Article
Food Science & Technology
Uyanga Batbold, Jun-Jen Liu
Summary: The combination of Seabuckthorn pulp oil (SBO) and Docetaxel (DTX) has demonstrated a synergistic anticancer effect against non-small cell lung cancer (NSCLC) cells. This effect is achieved through the induction of autophagy and senescence, increased ROS production, and inhibition of cancer cell growth. These findings provide important insights into new mechanisms for the treatment of lung cancer and highlight the potential of SBO as an alternative or adjunct therapy in combination with chemotherapy agents.
Article
Biochemistry & Molecular Biology
Chen-Xi Xia, Alex Xiong Gao, Yue Zhu, Tina Ting-Xia Dong, Karl Wah-Keung Tsim
Summary: Seabuckthorn, enriched with flavonoids, showed potential in treating major depressive disorder by improving depressive behaviors, regulating levels of neurotrophins, neurotransmitters, stress-related hormones, inflammation-related cytokines, and modulating gut microbiota.
Article
Physiology
Ming Li, Xuyang Zhao, Jiayuan Xie, Xinyu Tong, Junwei Shan, Mijuan Shi, Guangxin Wang, Weidong Ye, Yuhang Liu, Bruno Hamish Unger, Yingyin Cheng, Wanting Zhang, Nan Wu, Xiao-Qin Xia
Summary: The use of herbal medicine, such as seabuckthorn, in fish diets has shown potential for preventing and treating foodborne enteritis in aquaculture. A study using a zebrafish model demonstrated that seabuckthorn can reduce intestinal and hepatic inflammation and improve the immune response and gut microbiota composition.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Food Science & Technology
Shudan Tan, Yu Xu, Lichun Zhu, Zhihua Geng, Qian Zhang, Xuhai Yang
Summary: The combination of ultrasonic-assisted alkali and pricking holes is the most effective pretreatment method for improving the drying characteristics and quality attributes of seabuckthorn berries. The pretreatment of ultrasonic-assisted alkali helps dissolve the wax layer and form micropores, promoting water migration. All pretreatment methods reduce color difference.
Article
Plant Sciences
Chen-Xi Xia, Alex Xiong Gao, Tina Ting-Xia Dong, Karl Wah-Keung Tsim
Summary: The flavonoid-enriched fraction of seabuckthorn (SBF) was found to mimic neurotrophic functions by inducing neuronal cell differentiation through the activation of the PI3K/Akt and ERK pathways. SBF also showed synergistic effects with neurotrophic factors in promoting neurite outgrowth. The major flavonoids in SBF, including isorhamnetin, quercetin, and kaempferol, were identified as the active compounds responsible for the neurotrophic activities. These findings suggest the potential use of seabuckthorn as a health food supplement for treating brain disorders such as neurodegenerative diseases.
Article
Chemistry, Medicinal
Dattatraya Dinkar Gore, Furkan Ahmad, Kulbhushan Tikoo, Arvind Kumar Bansal, Dinesh Kumar, Inder Pal Singh
Summary: A combination of qNMR, GC-MS, and FTIR analysis methods can accurately determine the content of free fatty acids and triacylglycerols in seabuckthorn oil. Analysis of commercial samples revealed discrepancies between label claims and actual content.
CHINESE HERBAL MEDICINES
(2023)
Article
Plant Sciences
Yan Su, Shuxin Li, Hao Jiang, Baoli Duan, Meiyu Liu, Yuanbin Zhang
Summary: This study examined whether there are differences in the responses of female and male Chinese seabuckthorn (Hippophae rhamnoides subsp. sinensis Rousi) to elevated atmospheric carbon dioxide (CO2) and temperature. The results showed gender differences in biomass accumulation, photosynthetic capacity, nutrient absorption, and nonstructural carbohydrate contents. Elevated temperature inhibited the growth of females more than males, while elevated CO2 concentration promoted growth in both sexes, especially males.
ACTA PHYSIOLOGIAE PLANTARUM
(2023)
Article
Plant Sciences
Mengting Li, Xiaoyu Song, Jie Li, Xinxin Chen, Jianke Li, Chen Hou
Summary: The present study aimed to evaluate the toxic potential of lacquer seed oil (LSO). Results from acute toxicity study showed no mortality or toxic changes in rats treated with LSO. In the subchronic toxicity study, LSO did not induce significant toxicological changes in clinical observations, body weight, organ weight, biochemical or hematological parameters. Histopathological analysis revealed slight hepatic steatosis and inflammatory infiltration in rats treated with 5000 mg/kg/day of LSO, but this observation was not confirmed by hepatic biochemical analysis.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Biochemical Research Methods
Ankit Jain, Ashish Kumar, Prakash Chand Sharma
Summary: The study on genetic and morphometric diversity of seabuckthorn from different geographic sites revealed genetic variations among collections. The development of polymorphic microsatellite markers can serve as a reference for future seabuckthorn breeding and conservation strategies.
PLANT MOLECULAR BIOLOGY REPORTER
(2022)
Review
Plant Sciences
Swati Pundir, Prakrati Garg, Ananya Dviwedi, Aaliya Ali, V. K. Kapoor, Deepak Kapoor, Saurabh Kulshrestha, Uma Ranjan Lal, Poonam Negi
Summary: Sea buckthorn is a flowering shrub native to cold temperate regions of Eurasia, primarily found in China. It is widely used in folk medicine for various skin-related issues, with phytochemical studies revealing the presence of a wide variety of bioactive compounds. Pharmacological studies have demonstrated its antibacterial, anti-sebum, antifungal, anti-psoriasis, anti-atopic dermatitis and wound healing activities, making it a valuable ingredient in cosmeceuticals.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Parveen Akhter, Taseer Yasrab Bhatti, Iqrash Shafiq, Farrukh Jamil, Rabia Nazar, Muhammad Shahid Nazir, Sadaf Ul Hassan, Murid Hussain, YoungKwon Park
Summary: Sea buckthorn (SBT) is a nutritious plant that contains vital vitamins and various fatty acids. Its extracts are commonly used in cosmetics as an anti-aging ingredient and in pharmaceuticals for treating diseases. In this study, different organic solvents were used for oil extraction from sea buckthorn seeds, and the antioxidant activity was measured using the ferric reducing ability of plasma (FRAP) assay. The results showed that ethyl acetate extract had the highest FRAP, while isopropyl extract had the least FRAP.
KOREAN JOURNAL OF CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Applied
Xingang Lyu, Xiao Wang, Qilei Wang, Xueying Ma, Suolian Chen, Jianbo Xiao
Summary: Encapsulation of sea buckthorn leaf extracts using electrohydrodynamic technology protected polyphenols and flavonoids, enhancing their bioaccessibility in the intestine and preserving their antioxidant activity and inhibition of metabolic syndrome-related enzymes. This innovative method may promote the use of sea buckthorn as a nutritional supplement and expand its commercial applications.
Article
Medicine, Research & Experimental
Wen Yuan, Hongbo Wang, Yanling Gong
Summary: This study demonstrated that SSO significantly reduced kaolin intake and improved delayed gastric emptying caused by cisplatin-induced vomiting in rats. Furthermore, pretreatment with SSO significantly increased OXA concentration in both peripheral and central regions, as well as the expression of OX1R in the hypothalamus and brainstem.
IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
(2021)
Article
Food Science & Technology
Chuan-Guo Ma, Man Zhao, Tian-Lei Si, Xiao-Wei Chen
Summary: The study investigated the effects of different polysaccharide-adsorption treatments on the bioactive components and antioxidant activities of sea buckthorn pulp oil. The results showed that microwave-assisted activated clay adsorption was more effective in removing polysaccharides. Although the levels of bioactive components and antioxidant activities of SPO decreased during adsorption, the squalene content remained unchanged. Through principal component and correlation analyses, MAE-ACL was determined to be the more suitable polysaccharide-adsorption treatment.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Plant Sciences
Jerzy Zuchowski
Summary: Sea buckthorn, a thorny shrub or small tree, is rich in nutrients and has been extensively studied for its medicinal and cosmetic properties. Over the past decade, significant progress has been made in the research on sea buckthorn, including the discovery of new compounds and in-depth investigation of its pharmacological properties.
PHYTOCHEMISTRY REVIEWS
(2023)
Article
Environmental Sciences
Guangqiu Qin, Yunxia Xiong, Song Tang, Peng Zhao, Jon A. Doering, Shawn C. Beitel, Markus Hecker, Mao Wang, Hongling Liu, Haoliang Lu, Huamao Du
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2015)
Article
Environmental Sciences
Song Tang, Yonggan Wu, Caitlin N. Ryan, Shuangying Yu, Guangqiu Qin, Donn S. Edwards, Gregory D. Mayer
Article
Medicine, Legal
Guangqiu Qin, Pingjing Wen, Yanwu Wang, Lujuan Zhang, Huili Liang, Huiyan Qin, Song Tang, Peng Zhao
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2017)
Article
Environmental Sciences
Liu Jingchun, Yan Chongling, Zhang Ruifeng, Lu Haoliang, Qin Guangqiu
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2008)
Article
Environmental Sciences
Guangqiu Qin, Steven M. Presley, Todd A. Anderson, Weimin Gao, Jonathan D. Maul
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2011)
Article
Environmental Sciences
Morgan M. Willming, Guangqiu Qin, Jonathan D. Maul
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2013)
Article
Environmental Sciences
Darcy A. Chase, Donn S. Edwards, Guangqiu Qin, Mike R. Wages, Morgan M. Willming, Todd A. Anderson, Jonathan D. Maul
SCIENCE OF THE TOTAL ENVIRONMENT
(2013)
Article
Biotechnology & Applied Microbiology
Guangqiu Qin, Fang Wang, Huili Liang, Song Tang, Kamran Shekh, Yanwu Wang, Bin Li, Baiqing Dong, Pingjing Wen
BIOMED RESEARCH INTERNATIONAL
(2019)
Article
Biotechnology & Applied Microbiology
Huiyan Qin, Jiehong Zhang, Hui Yang, Siyu Yao, Li He, Huili Liang, Yanwu Wang, Huafeng Chen, Peng Zhao, Guangqiu Qin
BIOMED RESEARCH INTERNATIONAL
(2020)
Article
Medicine, Legal
Fiona Sewell, Ian Ragan, Graham Horgan, David Andrew, Thomas Holmes, Irene Manou, Boris P. Mueller, Tim Rowan, Barbara G. Schmitt, Marco Corvaro
Summary: There are currently three test guidelines for acute oral toxicity studies, but the subjectivity of one guideline may be hindering its wider use. In order to address this, the NC3Rs and EPAA collaborated to analyze historical data and provide recommendations on the recognition of 'evident toxicity'.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2024)
Article
Medicine, Legal
Michael DeVito, Bas Bokkers, Majorie B. M. van Duursen, Karin van Ede, Mark Feeley, Elsa Antunes Fernandes Gaspar, Laurie Haws, Sean Kennedy, Richard E. Peterson, Ron Hoogenboom, Keiko Nohara, Kim Petersen, Cynthia Rider, Martin Rose, Stephen Safe, Dieter Schrenk, Matthew W. Wheeler, Daniele S. Wikoff, Bin Zhao, Martin van den Berg
Summary: In October 2022, the World Health Organization reevaluated the toxic equivalency factors (TEFs) for chlorinated dioxin-like compounds in a panel convened in Lisbon. This effort utilized an updated database, Bayesian dose response modeling, and meta-analysis to derive Best-Estimate TEFs. Applying these new TEFs may result in lower total toxic equivalents for dioxin-like chemicals.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2024)