N-methyl-d-aspartate receptor function in neuronal and synaptic development and signaling

Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial

(2020) Michael D Hill et al.   LANCET

Positive allosteric modulators that target NMDA receptors rectify loss-of-function GRIN variants associated with neurological and neuropsychiatric disorders

(2020) Weiting Tang et al.   NEUROPHARMACOLOGY

Functional assessment of triheteromeric NMDA receptors containing a human variant associated with epilepsy

(2019) Katie F. M. Marwick et al.   JOURNAL OF PHYSIOLOGY-LONDON

Heterogeneous clinical and functional features of GRIN2D-related developmental and epileptic encephalopathy

(2019) Wenshu XiangWei et al.   BRAIN

Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula

(2019) Y. Otsu et al.   SCIENCE

GRIN2D/GluN2D NMDA receptor: Unique features and its contribution to pediatric developmental and epileptic encephalopathy

(2019) Chad R. Camp et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Astroglial CB 1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory

(2018) Laurie M. Robin et al.   NEURON

Disease-associated missense mutations in GluN2B subunit alter NMDA receptor ligand binding and ion channel properties

(2018) Laura Fedele et al.   Nature Communications

The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms

(2018) Salvatore Incontro et al.   Nature Communications

Disruption of GRIN2B Impairs Differentiation in Human Neurons

(2018) Scott Bell et al.   Stem Cell Reports

Glutamate Activity Regulates and Dendritic Development of J-RGCs

(2018) Eerik Elias et al.   Frontiers in Cellular Neuroscience

GRIN2A-related disorders: genotype and functional consequence predict phenotype

(2018) Vincent Strehlow et al.   BRAIN

Direct Intracellular Signaling by the Carboxy terminus of NMDA Receptor GluN2 Subunits Regulates Dendritic Morphology in Hippocampal CA1 Pyramidal Neurons

(2018) Rachel E. Keith et al.   NEUROSCIENCE

Unmasking GluN1/GluN3A excitatory glycine NMDA receptors

(2018) Teddy Grand et al.   Nature Communications

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences

(2018) Sean McKay et al.   Cell Reports

Ecophysiology of the Olympia Oyster, Ostrea lurida, and Pacific Oyster, Crassostrea gigas

(2017) Matthew W. Gray et al.   Estuaries and Coasts

Functional Investigation of a GRIN2A Variant Associated with Rolandic Epilepsy

(2017) Xing-Xing Xu et al.   Neuroscience Bulletin

Long-term potentiation and the role of N -methyl- d -aspartate receptors

(2015) Arturas Volianskis et al.   BRAIN RESEARCH

Distinct roles of NMDA receptors at different stages of granule cell development in the adult brain

(2015) Yangling Mu et al.   eLife

Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith–Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity

(2014) David R. Adams et al.   MOLECULAR GENETICS AND METABOLISM

Encoding and Transducing the Synaptic or Extrasynaptic Origin of NMDA Receptor Signals to the Nucleus

(2013) Anna Karpova et al.   CELL

Functional properties of extrasynaptic AMPA and NMDA receptors during postnatal hippocampal neurogenesis

(2013) Charlotte Schmidt-Salzmann et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nuclear calcium signalling in the regulation of brain function

(2013) Hilmar Bading   NATURE REVIEWS NEUROSCIENCE

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

NMDA receptors and memory encoding

(2013) Richard G.M. Morris   NEUROPHARMACOLOGY

CaMKII binding to GluN2B is critical during memory consolidation

(2012) Amy R Halt et al.   EMBO JOURNAL

REST-dependent epigenetic remodeling promotes the developmental switch in synaptic NMDA receptors

(2012) Alma Rodenas-Ruano et al.   NATURE NEUROSCIENCE

Diagnostic Exome Sequencing in Persons with Severe Intellectual Disability

(2012) Joep de Ligt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic Deletion of NR3A Accelerates Glutamatergic Synapse Maturation

(2012) Maile A. Henson et al.   PLoS One

A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

(2012) A. Bach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GluN3 subunit-containing NMDA receptors: not just one-trick ponies

(2012) Svenja Pachernegg et al.   TRENDS IN NEUROSCIENCES

mGluR5 and NMDA Receptors Drive the Experience- and Activity-Dependent NMDA Receptor NR2B to NR2A Subunit Switch

(2011) Jose A. Matta et al.   NEURON

Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression

(2010) Marc-Andre Martel et al.   Channels

Deletions in 16p13 including GRIN2A in patients with intellectual disability, various dysmorphic features, and seizure disorders of the rolandic region

(2010) Constanze Reutlinger et al.   EPILEPSIA

Synaptic Activity and Nuclear Calcium Signaling Protect Hippocampal Neurons from Death Signal-associated Nuclear Translocation of FoxO3a Induced by ExtrasynapticN-Methyl-d-aspartate Receptors

(2010) Oliver Dick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Triheteromeric NR1/NR2A/NR2B Receptors Constitute the MajorN-Methyl-d-aspartate Receptor Population in Adult Hippocampal Synapses

(2010) Claudia Rauner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes

(2010) Sabine Endele et al.   NATURE GENETICS

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Downregulation of NR3A-Containing NMDARs Is Required for Synapse Maturation and Memory Consolidation

(2009) Adam C. Roberts et al.   NEURON

Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes

(2008) Tomás J Ryan et al.   BMC NEUROSCIENCE

Effectiveness of PSD95 Inhibitors in Permanent and Transient Focal Ischemia in the Rat

(2008) Hong-Shuo Sun et al.   STROKE