Endothelial nitric oxide synthase deficient mice: a model of spontaneous cerebral small vessel disease

APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

(2020) Axel Montagne et al.   NATURE

Myelination in Multiple Sclerosis Lesions Is Associated with Regulation of Bone Morphogenetic Protein 4 and Its Antagonist Noggin

(2019) Kim Harnisch et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction

(2019) Daniel A. Nation et al.   NATURE MEDICINE

Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

(2019) Angeliki M. Nikolakopoulou et al.   NATURE NEUROSCIENCE

Cerebral Small Vessel Disease (CSVD) – Lessons From the Animal Models

(2019) Muzaimi Mustapha et al.   Frontiers in Physiology

Blood–brain barrier leakage in relation to white matter hyperintensity volume and cognition in small vessel disease and normal aging

(2018) C. Eleana Zhang et al.   Brain Imaging and Behavior

Understanding the role of the perivascular space in cerebral small vessel disease

(2018) Rosalind Brown et al.   CARDIOVASCULAR RESEARCH

White matter degeneration in vascular and other ageing-related dementias

(2018) Yoshiki Hase et al.   JOURNAL OF NEUROCHEMISTRY

Pericyte degeneration causes white matter dysfunction in the mouse central nervous system

(2018) Axel Montagne et al.   NATURE MEDICINE

Rodent Models of Cerebral Microinfarct and Microhemorrhage

(2018) Andy Y. Shih et al.   STROKE

Cerebral Perfusion Insufficiency and Relationships with Cognitive Deficits in Alzheimer’s Disease: A Multiparametric Neuroimaging Study

(2018) Chi-Wei Huang et al.   Scientific Reports

Targeting pericytes for therapeutic approaches to neurological disorders

(2018) Jinping Cheng et al.   ACTA NEUROPATHOLOGICA

Effects of Hypoperfusion in Alzheimer's Disease

(2018) Benjamin P. Austin et al.   JOURNAL OF ALZHEIMERS DISEASE

Endothelial NOS: perspective and recent developments

(2018) Victor Garcia et al.   BRITISH JOURNAL OF PHARMACOLOGY

Blood-Brain Barrier: From Physiology to Disease and Back

(2018) Melanie D. Sweeney et al.   PHYSIOLOGICAL REVIEWS

How Do Cells of the Oligodendrocyte Lineage Affect Neuronal Circuits to Influence Motor Function, Memory and Mood?

(2018) Renee E. Pepper et al.   Frontiers in Cellular Neuroscience

Functional deficits induced by cortical microinfarcts

(2017) Philipp M Summers et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Does pathology of small venules contribute to cerebral microinfarcts and dementia?

(2017) David A. Hartmann et al.   JOURNAL OF NEUROCHEMISTRY

On Myelinated Axon Plasticity and Neuronal Circuit Formation and Function

(2017) Rafael G. Almeida et al.   JOURNAL OF NEUROSCIENCE

Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease

(2016) Harm J. van de Haar et al.   RADIOLOGY

Vascular contributions to cognitive impairment and dementia including Alzheimer's disease

(2015) Heather M. Snyder et al.   Alzheimers & Dementia

HeterozygousHTRA1mutations are associated with autosomal dominant cerebral small vessel disease

(2015) Edgard Verdura et al.   BRAIN

Cardiovascular risk factors and small vessel disease of the brain: Blood pressure, white matter lesions, and functional decline in older persons

(2015) Hazel Mae A Abraham et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Partial eNOS deficiency causes spontaneous thrombotic cerebral infarction, amyloid angiopathy and cognitive impairment

(2015) Xing-Lin Tan et al.   Molecular Neurodegeneration

The Corticohippocampal Circuit, Synaptic Plasticity, and Memory

(2015) Jayeeta Basu et al.   Cold Spring Harbor Perspectives in Biology

The overlap between vascular disease and Alzheimer’s disease - lessons from pathology

(2014) Johannes Attems et al.   BMC Medicine

Pyramidal neurons of the prefrontal cortex in post-stroke, vascular and other ageing-related dementias

(2014) Vincent Foster et al.   BRAIN

Imaging of cerebrovascular pathology in animal models of Alzheimer's disease

(2014) Jan Klohs et al.   Frontiers in Aging Neuroscience

Metabolic Stress Modulates Alzheimer’s β-Secretase Gene Transcription via SIRT1-PPARγ-PGC-1 in Neurons

(2013) Ruishan Wang et al.   Cell Metabolism

Endothelial nitric oxide deficiency promotes Alzheimer's disease pathology

(2013) Susan A. Austin et al.   JOURNAL OF NEUROCHEMISTRY

Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

The Pathobiology of Vascular Dementia

(2013) Costantino Iadecola   NEURON

The role of nitric oxide in pre-synaptic plasticity and homeostasis

(2013) Neil Hardingham et al.   Frontiers in Cellular Neuroscience

Cerebral microinfarcts: the invisible lesions

(2012) Eric E Smith et al.   LANCET NEUROLOGY

Blood–Brain Barrier Permeability and Long-Term Clinical and Imaging Outcomes in Cerebral Small Vessel Disease

(2012) Joanna M. Wardlaw et al.   STROKE

Cerebral amyloid angiopathy in the elderly

(2011) Anand Viswanathan et al.   ANNALS OF NEUROLOGY

2001–2011: A Decade of the LADIS (Leukoaraiosis And DISability) Study: What Have We Learned about White Matter Changes and Small-Vessel Disease?

(2011)   CEREBROVASCULAR DISEASES

Rapid Disruption of Axon-Glial Integrity in Response to Mild Cerebral Hypoperfusion

(2011) M. M. Reimer et al.   JOURNAL OF NEUROSCIENCE

Differential regulation of BACE1 expression by oxidative and nitrosative signals

(2011) Young-Don Kwak et al.   Molecular Neurodegeneration

The 894G > T (Glu298Asp) Variant in the Endothelial NOS Gene and MTHFR Polymorphisms Influence Homocysteine Levels in Patients with Cognitive Decline

(2011) Nadia Ferlazzo et al.   NEUROMOLECULAR MEDICINE

Blood–Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease

(2011) Yi Yang et al.   STROKE

Microinfarct Pathology, Dementia, and Cognitive Systems

(2011) Zoe Arvanitakis et al.   STROKE

Cells of the oligodendroglial lineage, myelination, and remyelination

(2010) Veronique E. Miron et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Endothelial Nitric Oxide Synthase Deficiency Causes Collateral Vessel Rarefaction and Impairs Activation of a Cell Cycle Gene Network During Arteriogenesis

(2010) Xuming Dai et al.   CIRCULATION RESEARCH

Bmp4-directed nuclear cyan fluorescent protein provides a tool for live imaging and reveals cellular resolution of Bmp4 expression patterns during embryogenesis

(2010) Chuan-Wei Jang et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges

(2010) Leonardo Pantoni   LANCET NEUROLOGY

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Distinct cerebral perfusion patterns in FTLD and AD

(2010) W. T. Hu et al.   NEUROLOGY

Alterations of the blood–brain barrier in cerebral white matter lesions in the ageing brain

(2010) Julie E. Simpson et al.   NEUROSCIENCE LETTERS

Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice

(2010) Mattias Carlström et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lacunar stroke is associated with diffuse blood-brain barrier dysfunction

(2009) Joanna M. Wardlaw et al.   ANNALS OF NEUROLOGY

Role of endothelial nitric oxide synthetase in arteriogenesis after stroke in mice

(2009) X. Cui et al.   NEUROSCIENCE

Significant negative correlations between capillary expressed eNOS and Alzheimer lesion burden

(2009) Brian Jeynes et al.   NEUROSCIENCE LETTERS

eNOS, metabolic syndrome and cardiovascular disease

(2009) Paul L. Huang   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Role of transforming growth factor-β superfamily signaling pathways in human disease

(2008) Kelly J. Gordon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis

(2007) Andrew J. Farrall et al.   NEUROBIOLOGY OF AGING