Influence of purinergic signaling on glucose transporters: A possible mechanism against insulin resistance?

Toxicity of Metformin and Hypoglycemic Therapies

(2020) Muhammad S. Akhter et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Alteration of purinergic signaling in diabetes: Focus on vascular function

(2020) Rui Zhou et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

P2X7 receptor mediates NLRP3 inflammasome activation in depression and diabetes

(2020) Danwen Wang et al.   Cell and Bioscience

Obesity Phenotypes, Diabetes, and Cardiovascular Diseases

(2020) Marie-Eve Piché et al.   CIRCULATION RESEARCH

P2Y2 Receptor Promotes High-Fat Diet-Induced Obesity

(2020) Yue Zhang et al.   Frontiers in Endocrinology

Metformin ameliorates experimental diabetic periodontitis independently of mammalian target of rapamycin (mTOR) inhibition by reducing NIMA‐related kinase 7(Nek7) expression

(2019) Xinyi Zhou et al.   JOURNAL OF PERIODONTOLOGY

Ion Channels of the Islets in Type 2 Diabetes

(2019) David Jacobson et al.   JOURNAL OF MOLECULAR BIOLOGY

P2X receptor-ion channels in the inflammatory response in adipose tissue and pancreas — potential triggers in onset of type 2 diabetes?

(2018) Ivana Novak et al.   CURRENT OPINION IN IMMUNOLOGY

Clinical pharmacokinetics, pharmacodynamics, safety, and tolerability of JNJ-54175446, a brain permeable P2X7 antagonist, in a randomised single-ascending dose study in healthy participants

(2018) Maarten Timmers et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Chemical biology probes of mammalian GLUT structure and function

(2018) Geoffrey D. Holman   BIOCHEMICAL JOURNAL

Inhibition of P2Y6 Signaling in AgRP Neurons Reduces Food Intake and Improves Systemic Insulin Sensitivity in Obesity

(2017) Sophie Marie Steculorum et al.   Cell Reports

P2X receptors

(2016) R. Alan North   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP

(2016) Mausita Karmakar et al.   Nature Communications

Modulation of Glucose Transporter Protein by Dietary Flavonoids in Type 2 Diabetes Mellitus

(2015) Fatemeh Hajiaghaalipour et al.   International Journal of Biological Sciences

Adenosine signalling in diabetes mellitus—pathophysiology and therapeutic considerations

(2015) Luca Antonioli et al.   Nature Reviews Endocrinology

Anticancer effect of adenosine on gastric cancerviadiverse signaling pathways

(2015) Ayako Tsuchiya   WORLD JOURNAL OF GASTROENTEROLOGY

Extracellular nucleotide and nucleoside signaling in vascular and blood disease

(2014) M. Idzko et al.   BLOOD

Enhancement of Glucose Uptake in Mouse Skeletal Muscle Cells and Adipocytes by P2Y6 Receptor Agonists

(2014) Ramachandran Balasubramanian et al.   PLoS One

A2B Adenosine Receptors Prevent Insulin Resistance by Inhibiting Adipose Tissue Inflammation via Maintaining Alternative Macrophage Activation

(2013) B. Csoka et al.   DIABETES

NLRP3 and IL-1βin macrophages as critical regulators of metabolic diseases

(2013) A. F. McGettrick et al.   DIABETES OBESITY & METABOLISM

ATP-P2X4 signaling mediates NLRP3 inflammasome activation: A novel pathway of diabetic nephropathy

(2013) Kehong Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Activation of inflammasomes in adipose tissue of women with gestational diabetes

(2013) Martha Lappas   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The SLC2 (GLUT) family of membrane transporters

(2013) Mike Mueckler et al.   MOLECULAR ASPECTS OF MEDICINE

Purinergic signalling and diabetes

(2013) Geoffrey Burnstock et al.   Purinergic Signalling

CD39 and CD73 in immunity and inflammation

(2013) Luca Antonioli et al.   TRENDS IN MOLECULAR MEDICINE

Deletion of CD73 promotes dyslipidemia and intramyocellular lipid accumulation in muscle of mice

(2013) Sandra Burghoff et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Clinical evaluation of the efficacy of the P2X7purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine

(2012) Edward C Keystone et al.   ANNALS OF THE RHEUMATIC DISEASES

Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects

(2012) Zahid Ali et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Glucose transporter 2 expression is down regulated following P2X7 activation in enterocytes

(2012) Jean-François Bourzac et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Efficacy and Safety of CE-224,535, an Antagonist of P2X7 Receptor, in Treatment of Patients with Rheumatoid Arthritis Inadequately Controlled by Methotrexate

(2012) T. C. STOCK et al.   JOURNAL OF RHEUMATOLOGY

Purinergic Signaling during Inflammation

(2012) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improved Insulin Sensitivity by GLUT12 Overexpression in Mice

(2011) S. H. Purcell et al.   DIABETES

GLUT12: a second insulin-responsive glucose transporters as an emerging target for type 2 diabetes

(2011) Takashi Matsuzaka et al.   Journal of Diabetes Investigation

Purinergic modulation of glucose uptake into cultured rat podocytes: Effect of diabetic milieu

(2010) Joanna Karczewska et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Facilitative glucose transporter 9, a unique hexose and urate transporter

(2009) Manuel Doblado et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucose transporters in the 21st Century

(2009) Bernard Thorens et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Novos mecanismos pelos quais o exercício físico melhora a resistência à insulina no músculo esquelético

(2009) José Rodrigo Pauli et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

ADP receptor P2Y13 induce apoptosis in pancreatic β-cells

(2009) Chanyuan Tan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins

(2009) Z. Wang et al.   JOURNAL OF CELL SCIENCE

GLUT7: a new intestinal facilitated hexose transporter

(2008) Chris Cheeseman   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Deletion of Cd39/Entpd1 Results in Hepatic Insulin Resistance

(2008) K. Enjyoji et al.   DIABETES

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

(2008) György Haskó et al.   NATURE REVIEWS DRUG DISCOVERY