Reduced RBX1 expression induces chromosome instability and promotes cellular transformation in high-grade serous ovarian cancer precursor cells
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Title
Reduced RBX1 expression induces chromosome instability and promotes cellular transformation in high-grade serous ovarian cancer precursor cells
Authors
Keywords
Chromosome instability, High-grade serous ovarian cancer, RBX1, SCF Complex, Quantitative imaging microscopy
Journal
CANCER LETTERS
Volume 500, Issue -, Pages 194-207
Publisher
Elsevier BV
Online
2020-12-05
DOI
10.1016/j.canlet.2020.11.051
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Note: Only part of the references are listed.- Reduced Expression of Genes Regulating Cohesion Induces Chromosome Instability that May Promote Cancer and Impact Patient Outcomes
- (2020) Tarik R. Leylek et al. Scientific Reports
- Reduced SKP1 Expression Induces Chromosome Instability through Aberrant Cyclin E1 Protein Turnover
- (2020) Laura L. Thompson et al. Cancers
- Chromosome Instability; Implications in Cancer Development, Progression, and Clinical Outcomes
- (2020) Raghvendra Vishwakarma et al. Cancers
- Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice
- (2019) Khaled Aziz et al. GASTROENTEROLOGY
- Quality and quantity control of gene expression by nonsense-mediated mRNA decay
- (2019) Tatsuaki Kurosaki et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Micronuclei and Genome Chaos: Changing the System Inheritance
- (2019) Christine J. Ye et al. Genes
- Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer
- (2018) Katherine A. Hoadley et al. CELL
- Nonsense-mediated mRNA Decay and Cancer
- (2018) Maximilian W Popp et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Endoreplication: The Good, the Bad, and the Ugly
- (2018) Zhiqiang Shu et al. TRENDS IN CELL BIOLOGY
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- 19q12 amplified and non-amplified subsets of high grade serous ovarian cancer with overexpression of cyclin E1 differ in their molecular drivers and clinical outcomes
- (2018) Diar Aziz et al. GYNECOLOGIC ONCOLOGY
- KIF11 silencing and inhibition induces chromosome instability that may contribute to cancer
- (2017) Yasamin Asbaghi et al. GENES CHROMOSOMES & CANCER
- The enigmatic oncogene and tumor suppressor-like properties of RAD54B: Insights into genome instability and cancer
- (2017) Erin N. McAndrew et al. GENES CHROMOSOMES & CANCER
- High grade serous ovarian carcinomas originate in the fallopian tube
- (2017) S. Intidhar Labidi-Galy et al. Nature Communications
- Reconstitution of high-grade serous ovarian carcinoma from primary fallopian tube secretory epithelial cells
- (2017) Kohei Nakamura et al. Oncotarget
- Targeting the overexpressed ROC1 induces G2 cell cycle arrest and apoptosis in esophageal cancer cells
- (2017) Jingyang Zhang et al. Oncotarget
- The temporal dynamics of chromosome instability in ovarian cancer cell lines and primary patient samples
- (2017) Signe Penner-Goeke et al. PLoS Genetics
- CCNE1 amplification and centrosome number abnormality in serous tubal intraepithelial carcinoma: further evidence supporting its role as a precursor of ovarian high-grade serous carcinoma
- (2016) Elisabetta Kuhn et al. MODERN PATHOLOGY
- Chromosome instability drives phenotypic switching to metastasis
- (2016) ChongFeng Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CENP-A K124 Ubiquitylation Is Required for CENP-A Deposition at the Centromere
- (2015) Yohei Niikura et al. DEVELOPMENTAL CELL
- A mechanism for the suppression of homologous recombination in G1 cells
- (2015) Alexandre Orthwein et al. NATURE
- YAP induces high-grade serous carcinoma in fallopian tube secretory epithelial cells
- (2015) G Hua et al. ONCOGENE
- Targeting SOD1 induces synthetic lethal killing in BLM- and CHEK2-deficient colorectal cancer cells
- (2015) Babu V. Sajesh et al. Oncotarget
- A Novel Multiplexed, Image-Based Approach to Detect Phenotypes That Underlie Chromosome Instability in Human Cells
- (2015) Laura L. Thompson et al. PLoS One
- Molecular Requirements for Transformation of Fallopian Tube Epithelial Cells into Serous Carcinoma
- (2015) Amir A. Jazaeri et al. NEOPLASIA
- Mechanisms of chromosomal instability in melanoma
- (2014) William K. Kaufmann et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Expression and prognostic relevance of centromere protein A in primary osteosarcoma
- (2014) Xiao-Min Gu et al. PATHOLOGY RESEARCH AND PRACTICE
- Unique Pattern of Component Gene Disruption in the NRF2 Inhibitor KEAP1/CUL3/RBX1 E3-Ubiquitin Ligase Complex in Serous Ovarian Cancer
- (2014) Victor D. Martinez et al. Biomed Research International
- The Soft Agar Colony Formation Assay
- (2014) Stanley Borowicz et al. Jove-Journal of Visualized Experiments
- Sister chromatid cohesion defects are associated with chromosome instability in Hodgkin lymphoma cells
- (2013) Babu V Sajesh et al. BMC CANCER
- Transformation of the Fallopian Tube Secretory Epithelium Leads to High-Grade Serous Ovarian Cancer in Brca;Tp53;Pten Models
- (2013) Ruth Perets et al. CANCER CELL
- Cyclin E1 Deregulation Occurs Early in Secretory Cell Transformation to Promote Formation of Fallopian Tube-Derived High-Grade Serous Ovarian Cancers
- (2013) A. M. Karst et al. CANCER RESEARCH
- Synthetic Lethal Targeting of Superoxide Dismutase 1 Selectively Kills RAD54B -Deficient Colorectal Cancer Cells
- (2013) Babu V. Sajesh et al. GENETICS
- Overexpression of RING box protein-1 (RBX1) associated with poor prognosis of non-muscle-invasive bladder transitional cell carcinoma
- (2013) Wei Wang et al. JOURNAL OF SURGICAL ONCOLOGY
- SCFs in the new millennium
- (2013) E K Lee et al. ONCOGENE
- Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion
- (2013) T-V Do et al. ONCOGENE
- Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
- (2013) J. Gao et al. Science Signaling
- Endoreplication
- (2013) N. Zielke et al. Cold Spring Harbor Perspectives in Biology
- Cancer Karyotypes: Survival of the Fittest
- (2013) Joshua M. Nicholson et al. Frontiers in Oncology
- A Double-Edged Sword: How Oncogenes and Tumor Suppressor Genes Can Contribute to Chromosomal Instability
- (2013) Bernardo Orr et al. Frontiers in Oncology
- Cancer cell micronucleus: an update on clinical and diagnostic applications
- (2012) Alka Bhatia et al. APMIS
- Nonsense-mediated mRNA decay: from mechanistic insights to impacts on human health
- (2012) I. M. Palacios Briefings in Functional Genomics
- Induction of autophagy and senescence by knockdown of ROC1 E3 ubiquitin ligase to suppress the growth of liver cancer cells
- (2012) D Yang et al. CELL DEATH AND DIFFERENTIATION
- MDC1 and RNF8 function in a pathway that directs BRCA1-dependent localization of PALB2 required for homologous recombination
- (2012) F. Zhang et al. JOURNAL OF CELL SCIENCE
- Expression and prognostic significance of centromere protein A in human lung adenocarcinoma
- (2012) Qing Wu et al. LUNG CANCER
- Primary culture and immortalization of human fallopian tube secretory epithelial cells
- (2012) Alison M Karst et al. Nature Protocols
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- CRL Ubiquitin Ligases and DNA Damage Response
- (2012) Ju-Mei Li et al. Frontiers in Oncology
- The Causes and Consequences of Polyploidy in Normal Development and Cancer
- (2011) Teresa Davoli et al. Annual Review of Cell and Developmental Biology
- Chromosomal Instability Confers Intrinsic Multidrug Resistance
- (2011) A. J. X. Lee et al. CANCER RESEARCH
- Detecting UV-lesions in the genome: The modular CRL4 ubiquitin ligase does it best!
- (2011) Andrea Scrima et al. FEBS LETTERS
- Integrated genomic analyses of ovarian carcinoma
- (2011) D. Bell et al. NATURE
- Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
- (2011) A. M. Karst et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A
- (2011) S. Moghe et al. Biology Open
- Aurora-A overexpression and aneuploidy predict poor outcome in serous ovarian carcinoma
- (2010) Heini Lassus et al. GYNECOLOGIC ONCOLOGY
- Specific Overexpression of Cyclin E·CDK2 in Early Preinvasive and Primary Breast Tumors in Female ACI Rats Induced by Estrogen
- (2010) S. John Weroha et al. Hormones & Cancer
- RING Domain E3 Ubiquitin Ligases
- (2009) Raymond J. Deshaies et al. Annual Review of Biochemistry
- ROC1/RBX1 E3 Ubiquitin Ligase Silencing Suppresses Tumor Cell Growth via Sequential Induction of G2-M Arrest, Apoptosis, and Senescence
- (2009) L. Jia et al. CANCER RESEARCH
- SnapShot: F Box Proteins I
- (2009) Jeffrey R. Skaar et al. CELL
- PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response
- (2009) Feng Zhang et al. CURRENT BIOLOGY
- CENPA overexpression promotes genome instability in pRb-depleted human cells
- (2009) Angela Amato et al. Molecular Cancer
- RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27
- (2009) M. Tan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PALB2 is an integral component of the BRCA complex required for homologous recombination repair
- (2009) S. M. H. Sy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival
- (2009) Lijun Jia et al. Cell Division
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy
- (2008) S Finkin et al. ONCOGENE
- Roles of cyclins A and E in induction of centrosome amplification in p53-compromised cells
- (2008) K Hanashiro et al. ONCOGENE
- Defining ‘chromosomal instability’
- (2008) Jochen B. Geigl et al. TRENDS IN GENETICS
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