Recent achievements of bioluminescence imaging based on firefly luciferin-luciferase system

Recombinant expression of ecto-nucleotide pyrophosphatase/phosphodiesterase 4 (NPP4) and development of a luminescence-based assay to identify inhibitors

(2020) Vittoria Lopez et al.   ANALYTICAL BIOCHEMISTRY

Development of near‐infrared firefly luciferin analogue reacted with wild‐type and mutant luciferases

(2020) Nobuo Kitada et al.   CHIRALITY

A brief review of bioluminescent systems (2019)

(2019) Aubin Fleiss et al.   CURRENT GENETICS

Bioluminescent-based imaging and quantification of glucose uptake in vivo

(2019) Tamara Maric et al.   NATURE METHODS

Bioluminescence and near-infrared fluorescence imaging for detection of metastatic bone tumors

(2019) Wonbong Lim et al.   LASERS IN MEDICAL SCIENCE

Red-shifted bioluminescence Resonance Energy Transfer: Improved tools and materials for analytical in vivo approaches

(2019) Felix Weihs et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Building Biological Flashlights: Orthogonal Luciferases and Luciferins for in Vivo Imaging

(2019) Sierra J. Williams et al.   ACCOUNTS OF CHEMICAL RESEARCH

Efficient Strategy for the Synthesis and Modification of 2-Hydroxyethylluciferin for Highly Sensitive Bioluminescence Imaging of Endogenous Hydrogen Sulfide in Cancer Cells and Nude Mice

(2019) Xuewei Li et al.   ANALYTICAL CHEMISTRY

Recent progress in the synthesis of firefly luciferin derivatives

(2019) Radosław Podsiadły et al.   DYES AND PIGMENTS

In vivo bioluminescence imaging of labile iron pools in a murine model of sepsis with a highly selective probe

(2019) Ping Feng et al.   TALANTA

Caged luciferins for bioluminescent activity-based sensing

(2019) Timothy A Su et al.   CURRENT OPINION IN BIOTECHNOLOGY

Autonomous bioluminescence imaging of single mammalian cells with the bacterial bioluminescence system

(2019) Carola Gregor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lessons Learned from Luminous Luciferins and Latent Luciferases

(2018) Stephen C. Miller et al.   ACS Chemical Biology

A novel bioluminescence-based method to investigate uptake of bile acids in living cells

(2018) Alexander L Ticho et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

In Vivo Bioluminescence Imaging of Cobalt Accumulation in a Mouse Model

(2018) Bowen Ke et al.   ANALYTICAL CHEMISTRY

A Bioluminescent Probe for Imaging Endogenous Peroxynitrite in Living Cells and Mice

(2018) Jun-Bin Li et al.   ANALYTICAL CHEMISTRY

Pyridone Luciferins and Mutant Luciferases for Bioluminescence Imaging

(2018) Brendan S. Zhang et al.   CHEMBIOCHEM

An allylated firefly luciferin analogue with luciferase specific response in living cells

(2018) Yuma Ikeda et al.   CHEMICAL COMMUNICATIONS

Visualization of mercury(ii) accumulation in vivo using bioluminescence imaging with a highly selective probe

(2018) Bowen Ke et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Single-cell bioluminescence imaging of deep tissue in freely moving animals

(2018) Satoshi Iwano et al.   SCIENCE

Innovations in Instrumentation for Positron Emission Tomography

(2018) Eric Berg et al.   SEMINARS IN NUCLEAR MEDICINE

Quantum yield improvement of red-light-emitting firefly luciferin analogues for in vivo bioluminescence imaging

(2018) Masahiro Kiyama et al.   TETRAHEDRON

Toward bioluminescence in the near-infrared region: Tuning the emission wavelength of firefly luciferin analogues by allyl substitution

(2018) Nobuo Kitada et al.   TETRAHEDRON LETTERS

Click beetle luciferase mutant and near infrared naphthyl-luciferins for improved bioluminescence imaging

(2018) Mary P. Hall et al.   Nature Communications

Synthesis and luminescence properties of near-infrared N-heterocyclic luciferin analogues for in vivo optical imaging

(2018) Ryohei Saito et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Light emission miracle in the sea and preeminent applications of bioluminescence in recent new biotechnology

(2017) Sana Sharifian et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Orthogonal Luciferase–Luciferin Pairs for Bioluminescence Imaging

(2017) Krysten A. Jones et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rapid Access to a Broad Range of 6′-Substituted Firefly Luciferin Analogues Reveals Surprising Emitters and Inhibitors

(2017) Deepak K. Sharma et al.   ORGANIC LETTERS

In vivo bioluminescence imaging of labile iron accumulation in a murine model ofAcinetobacter baumanniiinfection

(2017) Allegra T. Aron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Molecular Bioluminescence Imaging: New Tools and Applications

(2017) Laura Mezzanotte et al.   TRENDS IN BIOTECHNOLOGY

Parallel Screening for Rapid Identification of Orthogonal Bioluminescent Tools

(2017) Colin M. Rathbun et al.   ACS Central Science

Real-Time Bioluminescence Imaging of Nitroreductase in Mouse Model

(2016) Ping Feng et al.   ANALYTICAL CHEMISTRY

Firefly Luciferase Mutants Allow Substrate-Selective Bioluminescence Imaging in the Mouse Brain

(2016) Spencer T. Adams et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Brominated Luciferins Are Versatile Bioluminescent Probes

(2016) Rachel C. Steinhardt et al.   CHEMBIOCHEM

1001 lights: luciferins, luciferases, their mechanisms of action and applications in chemical analysis, biology and medicine

(2016) Zinaida M. Kaskova et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of Firefly Luciferin Analogues and Evaluation of the Luminescent Properties

(2016) Shuji Ioka et al.   CHEMISTRY-A EUROPEAN JOURNAL

Design and Synthesis of an Alkynyl Luciferin Analogue for Bioluminescence Imaging

(2016) Rachel C. Steinhardt et al.   CHEMISTRY-A EUROPEAN JOURNAL

A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance

(2016) Cholsoon Jang et al.   NATURE MEDICINE

In vivo bioluminescence imaging reveals copper deficiency in a murine model of nonalcoholic fatty liver disease

(2016) Marie C. Heffern et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging

(2016) Takahiro Kuchimaru et al.   Nature Communications

CYP450 Enzymes Effect Oxygen-Dependent Reduction of Azide-Based Fluorogenic Dyes

(2016) Liam J. O’Connor et al.   ACS Central Science

Bioluminescence Probe for Detecting Hydrogen Sulfide in Vivo

(2015) Bowen Ke et al.   ANALYTICAL CHEMISTRY

Reaction-Based Turn-on Electrochemiluminescent Sensor with a Ruthenium(II) Complex for Selective Detection of Extracellular Hydrogen Sulfide in Rat Brain

(2015) Xiaoxiao Yue et al.   ANALYTICAL CHEMISTRY

Visualization of in Vivo Hydrogen Sulfide Production by a Bioluminescence Probe in Cancer Cells and Nude Mice

(2015) Xiaodong Tian et al.   ANALYTICAL CHEMISTRY

Development of a Sensitive Bioluminogenic Probe for Imaging Highly Reactive Oxygen Species in Living Rats

(2015) Ryosuke Kojima et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Luciferin Amides Enable in Vivo Bioluminescence Detection of Endogenous Fatty Acid Amide Hydrolase Activity

(2015) David M. Mofford et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of a Bioluminescent Nitroreductase Probe for Preclinical Imaging

(2015) Anzhelika G. Vorobyeva et al.   PLoS One

Bioluminescence-Activated Deep-Tissue Photodynamic Therapy of Cancer

(2015) Yi Rang Kim et al.   Theranostics

Discovery of Bioluminogenic Probes for Aminopeptidase N Imaging

(2014) Jing Li et al.   ANALYTICAL CHEMISTRY

Bioluminescent Probe for Hydrogen Peroxide Imaging in Vitro and in Vivo

(2014) Wenxiao Wu et al.   ANALYTICAL CHEMISTRY

A Dual-Color Far-Red to Near-Infrared Firefly Luciferin Analogue Designed for Multiparametric Bioluminescence Imaging

(2014) Amit P. Jathoul et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and bioluminescence of difluoroluciferin

(2014) Michael C. Pirrung et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Hypoxia in the intestine or solid tumors: A beneficial or deleterious alarm signal?

(2014) Hussein Shehade et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Aminoluciferins Extend Firefly Luciferase Bioluminescence into the Near-Infrared and Can Be Preferred Substrates over d-Luciferin

(2014) David M. Mofford et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A synthetic luciferin improves bioluminescence imaging in live mice

(2014) Melanie S Evans et al.   NATURE METHODS

The gut microbiota, bacterial metabolites and colorectal cancer

(2014) Petra Louis et al.   NATURE REVIEWS MICROBIOLOGY

Bioluminescence imaging: a shining future for cardiac regeneration

(2013) Santiago Roura et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Chemiluminescent Detection of Enzymatically Produced Hydrogen Sulfide: Substrate Hydrogen Bonding Influences Selectivity for H2S over Biological Thiols

(2013) T. Spencer Bailey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation

(2013) Genevieve C. Van de Bittner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visualizing cellular interactions with a generalized proximity reporter

(2013) M. A. Sellmyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of simple firefly luciferin analogs emitting blue, green, red, and near-infrared biological window light

(2013) Satoshi Iwano et al.   TETRAHEDRON

Synthesis and luminescence properties of biphenyl-type firefly luciferin analogs with a new, near-infrared light-emitting bioluminophore

(2013) Chihiro Miura et al.   TETRAHEDRON

Real-Time Noninvasive Imaging of Fatty Acid Uptake in Vivo

(2012) Amy H. Henkin et al.   ACS Chemical Biology

A bioluminescence assay for aldehyde dehydrogenase activity

(2012) Sarah J. Duellman et al.   ANALYTICAL BIOCHEMISTRY

Rational Design and Development of Near-Infrared-Emitting Firefly Luciferins Available In Vivo

(2012) Ryosuke Kojima et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Selenium Analogue of Firefly D-Luciferin with Red-Shifted Bioluminescence Emission

(2012) Nicholas R. Conley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vitro and In Vivo Uncaging and Bioluminescence Imaging by Using Photocaged Upconversion Nanoparticles

(2012) Yanmei Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioluminescence resonance energy transfer using luciferase-immobilized quantum dots for self-illuminated photodynamic therapy

(2012) Chia-Yen Hsu et al.   BIOMATERIALS

Development of 5′- and 7′-Substituted Luciferin Analogues as Acid-Tolerant Substrates of Firefly Luciferase

(2012) Hideo Takakura et al.   CHEMBIOCHEM

Cage the firefly luciferin! – a strategy for developing bioluminescent probes

(2012) Jing Li et al.   CHEMICAL SOCIETY REVIEWS

A  neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors

(2012) H. You et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Decade of Imaging Cellular Motility and Interaction Dynamics in the Immune System

(2012) R. N. Germain et al.   SCIENCE

Advances in the Understanding of Mammalian Copper Transporters

(2012) Yanfang Wang et al.   Advances in Nutrition

Highly reactive oxygen species: detection, formation, and possible functions

(2011) Wolfhardt Freinbichler et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Aminoluciferins as Functional Bioluminogenic Substrates of Firefly Luciferase

(2011) Hideo Takakura et al.   Chemistry-An Asian Journal

Computational Investigation of the Effect of pH on the Color of Firefly Bioluminescence by DFT

(2011) Luís Pinto da Silva et al.   CHEMPHYSCHEM

Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition

(2011) P. L. Meisenheimer et al.   DRUG METABOLISM AND DISPOSITION

ATP7A-related copper transport diseases—emerging concepts and future trends

(2011) Stephen G. Kaler   Nature Reviews Neurology

Molecular enigma of multicolor bioluminescence of firefly luciferase

(2010) Saman Hosseinkhani   CELLULAR AND MOLECULAR LIFE SCIENCES

Development of Luciferin Analogues Bearing an Amino Group and Their Application as BRET Donors

(2010) Hideo Takakura et al.   Chemistry-An Asian Journal

Robust Light Emission from Cyclic Alkylaminoluciferin Substrates for Firefly Luciferase

(2010) Gadarla Randheer Reddy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter

(2010) G. C. Van de Bittner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Bioluminescence Imaging of Furin Activity in Breast Cancer Cells Using Bioluminogenic Substrates

(2009) Anca Dragulescu-Andrasi et al.   BIOCONJUGATE CHEMISTRY

Copper, iron, and zinc ions homeostasis and their role in neurodegenerative disorders (metal uptake, transport, distribution and regulation)

(2009) Henryk Kozlowski et al.   COORDINATION CHEMISTRY REVIEWS

Guided by the light: visualizing biomolecular processes in living animals with bioluminescence

(2009) Jennifer A Prescher et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Structure and Spectroscopy of Oxyluciferin, the Light Emitter of the Firefly Bioluminescence

(2009) Panče Naumov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

(2008) G. Yang et al.   SCIENCE