DOTAM-Based, Targeted, Activatable Fluorescent Probes for the Highly Sensitive and Selective Detection of Cancer Cells

Fluorescence imaging of drug target proteins using chemical probes

(2020) Hao Zhu et al.   Journal of Pharmaceutical Analysis

Design, Synthesis, and Application of a Small Molecular NIR-II Fluorophore with Maximal Emission beyond 1200 nm

(2020) Yu Fang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recognition Moieties of Small Molecular Fluorescent Probes for Bioimaging of Enzymes

(2019) Xiaofeng Wu et al.   ACCOUNTS OF CHEMICAL RESEARCH

The scope of application of macrocyclic polyamines beyond metal chelation

(2019) Pauline Lejault et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Size‐dependent Cellular Uptake of RGD Peptides

(2019) Isabell Kemker et al.   CHEMBIOCHEM

Small Molecule as Fluorescent Probes for Monitoring Intracellular Enzymatic Transformations

(2019) Harwinder Singh et al.   CHEMICAL REVIEWS

Enzyme-Activated Fluorogenic Probes for Live-Cell and in Vivo Imaging

(2018) Wen Chyan et al.   ACS Chemical Biology

Optical molecular imaging for tumor detection and image-guided surgery

(2018) Chensu Wang et al.   BIOMATERIALS

Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

(2018) Hong-Wen Liu et al.   CHEMICAL SOCIETY REVIEWS

Novel Linear Peptides with High Affinity to αvβ3 Integrin for Precise Tumor Identification

(2017) Yi Ma et al.   Theranostics

Exploring the Role of RGD-Recognizing Integrins in Cancer

(2017) Markus Nieberler et al.   Cancers

Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families

(2017) Marcin Poreba et al.   Scientific Reports

The complexity of integrins in cancer and new scopes for therapeutic targeting

(2016) Hellyeh Hamidi et al.   BRITISH JOURNAL OF CANCER

A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer

(2016) Melodi Javid Whitley et al.   Science Translational Medicine

DOTAM Derivatives as Active Cartilage-Targeting Drug Carriers for the Treatment of Osteoarthritis

(2015) Hai-Yu Hu et al.   BIOCONJUGATE CHEMISTRY

Cathepsin S: therapeutic, diagnostic, and prognostic potential

(2015) Richard D.A. Wilkinson et al.   BIOLOGICAL CHEMISTRY

Design of a Highly Selective Quenched Activity-Based Probe and Its Application in Dual Color Imaging Studies of Cathepsin S Activity Localization

(2015) Kristina Oresic Bender et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In vivo visualization of osteoarthritic hypertrophic lesions

(2015) Hai-Yu Hu et al.   Chemical Science

Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes

(2015) Reik Löser et al.   Frontiers in Chemistry

In Vivo Imaging of Mouse Tumors by a Lipidated Cathepsin S Substrate

(2014) Hai-Yu Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An intracellularly activatable, fluorogenic probe for cancer imaging

(2014) Ruisong Tian et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Molecular imaging for cancer diagnosis and surgery

(2013) Timon Hussain et al.   ADVANCED DRUG DELIVERY REVIEWS

Cathepsin S inhibition suppresses systemic lupus erythematosus and lupus nephritis because cathepsin S is essential for MHC class II-mediated CD4 T cell and B cell priming

(2013) Khader Valli Rupanagudi et al.   ANNALS OF THE RHEUMATIC DISEASES

Non-invasive molecular imaging for preclinical cancer therapeutic development

(2013) AC O'Farrell et al.   BRITISH JOURNAL OF PHARMACOLOGY

The ubiquitous DOTA and its derivatives: the impact of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid on biomedical imaging

(2013) Graeme J. Stasiuk et al.   CHEMICAL COMMUNICATIONS

Radioactive Smart Probe for Potential Corrected Matrix Metalloproteinase Imaging

(2012) Chiun-Wei Huang et al.   BIOCONJUGATE CHEMISTRY

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

(2012) Fabienne Danhier et al.   MOLECULAR PHARMACEUTICS

Advances in molecular imaging: targeted optical contrast agents for cancer diagnostics

(2012) Anne Hellebust et al.   Nanomedicine

Integrin Targeting for Tumor Optical Imaging

(2012) Yunpeng Ye et al.   Theranostics

Cysteine cathepsins: From structure, function and regulation to new frontiers

(2011) Vito Turk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Dual-Functional, Receptor-Targeted Fluorogenic Probe for In Vivo Imaging of Extracellular Protease Expressions

(2011) Lei Zhu et al.   BIOCONJUGATE CHEMISTRY

Macrocyclic chelator assembled RGD multimers for tumor targeting

(2011) Xiaofen Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Differences in integrin expression and signaling within human breast cancer cells

(2011) Aliakbar Taherian et al.   BMC CANCER

Non-Invasive Imaging of Cysteine Cathepsin Activity in Solid Tumors Using a 64Cu-Labeled Activity-Based Probe

(2011) Gang Ren et al.   PLoS One

Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation

(2010) Dejan Caglič et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival

(2010) Q. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Improved Cell-Penetrating, Caspase-Activatable, Near-Infrared Fluorescent Peptide for Apoptosis Imaging

(2009) Dustin Maxwell et al.   BIOCONJUGATE CHEMISTRY

Complementary optical and nuclear imaging of caspase-3 activity using combined activatable and radio-labeled multimodality molecular probe

(2009) Hyeran Lee et al.   JOURNAL OF BIOMEDICAL OPTICS

Clustering and Internalization of Integrin αvβ3 With a Tetrameric RGD-synthetic Peptide

(2009) Sancey Lucie et al.   MOLECULAR THERAPY

Binding and Uptake of RGD-Containing Ligands to Cellular α v β 3 Integrins

(2008) Sonya Cressman et al.   International Journal of Peptide Research and Therapeutics

Selective Activity-Based Probes for Cysteine Cathepsins

(2007) Anja Watzke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION