Structural basis for the inhibition of the eukaryotic ribosome

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4′-O-substitutions determine selectivity of aminoglycoside antibiotics

(2014) Déborah Perez-Fernandez et al.   Nature Communications

Designer Aminoglycosides That Selectively Inhibit Cytoplasmic Rather than Mitochondrial Ribosomes Show Decreased Ototoxicity

(2013) Eli Shulman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The translation of translational control by FMRP: therapeutic targets for FXS

(2013) Jennifer C Darnell et al.   NATURE NEUROSCIENCE

Ribosome-targeting antibiotics and mechanisms of bacterial resistance

(2013) Daniel N. Wilson   NATURE REVIEWS MICROBIOLOGY

Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome

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Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State

(2013) S. Santagata et al.   SCIENCE

Aminoglycoside Antibiotics in the 21st Century

(2012) Bernd Becker et al.   ACS Chemical Biology

Elements of ribosomal drug resistance and specificity

(2012) Gregor M Blaha et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Crystal structure of the 80S yeast ribosome

(2012) Lasse Jenner et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A new understanding of the decoding principle on the ribosome

(2012) Natalia Demeshkina et al.   NATURE

One core, two shells: bacterial and eukaryotic ribosomes

(2012) Sergey Melnikov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution

(2012) S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sense from nonsense: therapies for premature stop codon diseases

(2012) Laure Bidou et al.   TRENDS IN MOLECULAR MEDICINE

Optimal fine ϕ-slicing for single-photon-counting pixel detectors

(2011) Marcus Mueller et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

(2011) Nicholas T. Ingolia et al.   CELL

Biosynthetic Studies and Genetic Engineering of Pactamycin Analogs with Improved Selectivity toward Malarial Parasites

(2011) Wanli Lu et al.   CHEMISTRY & BIOLOGY

Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6

(2011) S. Klinge et al.   SCIENCE

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

Genetic Reconstruction of Protozoan rRNA Decoding Sites Provides a Rationale for Paromomycin Activity against Leishmania and Trypanosoma

(2011) Sven N. Hobbie et al.   PLoS Neglected Tropical Diseases

Trichothecenes: From Simple to Complex Mycotoxins

(2011) Susan P. McCormick et al.   Toxins

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Methylation of Ribosomal Protein L42 Regulates Ribosomal Function and Stress-adapted Cell Growth

(2010) Atsuko Shirai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

(2010) Tilman Schneider-Poetsch et al.   Nature Chemical Biology

Structures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula marismortui

(2009) G. Gurel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:

(2009) Güliz Gürel et al.   JOURNAL OF MOLECULAR BIOLOGY

Biological Evaluation of Structurally Diverse Amaryllidaceae Alkaloids and their Synthetic Derivatives: Discovery of Novel Leads for Anticancer Drug Design

(2009) Antonio Evidente et al.   PLANTA MEDICA

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Design at the atomic level: Generation of novel hybrid biaryloxazolidinones as promising new antibiotics

(2008) Jiacheng Zhou et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS