Multi-scale computational models of the airways to unravel the pathophysiological mechanisms in asthma and chronic obstructive pulmonary disease (AirPROM)

Update in Chronic Obstructive Pulmonary Disease 2011

(2012) Alvar Agustí et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The EvA study: aims and strategy

(2012) Loems Ziegler-Heitbrock et al.   EUROPEAN RESPIRATORY JOURNAL

Assessing potential errors of MRI-based measurements of pulmonary blood flow using a detailed network flow model

(2012) K. S. Burrowes et al.   JOURNAL OF APPLIED PHYSIOLOGY

A computational model of the topographic distribution of ventilation in healthy human lungs

(2012) Annalisa J. Swan et al.   JOURNAL OF THEORETICAL BIOLOGY

Chronic obstructive pulmonary disease

(2012) Marc Decramer et al.   LANCET

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

(2012) Ian D Pavord et al.   LANCET

Relationship between quantitative CT metrics and health status and BODE in chronic obstructive pulmonary disease

(2012) Carlos H Martinez et al.   THORAX

Trials and tribulations in identifying new biologic treatments for asthma

(2012) Stephen T. Holgate   TRENDS IN IMMUNOLOGY

An infrastructure for ontology-based information systems in biomedicine: RICORDO case study

(2011) S. M. Wimalaratne et al.   BIOINFORMATICS

Lung damage and airway remodelling in severe asthma

(2011) C. E. Brightling et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The acute effect of budesonide/formoterol in COPD: a multi-slice computed tomography and lung function study

(2011) Lieve A. De Backer et al.   EUROPEAN RESPIRATORY JOURNAL

Modelling complex biological systems using an agent-based approach

(2011) Mike Holcombe et al.   Integrative Biology

The interdependent contributions of gravitational and structural features to perfusion distribution in a multiscale model of the pulmonary circulation

(2011) A. R. Clark et al.   JOURNAL OF APPLIED PHYSIOLOGY

Multi-scale lung modeling

(2011) Merryn H. Tawhai et al.   JOURNAL OF APPLIED PHYSIOLOGY

Retrieval, alignment, and clustering of computational models based on semantic annotations

(2011) M. Schulz et al.   Molecular Systems Biology

Multiscale mathematical models of airway constriction and disease

(2011) Graham M. Donovan   PULMONARY PHARMACOLOGY & THERAPEUTICS

Towards individualised treatment in COPD

(2011) J. Fingleton et al.   THORAX

Modeling the dynamics of airway constriction: effects of agonist transport and binding

(2010) Samir D. Amin et al.   JOURNAL OF APPLIED PHYSIOLOGY

Experimental investigation and numerical simulation of 3He gas diffusion in simple geometries: Implications for analytical models of 3He MR lung morphometry

(2010) J. Parra-Robles et al.   JOURNAL OF MAGNETIC RESONANCE

Development of a Three Dimensional Multiscale Computational Model of the Human Epidermis

(2010) Salem Adra et al.   PLoS One

Validation of Computational Fluid Dynamics in CT-based Airway Models with SPECT/CT

(2010) Jan W. De Backer et al.   RADIOLOGY

Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI)

(2010) E. H. Bel et al.   THORAX

Refractory asthma in the UK: cross-sectional findings from a UK multicentre registry

(2010) L. G. Heaney et al.   THORAX

Effectiveness and Safety of Bronchial Thermoplasty in the Treatment of Severe Asthma

(2009) Mario Castro et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Biological knowledge management: the emerging role of the Semantic Web technologies

(2009) E. Antezana et al.   BRIEFINGS IN BIOINFORMATICS

Supine and prone differences in regional lung density and pleural pressure gradients in the human lung with constant shape

(2009) Merryn H. Tawhai et al.   JOURNAL OF APPLIED PHYSIOLOGY

Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

A biomechanical model of agonist-initiated contraction in the asthmatic airway

(2009) B.S. Brook et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Cluster Analysis and Clinical Asthma Phenotypes

(2008) Pranab Haldar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Computational fluid dynamics can detect changes in airway resistance in asthmatics after acute bronchodilation

(2007) J.W. De Backer et al.   JOURNAL OF BIOMECHANICS

Flow analyses in the lower airways: Patient-specific model and boundary conditions

(2007) J.W. De Backer et al.   MEDICAL ENGINEERING & PHYSICS