Yeast translation elongation factor eEF3 promotes late stages of tRNA translocation

Molecular analysis of the ribosome recycling factor ABCE 1 bound to the 30S post‐splitting complex

(2020) Elina Nürenberg‐Goloub et al.   EMBO JOURNAL

RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1

(2020) Yoshitaka Matsuo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Ccr4-Not complex monitors the translating ribosome for codon optimality

(2020) Robert Buschauer et al.   SCIENCE

Collided ribosomes form a unique structural interface to induce Hel2‐driven quality control pathways

(2019) Ken Ikeuchi et al.   EMBO JOURNAL

Ribosome profiling analysis of eEF3-depleted Saccharomyces cerevisiae

(2019) Villu Kasari et al.   Scientific Reports

High-Resolution Ribosome Profiling Defines Discrete Ribosome Elongation States and Translational Regulation during Cellular Stress

(2019) Colin Chih-Chien Wu et al.   MOLECULAR CELL

Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance

(2018) Simone Pellegrino et al.   JOURNAL OF MOLECULAR BIOLOGY

Demonstration of translation elongation factor 3 activity from a non-fungal species, Phytophthora infestans

(2018) Maria K. Mateyak et al.   PLoS One

Translation in Prokaryotes

(2018) Marina V. Rodnina   Cold Spring Harbor Perspectives in Biology

Structural basis for antibiotic resistance mediated by theBacillus subtilisABCF ATPase VmlR

(2018) Caillan Crowe-McAuliffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1

(2018) Bertrand Beckert et al.   Nature Microbiology

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis

(2018) Julia Flis et al.   Cell Reports

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Thio-Modification of tRNA at the Wobble Position as Regulator of the Kinetics of Decoding and Translocation on the Ribosome

(2017) Namit Ranjan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

eIF5A Functions Globally in Translation Elongation and Termination

(2017) Anthony P. Schuller et al.   MOLECULAR CELL

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences

(2017) Vicent Pelechano et al.   NUCLEIC ACIDS RESEARCH

Three tRNAs on the ribosome slow translation elongation

(2017) Junhong Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation

(2016) Michael R Wasserman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Choreography of molecular movements during ribosome progression along mRNA

(2016) Riccardo Belardinelli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The cryo-EM structure of a ribosome–Ski2-Ski3-Ski8 helicase complex

(2016) Christian Schmidt et al.   SCIENCE

Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation

(2016) Michael R Wasserman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Choreography of molecular movements during ribosome progression along mRNA

(2016) Riccardo Belardinelli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Improved Ribosome-Footprint and mRNA Measurements Provide Insights into Dynamics and Regulation of Yeast Translation

(2016) David E. Weinberg et al.   Cell Reports

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

(2016) Dari Kimanius et al.   eLife

Structural Snapshots of Actively Translating Human Ribosomes

(2015) Elmar Behrmann et al.   CELL

Structural basis for the inhibition of the eukaryotic ribosome

(2014) Nicolas Garreau de Loubresse et al.   NATURE

How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation

(2014) J. Zhou et al.   SCIENCE

Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations

(2014) Egor Svidritskiy et al.   STRUCTURE

Mutations in the Chromodomain-like Insertion of Translation Elongation Factor 3 Compromise Protein Synthesis through Reduced ATPase Activity

(2013) Arjun N. Sasikumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An in vivo control map for the eukaryotic mRNA translation machinery

(2013) H. Firczuk et al.   Molecular Systems Biology

Heat Shock-Induced Accumulation of Translation Elongation and Termination Factors Precedes Assembly of Stress Granules in S. cerevisiae

(2013) Tomas Grousl et al.   PLoS One

Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis

(2013) L. Jenner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Differential proteomic analysis of Aspergillus fumigatus morphotypes reveals putative drug targets

(2012) Paula H. Kubitschek-Barreira et al.   Journal of Proteomics

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Possible steps of complete disassembly of post-termination complex by yeast eEF3 deduced from inhibition by translocation inhibitors

(2012) Shinya Kurata et al.   NUCLEIC ACIDS RESEARCH

The Elongation, Termination, and Recycling Phases of Translation in Eukaryotes

(2012) T. E. Dever et al.   Cold Spring Harbor Perspectives in Biology

Structure and Mechanisms of Lysine Methylation Recognition by the Chromodomain in Gene Transcription

(2011) Kyoko L. Yap et al.   BIOCHEMISTRY

Principles of mRNA transport in yeast

(2011) Roland Gerhard Heym et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Ribosomal L1 Protuberance in Yeast Is Methylated on a Lysine Residue Catalyzed by a Seven-β-strand Methyltransferase

(2011) Kristofor J. Webb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Dynamics of the Mammalian Ribosomal Pretranslocation Complex

(2011) Tatyana Budkevich et al.   MOLECULAR CELL

Saccharomyces Genome Database: the genomics resource of budding yeast

(2011) J. M. Cherry et al.   NUCLEIC ACIDS RESEARCH

Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1

(2011) D. Barthelme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stm1 modulates translation after 80S formation in Saccharomyces cerevisiae

(2011) V. Balagopal et al.   RNA

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Real-time tRNA transit on single translating ribosomes at codon resolution

(2010) Sotaro Uemura et al.   NATURE

Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

(2010) Niels Fischer et al.   NATURE

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

(2010) Tilman Schneider-Poetsch et al.   Nature Chemical Biology

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

Stm1p alters the ribosome association of eukaryotic elongation factor 3 and affects translation elongation

(2009) N. Van Dyke et al.   NUCLEIC ACIDS RESEARCH

Modulation of the Rate of Peptidyl Transfer on the Ribosome by the Nature of Substrates

(2008) Ingo Wohlgemuth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualization of the eEF2–80S Ribosome Transition-State Complex by Cryo-Electron Microscopy

(2008) Jayati Sengupta et al.   JOURNAL OF MOLECULAR BIOLOGY