Recent insight into intermediate filament structure

Intermediate filaments in developing neurons: Beyond structure

(2020) Christopher J. Bott et al.   Cytoskeleton

The Interface between Keratin Structurotype and Human Disease

(2020) Sherif A. Eldirany et al.   STRUCTURE

Structure-Function Analyses of a Keratin Heterotypic Complex Identify Specific Keratin Regions Involved in Intermediate Filament Assembly

(2020) Chang-Hun Lee et al.   STRUCTURE

Liquid-liquid phase separation drives skin barrier formation

(2020) Felipe Garcia Quiroz et al.   SCIENCE

Addressing the Molecular Mechanism of Longitudinal Lamin Assembly Using Chimeric Fusions

(2020) Giel Stalmans et al.   Cells

Molecular Modeling of Pathogenic Mutations in the Keratin 1B Domain

(2020) Alexander J. Hinbest et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structural properties of target binding by profilaggrin A and B domains and other S100 fused-type calcium-binding proteins

(2020) Alexander J. Hinbest et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Non‐compaction cardiomyopathy is caused by a novel in‐frame desmin ( DES ) deletion mutation within the 1A coiled‐coil rod segment leading to a severe filament assembly defect

(2019) Andrey V Marakhonov et al.   HUMAN MUTATION

Human keratin 1/10‐1B tetramer structures reveal a knob‐pocket mechanism in intermediate filament assembly

(2019) Sherif A Eldirany et al.   EMBO JOURNAL

Intermediate Filaments as Effectors of Cancer Development and Metastasis: A Focus on Keratins, Vimentin, and Nestin

(2019) Pooja Sharma et al.   Cells

Structure of intermediate filament assembly in hair deduced from hydration studies using small-angle neutron scattering

(2019) N. Sanjeeva Murthy et al.   JOURNAL OF STRUCTURAL BIOLOGY

Helical twist direction in the macrofibrils of keratin fibres is left handed

(2019) Duane P. Harland et al.   JOURNAL OF STRUCTURAL BIOLOGY

An Emerin LEM-Domain Mutation Impairs Cell Response to Mechanical Stress

(2019) Nada Essawy et al.   Cells

Lateral A11 type tetramerization in lamins

(2019) Anastasia V. Lilina et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structural basis for lamin assembly at the molecular level

(2019) Jinsook Ahn et al.   Nature Communications

Assembly Kinetics of Vimentin Tetramers to Unit-Length Filaments: A Stopped-Flow Study

(2018) Norbert Mücke et al.   BIOPHYSICAL JOURNAL

An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin in cancer cells

(2018) Kathryn P. Trogden et al.   FASEB JOURNAL

A crystal structure of coil 1B of vimentin in the filamentous form provides a model of a high-order assembly of a vimentin filament

(2018) Allan H. Pang et al.   FEBS Journal

Mammalian Plakins, Giant Cytolinkers: Versatile Biological Functions and Roles in Cancer

(2018) Lifang Hu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks

(2018) Michael P. Hughes et al.   SCIENCE

Cytoplasmic Intermediate Filaments in Cell Biology

(2018) Sandrine Etienne-Manneville   Annual Review of Cell and Developmental Biology

Crystal structure of the human glial fibrillary acidic protein 1B domain

(2018) Bitnarae Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases

(2018) Camille Samson et al.   NUCLEIC ACIDS RESEARCH

Skeletal Muscle Dystrophy mutant of lamin A alters the structure and dynamics of the Ig fold domain

(2018) Subarna Dutta et al.   Scientific Reports

Vimentin Diversity in Health and Disease

(2018) Frida Danielsson et al.   Cells

The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease

(2017) Christopher G. Bunick et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Modeling the Structure of Keratin 1 and 10 Terminal Domains and their Misassembly in Keratoderma

(2017) Cedric Badowski et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The molecular architecture of lamins in somatic cells

(2017) Yagmur Turgay et al.   NATURE

A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers

(2017) Michael J. Bollong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurofilaments and Neurofilament Proteins in Health and Disease

(2017) Aidong Yuan et al.   Cold Spring Harbor Perspectives in Biology

Intermediate Filaments: Structure and Assembly

(2016) Harald Herrmann et al.   Cold Spring Harbor Perspectives in Biology

Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin

(2016) Claudia Fogl et al.   Nature Communications

Keratins in health and disease

(2015) Diana M Toivola et al.   CURRENT OPINION IN CELL BIOLOGY

Vimentin intermediate filament and plectin provide a scaffold for invadopodia, facilitating cancer cell invasion and extravasation for metastasis

(2014) Mihoko Sutoh Yoneyama et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Tubulin Inhibitors: A Patent Survey

(2014) Kunal Nepali et al.   Recent Patents on Anti-Cancer Drug Discovery

Hinged Plakin Domains Provide Specialized Degrees of Articulation in Envoplakin, Periplakin and Desmoplakin

(2013) Caezar Al-Jassar et al.   PLoS One

Emerin in health and disease

(2013) Adam J. Koch et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The nuclear envelope LEM-domain protein emerin

(2013) Jason M Berk et al.   Nucleus

The Structure of Vimentin Linker 1 and Rod 1B Domains Characterized by Site-directed Spin-labeling Electron Paramagnetic Resonance (SDSL-EPR) and X-ray Crystallography

(2012) Atya Aziz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for heteromeric assembly and perinuclear organization of keratin filaments

(2012) Chang-Hun Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Withaferin A Alters Intermediate Filament Organization, Cell Shape and Behavior

(2012) Boris Grin et al.   PLoS One

Vimentin in cancer and its potential as a molecular target for cancer therapy

(2011) Arun Satelli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

One Remarkable Molecule: Filaggrin

(2011) Sara J. Brown et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia

(2010) Marie Schoumacher et al.   JOURNAL OF CELL BIOLOGY

Atomic structure of vimentin coil 2

(2010) Stefan Nicolet et al.   JOURNAL OF STRUCTURAL BIOLOGY

Keratins in health and cancer: more than mere epithelial cell markers

(2010) V Karantza   ONCOGENE

Filaggrin in the frontline: role in skin barrier function and disease

(2009) A. Sandilands et al.   JOURNAL OF CELL SCIENCE

“IF-pathies”: a broad spectrum of intermediate filament–associated diseases

(2009) M. Bishr Omary   JOURNAL OF CLINICAL INVESTIGATION

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS