Virtual patients for mechanical ventilation in the intensive care unit

The ‘Digital Twin’ to enable the vision of precision cardiology

(2020) Jorge Corral-Acero et al.   EUROPEAN HEART JOURNAL

Model-based PEEP titration versus standard practice in mechanical ventilation: a randomised controlled trial

(2020) Kyeong Tae Kim et al.   Trials

Lung Recruitability in COVID-19–associated Acute Respiratory Distress Syndrome: A Single-Center Observational Study

(2020) Chun Pan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Parameter updating of a patient-specific lung mechanics model for optimising mechanical ventilation

(2020) Qianhui Sun et al.   Biomedical Signal Processing and Control

Prediction of lung mechanics throughout recruitment maneuvers in pressure-controlled ventilation

(2020) Sophie E. Morton et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Support vector machines for automated modelling of nonlinear structures using health monitoring results

(2020) Cong Zhou et al.   MECHANICAL SYSTEMS AND SIGNAL PROCESSING

Degradation evaluation of lateral story stiffness using HLA-based deep learning networks

(2019) Cong Zhou et al.   ADVANCED ENGINEERING INFORMATICS

Predictive Virtual Patient Modelling of Mechanical Ventilation: Impact of Recruitment Function

(2019) Sophie E. Morton et al.   ANNALS OF BIOMEDICAL ENGINEERING

Optimising mechanical ventilation through model-based methods and automation

(2019) Sophie E. Morton et al.   ANNUAL REVIEWS IN CONTROL

Using Injury Cost Functions from a Predictive Single Compartment Model to Assess the Severity of Mechanical Ventilator Induced Lung Injuries

(2019) Michelle M. Mellenthin et al.   JOURNAL OF APPLIED PHYSIOLOGY

Next-generation, personalised, model-based critical care medicine: a state-of-the art review of in silico virtual patient models, methods, and cohorts, and how to validation them

(2018) J. Geoffrey Chase et al.   Biomedical Engineering Online

A virtual patient model for mechanical ventilation

(2018) S.E. Morton et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Biomedical engineer’s guide to the clinical aspects of intensive care mechanical ventilation

(2018) Vincent J. Major et al.   Biomedical Engineering Online

Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome

(2017) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Extrapolation of a non-linear autoregressive model of pulmonary mechanics

(2017) Ruby Langdon et al.   MATHEMATICAL BIOSCIENCES

Comparing model-based adaptive LMS filters and a model-free hysteresis loop analysis method for structural health monitoring

(2017) Cong Zhou et al.   MECHANICAL SYSTEMS AND SIGNAL PROCESSING

Predicting ventilator-induced lung injury using a lung injury cost function

(2016) Katharine L. Hamlington et al.   JOURNAL OF APPLIED PHYSIOLOGY

Physical Parameter Identification of Structural Systems with Hysteretic Pinching

(2015) Cong Zhou et al.   COMPUTER-AIDED CIVIL AND INFRASTRUCTURE ENGINEERING

Lung Recruitability Is Better Estimated According to the Berlin Definition of Acute Respiratory Distress Syndrome at Standard 5 cm H2O Rather Than Higher Positive End-Expiratory Pressure

(2015) Pietro Caironi et al.   CRITICAL CARE MEDICINE

Driving Pressure and Survival in the Acute Respiratory Distress Syndrome

(2015) Marcelo B.P. Amato et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recruitment Maneuvers and PEEP Titration

(2015) D. R. Hess   Respiratory Care

Overall damage identification of flag-shaped hysteresis systems under seismic excitation

(2015) Cong Zhou et al.   Smart Structures and Systems

The Clinical Utilisation of Respiratory Elastance Software (CURE Soft): a bedside software for real-time respiratory mechanics monitoring and mechanical ventilation management

(2014) Akos Szlavecz et al.   Biomedical Engineering Online

Reformulation of the pressure-dependent recruitment model (PRM) of respiratory mechanics

(2014) Paul D. Docherty et al.   Biomedical Signal Processing and Control

Utility of a novel error-stepping method to improve gradient-based parameter identification by increasing the smoothness of the local objective surface: A case-study of pulmonary mechanics

(2013) Paul D. Docherty et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Lung Stress and Strain During Mechanical Ventilation

(2013) Alessandro Protti et al.   CRITICAL CARE MEDICINE

Multi-scale computational models of the airways to unravel the pathophysiological mechanisms in asthma and chronic obstructive pulmonary disease (AirPROM)

(2013) K. S. Burrowes et al.   Interface Focus

Structural Identifiability and Practical Applicability of an Alveolar Recruitment Model for ARDS Patients

(2012) Christoph Schranz et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Continuum vs. spring network models of airway-parenchymal interdependence

(2012) Baoshun Ma et al.   JOURNAL OF APPLIED PHYSIOLOGY

A Multi-Scale Approach to Airway Hyperresponsiveness: From Molecule to Organ

(2012) Anne-Marie Lauzon et al.   Frontiers in Physiology

Lung Regional Metabolic Activity and Gas Volume Changes Induced by Tidal Ventilation in Patients with Acute Lung Injury

(2011) Giacomo Bellani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A graphical method for practical and informative identifiability analyses of physiological models: A case study of insulin kinetics and sensitivity

(2011) Paul D Docherty et al.   Biomedical Engineering Online

Positive end expiratory pressure in patients with acute respiratory distress syndrome – The past, present and future

(2011) Ashwath Sundaresan et al.   Biomedical Signal Processing and Control

Multi-scale lung modeling

(2011) Merryn H. Tawhai et al.   JOURNAL OF APPLIED PHYSIOLOGY

Modeling the Complex Dynamics of Derecruitment in the Lung

(2010) Baoshun Ma et al.   ANNALS OF BIOMEDICAL ENGINEERING

A model of ventilation of the healthy human lung

(2010) K.L. Steimle et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Lung recruitability in ARDS H1N1 patients

(2010) D. Chiumello et al.   INTENSIVE CARE MEDICINE

Higher vs Lower Positive End-Expiratory Pressure in Patients With Acute Lung Injury and Acute Respiratory Distress Syndrome

(2010) Matthias Briel et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Hysteresis Bouc-Wen Model, a Survey

(2009) Mohammed Ismail et al.   ARCHIVES OF COMPUTATIONAL METHODS IN ENGINEERING

Bedside estimation of recruitable alveolar collapse and hyperdistension by electrical impedance tomography

(2009) Eduardo L. V. Costa et al.   INTENSIVE CARE MEDICINE

Towards a virtual lung: multi-scale, multi-physics modelling of the pulmonary system

(2008) K.S Burrowes et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES