The Causes and Consequences of Polyploidy in Normal Development and Cancer

Molecular Genetics of Colorectal Cancer

(2011) Eric R. Fearon   Annual Review of Pathology-Mechanisms of Disease

p53 and MDM2 in renal cell carcinoma

(2010) Aidan P. Noon et al.   CANCER

Stepwise progression of pulmonary adenocarcinoma—clinical and molecular implications

(2010) Masayuki Noguchi   CANCER AND METASTASIS REVIEWS

Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence

(2010) Agustin Chicas et al.   CANCER CELL

Dysregulation of cellular signaling in gastric cancer

(2010) William K.K. Wu et al.   CANCER LETTERS

Persistent Telomere Damage Induces Bypass of Mitosis and Tetraploidy

(2010) Teresa Davoli et al.   CELL

Developmentally programmed endoreduplication in animals

(2010) Zakir Ullah et al.   CELL CYCLE

Polyploidy and liver proliferation: Central role of insulin signaling

(2010) Séverine Celton-Morizur et al.   CELL CYCLE

Mechanisms of Chromosomal Instability

(2010) Sarah L. Thompson et al.   CURRENT BIOLOGY

Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive

(2010) C. H. Coschi et al.   GENES & DEVELOPMENT

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling

(2010) T. van Harn et al.   GENES & DEVELOPMENT

Loss of pRB causes centromere dysfunction and chromosomal instability

(2010) A. L. Manning et al.   GENES & DEVELOPMENT

Mad2 inhibits the mitotic kinesin MKlp2

(2010) Sang Hyun Lee et al.   JOURNAL OF CELL BIOLOGY

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

The ploidy conveyor of mature hepatocytes as a source of genetic variation

(2010) Andrew W. Duncan et al.   NATURE

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol

(2010) S Radulescu et al.   ONCOGENE

High-risk HPV E5-induced cell fusion: a critical initiating event in the early stage of HPV-associated cervical cancer

(2010) Peng Gao et al.   Virology Journal

The Pathobiology of Glioma Tumors

(2009) Candece L. Gladson et al.   Annual Review of Pathology-Mechanisms of Disease

Centrosomes and cancer: how cancer cells divide with too many centrosomes

(2009) Susana A. Godinho et al.   CANCER AND METASTASIS REVIEWS

Escape from p53-mediated tumor surveillance in neuroblastoma: switching off the p14ARF-MDM2-p53 axis

(2009) T Van Maerken et al.   CELL DEATH AND DIFFERENTIATION

Eukaryotic DNA replication control: Lock and load, then fire

(2009) Dirk Remus et al.   CURRENT OPINION IN CELL BIOLOGY

Endoreplication: polyploidy with purpose

(2009) H. O. Lee et al.   GENES & DEVELOPMENT

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

The evolutionary significance of ancient genome duplications

(2009) Yves Van de Peer et al.   NATURE REVIEWS GENETICS

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

How Telomeres Solve the End-Protection Problem

(2009) T. de Lange   SCIENCE

Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy

(2009) Zakir Ullah et al.   Cell Division

Ploidy Reductions in Murine Fusion-Derived Hepatocytes

(2009) Andrew W. Duncan et al.   PLoS Genetics

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

Pancreatic Cancer

(2008) Anirban Maitra et al.   Annual Review of Pathology-Mechanisms of Disease

Molecular Pathogenesis of Cutaneous Melanocytic Neoplasms

(2008) Nageatte Ibrahim et al.   Annual Review of Pathology-Mechanisms of Disease

Molecular Pathogenesis and Diagnostics of Bladder Cancer

(2008) Anirban P. Mitra et al.   Annual Review of Pathology-Mechanisms of Disease

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

(2008) M. Kwon et al.   GENES & DEVELOPMENT

Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity

(2008) Z. Ullah et al.   GENES & DEVELOPMENT

Clinicopathologic significance of mitotic arrest defective protein 2 overexpression in hepatocellular carcinoma

(2008) Shu-Hui Zhang et al.   HUMAN PATHOLOGY

The consequences of tetraploidy and aneuploidy

(2008) Z. Storchova et al.   JOURNAL OF CELL SCIENCE

Telomeres and Telomerase in Lung Cancer

(2008) Ignacio Fernandez-Garcia et al.   Journal of Thoracic Oncology

Human papillomavirus 16 E5 induces bi-nucleated cell formation by cell–cell fusion

(2008) Lulin Hu et al.   VIROLOGY

Tumor suppressor and hepatocellular carcinoma

(2008) Juliette Martin   WORLD JOURNAL OF GASTROENTEROLOGY