Enhancing anti-melanoma outcomes in mice using novel chitooligosaccharide nanoparticles loaded with therapeutic survivin-targeted siRNA

Paclitaxel-Loaded Macrophage Membrane Camouflaged Albumin Nanoparticles for Targeted Cancer Therapy

(2020) Xi Cao et al.   International Journal of Nanomedicine

The current state and future directions of RNAi-based therapeutics

(2019) Ryan L. Setten et al.   NATURE REVIEWS DRUG DISCOVERY

Chitosan oligosaccharide (COS): An overview

(2019) Muhammad Naveed et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Co-Delivery of Eugenol and Dacarbazine by Hyaluronic Acid-Coated Liposomes for Targeted Inhibition of Survivin in Treatment of Resistant Metastatic Melanoma

(2019) Harshita Mishra et al.   Pharmaceutics

Natural Polysaccharides for siRNA Delivery: Nanocarriers Based on Chitosan, Hyaluronic Acid, and Their Derivatives

(2019) Inés Serrano-Sevilla et al.   MOLECULES

Polymeric Nanoparticles Based on Tyrosine-Modified, Low Molecular Weight Polyethylenimines for siRNA Delivery

(2019) Ewe et al.   Pharmaceutics

Survivin Monoclonal Antibodies Detect Survivin Cell Surface Expression and Inhibit Tumor GrowthIn Vivo

(2018) Robert A. Fenstermaker et al.   CLINICAL CANCER RESEARCH

Chitosan nanoparticles for the oral delivery of tenofovir disoproxil fumarate: formulation optimization, characterization and ex vivo and in vivo evaluation for uptake mechanism in rats

(2018) Joseph Shailender et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Synthesis, characterization, and in vitro cytotoxicity of fatty acyl-CGKRK-chitosan oligosaccharides conjugates for siRNA delivery

(2018) Naglaa Salem El-Sayed et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Functionalized nanoliposomes loaded with anti survivin and anti angiogenic agents to enhance the activity of chemotherapy against melanoma by 4-pronged action

(2018) Harshita Mishra et al.   MEDICAL HYPOTHESES

Quantum dots cause acute systemic toxicity in lactating rats and growth restriction of offspring

(2018) Lin Yang et al.   Nanoscale

Studies of acute and subchronic systemic toxicity associated with a copper/low-density polyethylene nanocomposite intrauterine device

(2018) Li-Xia Hu et al.   International Journal of Nanomedicine

The World of Melanoma: Epidemiologic, Genetic, and Anatomic Differences of Melanoma Across the Globe

(2018) Florentia Dimitriou et al.   Current Oncology Reports

Albumin-coated nanocrystals for carrier-free delivery of paclitaxel

(2017) Joonyoung Park et al.   JOURNAL OF CONTROLLED RELEASE

Activation of the CXCR4 chemokine receptor enhances biological functions associated with B16 melanoma liver metastasis

(2017) Mayela Mendt et al.   MELANOMA RESEARCH

Acute and subchronic toxicity studies of seabuckthorn ( Hippophae rhamnoides L.) oil in rodents

(2017) Peng Zhao et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Systemic siRNA Delivery with a Dual pH-Responsive and Tumor-targeted Nanovector for Inhibiting Tumor Growth and Spontaneous Metastasis in Orthotopic Murine Model of Breast Carcinoma

(2017) Bo Fan et al.   Theranostics

An effective tumor-targeting strategy utilizing hypoxia-sensitive siRNA delivery system for improved anti-tumor outcome

(2016) Lin Kang et al.   Acta Biomaterialia

Phenylboronic acid-sugar grafted polymer architecture as a dual stimuli-responsive gene carrier for targeted anti-angiogenic tumor therapy

(2016) Jinhwan Kim et al.   BIOMATERIALS

Clustering Small Dendrimers into Nanoaggregates for Efficient DNA and siRNA Delivery with Minimal Toxicity

(2016) Chongyi Liu et al.   Advanced Healthcare Materials

Survivin – The inconvenient IAP

(2015) Dario C. Altieri   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Downregulation of survivin expression exerts antitumoral effects on mouse breast cancer cells in vitro and in vivo

(2015) WEN-HUI MA et al.   Oncology Letters

The Molecular Pathology of Melanoma: An Integrated Taxonomy of Melanocytic Neoplasia

(2014) Boris C. Bastian   Annual Review of Pathology-Mechanisms of Disease

Small-sized polymeric micelles incorporating docetaxel suppress distant metastases in the clinically-relevant 4T1 mouse breast cancer model

(2014) Yunfei Li et al.   BMC CANCER

Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription

(2014) Jaime G Fernández et al.   Molecular Cancer

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

(2014) James E. Dahlman et al.   Nature Nanotechnology

Anti-tumor effects in mice induced by survivin-targeted siRNA delivered through polysaccharide nanoparticles

(2013) Feifei Yang et al.   BIOMATERIALS

Efficient siRNA delivery and tumor accumulation mediated by ionically cross-linked folic acid–poly(ethylene glycol)–chitosan oligosaccharide lactate nanoparticles: For the potential targeted ovarian cancer gene therapy

(2013) Tony Shing Chau Li et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Chitosan-based siRNA delivery systems

(2013) Héloïse Ragelle et al.   JOURNAL OF CONTROLLED RELEASE

Why is melanoma so metastatic?

(2013) Russell R. Braeuer et al.   Pigment Cell & Melanoma Research

Self-Assembled Vehicle Construction via Boronic Acid Coupling and Host-Guest Interaction for Serum-Tolerant DNA Transport and pH-Responsive Drug Delivery

(2013) Bin Yang et al.   Advanced Healthcare Materials

A Phenylboronate-Functionalized Polyion Complex Micelle for ATP-Triggered Release of siRNA

(2012) Mitsuru Naito et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

(2011) H. Cabral et al.   Nature Nanotechnology

Enhanced gene transfection capability of polyethylenimine by incorporating boronic acid groups

(2010) Qi Peng et al.   CHEMICAL COMMUNICATIONS

In vivo efficacy of paclitaxel-loaded injectable in situ-forming gel against subcutaneous tumor growth

(2010) Ju Young Lee et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS