Current advancements and future perspectives of immunotherapy in colorectal cancer research

A review of cancer immunotherapy toxicity

(2020) Lucy Boyce Kennedy et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Colorectal cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

T cell receptors, mechanosensors, catch bonds and immunotherapy

(2020) Jia-huai Wang   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Expanding the Scope of Immunotherapy in Colorectal Cancer: Current Clinical Approaches and Future Directions

(2020) Malek Kreidieh et al.   Biomed Research International

T‐cell receptor affinity in the age of cancer immunotherapy

(2020) Michele M. Hoffmann et al.   MOLECULAR CARCINOGENESIS

Immunotherapy in Metastatic Colorectal Cancer: Could the Latest Developments Hold the Key to Improving Patient Survival?

(2020) Emmanouil Damilakis et al.   Cancers

Tumour-Associated Macrophages (TAMs) in Colon Cancer and How to Reeducate Them

(2019) M. A. F. Yahaya et al.   Journal of Immunology Research

Immunotherapy in colorectal cancer: rationale, challenges and potential

(2019) Karuna Ganesh et al.   Nature Reviews Gastroenterology & Hepatology

Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years

(2019) Fanny ER Vuik et al.   GUT

Bispecific antibodies: a mechanistic review of the pipeline

(2019) Aran F. Labrijn et al.   NATURE REVIEWS DRUG DISCOVERY

Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene

(2019) Hitoshi Hino et al.   Cancer Medicine

TCR–pMHC bond conformation controls TCR ligand discrimination

(2019) Dibyendu K. Sasmal et al.   Cellular & Molecular Immunology

Vitamin K3 (menadione) suppresses epithelial-mesenchymal-transition and Wnt signaling pathway in human colorectal cancer cells

(2019) Chandra Kishore et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The Two Faces of Tumor-Associated Macrophages and Their Clinical Significance in Colorectal Cancer

(2019) Marta L. Pinto et al.   Frontiers in Immunology

Immune checkpoint inhibitors for the treatment of MSI-H/MMR-D colorectal cancer and a perspective on resistance mechanisms

(2019) Ibrahim Halil Sahin et al.   BRITISH JOURNAL OF CANCER

Interpretation of somatic POLE mutations in endometrial carcinoma

(2019) Alicia León‐Castillo et al.   JOURNAL OF PATHOLOGY

Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair–Deficient/Microsatellite Instability–High Metastatic Colorectal Cancer

(2018) Michael J. Overman et al.   JOURNAL OF CLINICAL ONCOLOGY

Immobilizing Siderophores on Solid Surfaces for Bacterial Detection

(2018) Priyanka Bhadra et al.   JOURNAL OF THE ELECTROCHEMICAL SOCIETY

TCR Signaling: Mechanisms of Initiation and Propagation

(2018) Adam H. Courtney et al.   TRENDS IN BIOCHEMICAL SCIENCES

Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations

(2018) Judith A. Seidel et al.   Frontiers in Oncology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

PD-1/ PD-L1 blockade as a novel treatment for colorectal cancer

(2018) Neda Yaghoubi et al.   BIOMEDICINE & PHARMACOTHERAPY

Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study

(2017) Michael J Overman et al.   LANCET ONCOLOGY

Phase I Escalating-Dose Trial of CAR-T Therapy Targeting CEA + Metastatic Colorectal Cancers

(2017) Chengcheng Zhang et al.   MOLECULAR THERAPY

DNA Polymerase ɛ Deficiency Leading to an Ultramutator Phenotype: A Novel Clinically Relevant Entity

(2017) Enrico Castellucci et al.   ONCOLOGIST

PD-1 inhibitors in endometrial cancer

(2017) Romualdo Barroso-Sousa et al.   Oncotarget

Nivolumab as Programmed Death-1 (PD-1) Inhibitor for Targeted Immunotherapy in Tumor

(2017) Liting Guo et al.   Journal of Cancer

POLE somatic mutations in advanced colorectal cancer

(2017) Joana Guerra et al.   Cancer Medicine

CTLA-4 and PD-1 Pathways

(2016) Elizabeth I. Buchbinder et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

ESMO consensus guidelines for the management of patients with metastatic colorectal cancer

(2016) E. Van Cutsem et al.   ANNALS OF ONCOLOGY

Gut Microbiota, Inflammation, and Colorectal Cancer

(2016) Caitlin A. Brennan et al.   Annual Review of Microbiology

A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors

(2016) M. Bacac et al.   CLINICAL CANCER RESEARCH

Global patterns and trends in colorectal cancer incidence and mortality

(2016) Melina Arnold et al.   GUT

Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation

(2016) Ana C. Anderson et al.   IMMUNITY

Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer

(2016) Janice M. Mehnert et al.   JOURNAL OF CLINICAL INVESTIGATION

Selective transportation of charged ZnO nanoparticles and microorganism dialysis through silicon nanoporous membranes

(2016) Priyanka Bhadra et al.   JOURNAL OF MEMBRANE SCIENCE

Immunoscore encompassing CD3+ and CD8+ T cell densities in distant metastasis is a robust prognostic marker for advanced colorectal cancer

(2016) Yoonjin Kwak et al.   Oncotarget

A Nested Case–Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)

(2016) Neil Murphy et al.   PLOS MEDICINE

CEA TCB: A novel head-to-tail 2:1 T cell bispecific antibody for treatment of CEA-positive solid tumors

(2016) Marina Bacac et al.   OncoImmunology

Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma and Indolent B-Cell Malignancies Can Be Effectively Treated With Autologous T Cells Expressing an Anti-CD19 Chimeric Antigen Receptor

(2015) James N. Kochenderfer et al.   JOURNAL OF CLINICAL ONCOLOGY

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

(2015) Dung T. Le et al.   NEW ENGLAND JOURNAL OF MEDICINE

Confusing signals: Recent progress in CTLA-4 biology

(2015) Lucy S.K. Walker et al.   TRENDS IN IMMUNOLOGY

Studies on varying n-alkanethiol chain lengths on a gold coated surface and their effect on antibody–antigen binding efficiency

(2015) P. Bhadra et al.   RSC Advances

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

(2014) Shannon L. Maude et al.   NEW ENGLAND JOURNAL OF MEDICINE

Durable Cancer Regression Off-Treatment and Effective Reinduction Therapy with an Anti-PD-1 Antibody

(2012) E. J. Lipson et al.   CLINICAL CANCER RESEARCH

Sex disparities in colorectal cancer incidence by anatomic subsite, race and age

(2010) Gwen Murphy et al.   INTERNATIONAL JOURNAL OF CANCER

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

(2010) Julie R. Brahmer et al.   JOURNAL OF CLINICAL ONCOLOGY

T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis

(2010) Maria R Parkhurst et al.   MOLECULAR THERAPY