2015) Andrew Hammond et al.   NATURE BIOTECHNOLOGY

Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquitoAnopheles stephensi

(2015) Valentino M. Gantz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mutagenic chain reaction: A method for converting heterozygous to homozygous mutations

(2015) V. M. Gantz et al.   SCIENCE

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

(2014) Randall J. Platt et al.   CELL

Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes

(2014) Shuo-Ting Yen et al.   DEVELOPMENTAL BIOLOGY

Concerning RNA-guided gene drives for the alteration of wild populations

(2014) Kevin M Esvelt et al.   eLife

Comparison of nonhomologous end joining and homologous recombination in human cells

(2008) Z MAO et al.   DNA REPAIR

BROADENING THE APPLICATION OF EVOLUTIONARILY BASED GENETIC PEST MANAGEMENT

(2008) Fred Gould   EVOLUTION

Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice

(2008) Patricia I. Sadate-Ngatchou et al.   GENESIS

The Population Genetics of Using Homing Endonuclease Genes in Vector and Pest Management

(2008) A. Deredec et al.   GENETICS