Virus vaccines: proteins prefer prolines

Immunogenicity of clinically relevant SARS-CoV-2 vaccines in non-human primates and humans

(2021) P. J. Klasse et al.   Science Advances

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Rapid COVID-19 vaccine development

(2020) Barney S. Graham   SCIENCE

DNA vaccine protection against SARS-CoV-2 in rhesus macaques

(2020) Jingyou Yu et al.   SCIENCE

Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers

(2020) Lucy Rutten et al.   Cell Reports

SARS-CoV-2 vaccines: ‘Warp Speed’ needs mind melds not warped minds

(2020) John P. Moore et al.   JOURNAL OF VIROLOGY

Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

(2020) Noe B. Mercado et al.   NATURE

Structure-based design of prefusion-stabilized SARS-CoV-2 spikes

(2020) Ching-Lin Hsieh et al.   SCIENCE

SARS-CoV-2 vaccines in development

(2020) Florian Krammer   NATURE

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

(2020) Rinke Bos et al.   npj Vaccines

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

(2020) Merryn Voysey et al.   LANCET

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

(2020) Fernando P. Polack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antibody responses to viral infections: a structural perspective across three different enveloped viruses

(2019) Charles D. Murin et al.   Nature Microbiology

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

(2019) Alexandra C. Walls et al.   CELL

Structure-Based Vaccine Antigen Design

(2019) Barney S. Graham et al.   Annual Review of Medicine

Summary of the Vaccines and Related Biological Products Advisory Committee meeting held to consider evaluation of vaccine candidates for the prevention of respiratory syncytial virus disease in RSV-naïve infants

(2019) Sarah K. Browne et al.   VACCINE

Stabilizing HIV-1 envelope glycoprotein trimers to induce neutralizing antibodies

(2018) Alba Torrents de la Peña et al.   Retrovirology

The HIV-1 envelope glycoprotein structure: nailing down a moving target

(2017) Andrew B Ward et al.   IMMUNOLOGICAL REVIEWS

Native-like Env trimers as a platform for HIV-1 vaccine design

(2017) Rogier W. Sanders et al.   IMMUNOLOGICAL REVIEWS

An Adjuvanted, Postfusion F Protein–Based Vaccine Did Not Prevent Respiratory Syncytial Virus Illness in Older Adults

(2017) Judith Falloon et al.   JOURNAL OF INFECTIOUS DISEASES

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

(2017) Jesper Pallesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for antibody-mediated neutralization of Lassa virus

(2017) Kathryn M. Hastie et al.   SCIENCE

Structure and immunogenicity of pre-fusion-stabilized human metapneumovirus F glycoprotein

(2017) Michael B. Battles et al.   Nature Communications

Vaccine development for respiratory syncytial virus

(2017) Barney S Graham   Current Opinion in Virology

Vaccines against respiratory syncytial virus: The time has finally come

(2016) Barney S. Graham   VACCINE

HIV-1 neutralizing antibodies induced by native-like envelope trimers

(2015) R. W. Sanders et al.   SCIENCE

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

(2015) Anders Krarup et al.   Nature Communications

Mechanisms of Virus Membrane Fusion Proteins

(2014) Margaret Kielian   Annual Review of Virology

Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

(2013) R. P. Ringe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

(2013) J. S. McLellan et al.   SCIENCE

A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies

(2013) Rogier W. Sanders et al.   PLoS Pathogens