Development of Non-Porous Silica Nanoparticles towards Cancer Photo-Theranostics

Nanomaterials for Nanotheranostics: Tuning Their Properties According to Disease Needs

(2020) Xin Yi Wong et al.   ACS Nano

Highly Stabilized Gradient Alloy Quantum Dots and Silica Hybrid Nanospheres by Core Double Shells for Photoluminescence Devices

(2020) Hongxing Xie et al.   Journal of Physical Chemistry Letters

Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges

(2020) John D. Martin et al.   Nature Reviews Clinical Oncology

Fucoidan-Based Theranostic Nanogel for Enhancing Imaging and Photodynamic Therapy of Cancer

(2020) Mi Hyeon Cho et al.   Nano-Micro Letters

Nanoarchitectured Structure and Surface Biofunctionality of Mesoporous Silica Nanoparticles

(2020) Ranjith Kumar Kankala et al.   ADVANCED MATERIALS

One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility

(2020) Raziye Mohammadpour et al.   JOURNAL OF CONTROLLED RELEASE

Cancer therapy with iron oxide nanoparticles: Agents of thermal and immune therapies

(2020) Frederik Soetaert et al.   ADVANCED DRUG DELIVERY REVIEWS

Photoactivatable Protherapeutic Nanomedicine for Cancer

(2020) Yan Zhang et al.   ADVANCED MATERIALS

Application of mesoporous silica nanoparticles as drug delivery carriers for chemotherapeutic agents

(2020) Yasmine Alyassin et al.   DRUG DISCOVERY TODAY

Targeted antimicrobial peptide delivery in vivo to tumor with near infrared photoactivated mesoporous silica nanoparticles

(2020) Weibing Dong et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Clinical development and potential of photothermal and photodynamic therapies for cancer

(2020) Xingshu Li et al.   Nature Reviews Clinical Oncology

Tumor‐Targeting Glycol Chitosan Nanoparticles for Cancer Heterogeneity

(2020) Ju Hee Ryu et al.   ADVANCED MATERIALS

Advances in nanomedicines for diagnosis of central nervous system disorders

(2020) Xun Zhang et al.   BIOMATERIALS

Near-Infrared Fluorescent Thiol-Organosilica Nanoparticles That Are Functionalized with IR-820 and Their Applications for Long-Term Imaging of in Situ Labeled Cells and Depth-Dependent Tumor in Vivo Imaging

(2020) Michihiro Nakamura et al.   CHEMISTRY OF MATERIALS

The cost-effectiveness of TheraSphere in patients with hepatocellular carcinoma who are eligible for transarterial embolization

(2020) Derek Manas et al.   EJSO

Cancer Nanomedicines in an Evolving Oncology Landscape

(2020) Peng Guo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Dye‐Loaded Nanoemulsions: Biomimetic Fluorescent Nanocarriers for Bioimaging and Nanomedicine

(2020) Andrey S. Klymchenko et al.   Advanced Healthcare Materials

Comparison of Iron Oxide Nanoparticles in Photothermia and Magnetic Hyperthermia: Effects of Clustering and Silica Encapsulation on Nanoparticles’ Heating Yield

(2020) Sebastjan Nemec et al.   Applied Sciences-Basel

Progress in Clinical Trials of Photodynamic Therapy for Solid Tumors and the Role of Nanomedicine

(2020) Hashem O. Alsaab et al.   Cancers

Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicines

(2020) Alejandro Baeza et al.   Pharmaceutics

Enhancement of tumour penetration by nanomedicines through strategies based on transport processes and barriers

(2020) Huang Yang et al.   JOURNAL OF CONTROLLED RELEASE

Relationship between the glutathione-responsive degradability of thiol-organosilica nanoparticles and the chemical structures

(2019) Tomohiro Doura et al.   JOURNAL OF MATERIALS RESEARCH

Recent advancements in mesoporous silica nanoparticles towards therapeutic applications for cancer

(2019) Tingting Li et al.   Acta Biomaterialia

Reactive Oxygen Species (ROS)-Based Nanomedicine

(2019) Bowen Yang et al.   CHEMICAL REVIEWS

Cancer nanomedicine for combination cancer immunotherapy

(2019) Jutaek Nam et al.   Nature Reviews Materials

Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery

(2019) Nishtha Panwar et al.   CHEMICAL REVIEWS

Subchronic toxicity of silica nanoparticles as a function of size and porosity

(2019) Raziye Mohammadpour et al.   JOURNAL OF CONTROLLED RELEASE

Functionalized mesoporous silica nanoparticles and biomedical applications

(2019) Thai Thanh Hoang Thi et al.   Materials Science & Engineering C-Materials for Biological Applications

Quantum dots from microfluidics for nanomedical application

(2019) Feika Bian et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Functionalized mesoporous silica nanoparticles in anticancer therapeutics

(2019) Abul Barkat et al.   SEMINARS IN CANCER BIOLOGY

In vitro and in vivo evaluation of degradation, toxicity, biodistribution, and clearance of silica nanoparticles as a function of size, porosity, density, and composition

(2019) Seyyed Pouya Hadipour Moghaddam et al.   JOURNAL OF CONTROLLED RELEASE

Smart cancer nanomedicine

(2019) Roy van der Meel et al.   Nature Nanotechnology

Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy

(2019) Liping Huang et al.   Nature Communications

Ultrasmall PEGylated and Targeted Core–Shell Silica Nanoparticles Carrying Methylene Blue Photosensitizer

(2019) Ferdinand F. E. Kohle et al.   ACS Biomaterials-Science & Engineering

Tau-Targeted Multifunctional Nanocomposite for Combinational Therapy of Alzheimer’s Disease

(2018) Qing Chen et al.   ACS Nano

Multimodality Imaging of Silica and Silicon Materials In Vivo

(2018) Didem Şen Karaman et al.   ADVANCED MATERIALS

Block Copolymer Micelles in Nanomedicine Applications

(2018) Horacio Cabral et al.   CHEMICAL REVIEWS

Silica@layered double hydroxide core–shell hybrid materials

(2018) Wing L. J. Kwok et al.   DALTON TRANSACTIONS

A new class of cubic SPIONs as a dual-mode T1 and T2 contrast agent for MRI

(2018) Akbar Alipour et al.   MAGNETIC RESONANCE IMAGING

Dual-Modal NIR-Fluorophore Conjugated Magnetic Nanoparticle for Imaging Amyloid-β Species In Vivo

(2018) Yinhui Li et al.   Small

A New Treatment Modality for Rheumatoid Arthritis: Combined Photothermal and Photodynamic Therapy Using Cu7.2 S4 Nanoparticles

(2018) Yao Lu et al.   Advanced Healthcare Materials

Two-Photon-Excited Silica and Organosilica Nanoparticles for Spatiotemporal Cancer Treatment

(2018) Jonas G. Croissant et al.   Advanced Healthcare Materials

Polysiloxanes in Theranostics and Drug Delivery: A Review

(2018) Ignazio Blanco   Polymers

Iron Oxide and Gold Based Magneto-Plasmonic Nanostructures for Medical Applications: A Review

(2018) Thi Nguyen et al.   Nanomaterials

Synthesis and Biomedical Applications of Multifunctional Nanoparticles

(2018) Dokyoon Kim et al.   ADVANCED MATERIALS

AGuIX® from bench to bedside—Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine

(2018) François Lux et al.   BRITISH JOURNAL OF RADIOLOGY

Nanoparticle-Mediated Remodeling of the Tumor Microenvironment to Enhance Immunotherapy

(2018) Sara Musetti et al.   ACS Nano

Synthesis and stability of IR-820 and FITC doped silica nanoparticles

(2017) Atul V. Thorat et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Relaxometric property of organosilica nanoparticles internally functionalized with iron oxide and fluorescent dye for multimodal imaging

(2017) Michihiro Nakamura et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Ultrasmall Silica-Based Bismuth Gadolinium Nanoparticles for Dual Magnetic Resonance–Computed Tomography Image Guided Radiation Therapy

(2017) Alexandre Detappe et al.   NANO LETTERS

Multifunctional nanoparticles as a tissue adhesive and an injectable marker for image-guided procedures

(2017) Kwangsoo Shin et al.   Nature Communications

Improving the brightness and photostability of NIR fluorescent silica nanoparticles through rational fine-tuning of the covalent encapsulation methods

(2017) Long Jiao et al.   Journal of Materials Chemistry B

Mesoscopic Multimodal Imaging Provides New Insight to Tumor Tissue Evaluation: An Example of Macrophage Imaging of Hepatic Tumor using Organosilica Nanoparticles

(2017) Michihiro Nakamura et al.   Scientific Reports

Rare Earth Doped Silica Nanoparticles via Thermolysis of a Single Source Metallasilsesquioxane Precursor

(2017) Gemma-Louise Davies et al.   Scientific Reports

Sensitive imaging and effective capture of Cu 2+ : Towards highly efficient theranostics of Alzheimer's disease

(2016) Zhaowen Cui et al.   BIOMATERIALS

Multifunctional organically modified silica nanoparticles for chemotherapy, adjuvant hyperthermia and near infrared imaging

(2016) Abhignyan Nagesetti et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

In Vivo Targeting and Imaging of Atherosclerosis Using Multifunctional Virus-Like Particles of Simian Virus 40

(2016) Xianxun Sun et al.   NANO LETTERS

Stable Radiolabeling of Sulfur-Functionalized Silica Nanoparticles with Copper-64

(2016) Travis M. Shaffer et al.   NANO LETTERS

Nanomedicine strategies to overcome the pathophysiological barriers of pancreatic cancer

(2016) Pavan P. Adiseshaiah et al.   Nature Reviews Clinical Oncology

Gadolinium-Based Nanoparticles and Radiation Therapy for Multiple Brain Melanoma Metastases: Proof of Concept before Phase I Trial

(2016) Shady Kotb et al.   Theranostics

A Novel Electrochemiluminescence Immunosensor for the Analysis of HIV-1 p24 Antigen Based on P-RGO@Au@Ru-SiO2 Composite

(2015) Limin Zhou et al.   ACS Applied Materials & Interfaces

Identification of Polyethylene Glycol-Resistant Macrophages on Stealth Imaging in Vitro Using Fluorescent Organosilica Nanoparticles

(2015) Michihiro Nakamura et al.   ACS Nano

Development of mesoporous silica-based nanoparticles with controlled release capability for cancer therapy

(2015) Harutaka Mekaru et al.   ADVANCED DRUG DELIVERY REVIEWS

Drug-loaded gold/iron/gold plasmonic nanoparticles for magnetic targeted chemo-photothermal treatment of rheumatoid arthritis

(2015) Hyung Joon Kim et al.   BIOMATERIALS

Effect of doping Gd3+ on crystal structure and luminescent properties of Sr2SiO4:Eu2+ phosphor

(2015) Cong ZHAO et al.   JOURNAL OF RARE EARTHS

Personalizing Biomaterials for Precision Nanomedicine Considering the Local Tissue Microenvironment

(2015) Nuria Oliva et al.   Advanced Healthcare Materials

A Silica–Gold–Silica Nanocomposite for Photothermal Therapy in the Near-Infrared Region

(2014) Song Liang et al.   ACS Applied Materials & Interfaces

Iron/iron oxide core/shell nanoparticles for magnetic targeting MRI and near-infrared photothermal therapy

(2014) Zhiguo Zhou et al.   BIOMATERIALS

Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

(2014) E. Phillips et al.   Science Translational Medicine

Gold nanoparticle cluster–plasmon-enhanced fluorescent silica core–shell nanoparticles for X-ray computed tomography–fluorescence dual-mode imaging of tumors

(2013) Koichiro Hayashi et al.   CHEMICAL COMMUNICATIONS

A Top-Down Synthesis Route to Ultrasmall Multifunctional Gd-Based Silica Nanoparticles for Theranostic Applications

(2013) Anna Mignot et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nonporous silica nanoparticles for nanomedicine application

(2013) Li Tang et al.   Nano Today

Upconverting Organic Dye Doped Core-Shell Nano-Composites for Dual-Modality NIR Imaging and Photo-Thermal Therapy

(2013) Guobin Shan et al.   Theranostics

Synthesis and Biological Response of Size-Specific, Monodisperse Drug–Silica Nanoconjugates

(2012) Li Tang et al.   ACS Nano

Ultrasensitive, Biocompatible, Quantum-Dot-Embedded Silica Nanoparticles for Bioimaging

(2012) Bong-Hyun Jun et al.   ADVANCED FUNCTIONAL MATERIALS

Photosensitizer encapsulated organically modified silica nanoparticles for direct two-photon photodynamic therapy and In Vivo functional imaging

(2012) Jun Qian et al.   BIOMATERIALS

MUC-1 aptamer-conjugated dye-doped silica nanoparticles for MCF-7 cells detection

(2012) Li Cai et al.   BIOMATERIALS

Covalent conjugation of avidin with dye-doped silica nanopaticles and preparation of high density avidin nanoparticles as photostable bioprobes

(2012) Ze-Zhong Chen et al.   BIOSENSORS & BIOELECTRONICS

Silica–porphyrin hybrid nanotubes for in vivo cell tracking by near-infrared fluorescence imaging

(2012) Koichiro Hayashi et al.   CHEMICAL COMMUNICATIONS

Thiol-Organosilica Particles Internally Functionalized with Propidium Iodide as a Multicolor Fluorescence and X-ray Computed Tomography Probe and Application for Non-Invasive Functional Gastrointestinal Tract Imaging

(2012) Michihiro Nakamura et al.   CHEMISTRY OF MATERIALS

Fe3O4@SiO2 Core/Shell Nanoparticles: The Silica Coating Regulations with a Single Core for Different Core Sizes and Shell Thicknesses

(2012) H. L. Ding et al.   CHEMISTRY OF MATERIALS

Dye Doped Eosin Yellowish Silica Nanoparticles as Novel Fluorophore for a Peroxyoxalate Chemiluminescence System

(2012) Abdollah Yari et al.   JOURNAL OF FLUORESCENCE

Synthesis of Silica Nanoparticles by Sol-Gel: Size-Dependent Properties, Surface Modification, and Applications in Silica-Polymer Nanocomposites—A Review

(2012) Ismail Ab Rahman et al.   Journal of Nanomaterials

Time-lapse fluorescence imaging and quantitative single cell and endosomal analysis of peritoneal macrophages using fluorescent organosilica nanoparticles

(2012) Michihiro Nakamura et al.   Nanomedicine-Nanotechnology Biology and Medicine

Fluorescent Silica Nanoparticles Improve Optical Imaging of Stem Cells Allowing Direct Discrimination between Live and Early-Stage Apoptotic Cells

(2012) Lisa Accomasso et al.   Small

Near infrared dye indocyanine green doped silica nanoparticles for biological imaging

(2012) Bo Quan et al.   TALANTA

Near-Infrared Fluorescent Silica-Coated Gold Nanoparticle Clusters for X-Ray Computed Tomography/Optical Dual Modal Imaging of the Lymphatic System

(2012) Koichiro Hayashi et al.   Advanced Healthcare Materials

Biomedical applications of organosilica nanoparticles toward theranostics

(2012) Michihiro Nakamura   Nanotechnology Reviews

Biological Applications of Rare-Earth Based Nanoparticles

(2011) Cedric Bouzigues et al.   ACS Nano

Aptamer-Conjugated Nanoparticles for Cancer Cell Detection

(2011) Colin D. Medley et al.   ANALYTICAL CHEMISTRY

The golden age: gold nanoparticles for biomedicine

(2011) Erik C. Dreaden et al.   CHEMICAL SOCIETY REVIEWS

Red-luminescent europium (III) doped silica nanoshells: synthesis, characterization, and their interaction with HeLa cells

(2011) Jian Yang et al.   JOURNAL OF BIOMEDICAL OPTICS

Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma

(2011) Miriam Benezra et al.   JOURNAL OF CLINICAL INVESTIGATION

One-pot synthesis and characterization of dual fluorescent thiol-organosilica nanoparticles as non-photoblinking quantum dots and their applications for biological imaging

(2011) Michihiro Nakamura et al.   JOURNAL OF MATERIALS CHEMISTRY

Imaging of size-dependent uptake and identification of novel pathways in mouse Peyer's patches using fluorescent organosilica particles

(2011) Aziz Awaad et al.   Nanomedicine-Nanotechnology Biology and Medicine

In Vivo Biodistribution and Clearance Studies Using Multimodal Organically Modified Silica Nanoparticles

(2010) Rajiv Kumar et al.   ACS Nano

Recent Progress on Silica Coating of Nanoparticles and Related Nanomaterials

(2010) Andrés Guerrero-Martínez et al.   ADVANCED MATERIALS

Lanthanide doped silica nanoparticles applied to multiplexed immunoassays

(2010) Kathryn Murray et al.   ANALYST

Modern Views on Desilicification: Biosilica and Abiotic Silica Dissolution in Natural and Artificial Environments

(2010) Hermann Ehrlich et al.   CHEMICAL REVIEWS

Preparation and properties of silica–gold core–shell particles

(2010) Jerzy Choma et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

A novel one-step synthesis of Gd3+-incorporated mesoporous SiO2 nanoparticles for use as an efficient MRI contrast agent

(2010) Yuan-Zhi Shao et al.   Contrast Media & Molecular Imaging

Radioembolization Results in Longer Time-to-Progression and Reduced Toxicity Compared With Chemoembolization in Patients With Hepatocellular Carcinoma

(2010) Riad Salem et al.   GASTROENTEROLOGY

Tuning the Emission Properties of Ru(phen)32+Doped Silica Nanoparticles by Changing the Addition Time of the Dye during the Stöber Process

(2010) Dawei Zhang et al.   LANGMUIR

Silica-based nanoparticles for photodynamic therapy applications

(2010) Pierre Couleaud et al.   Nanoscale

Core-shell Fe3O4@SiO2nanoparticles synthesized with well-dispersed hydrophilic Fe3O4seeds

(2010) Chao Hui et al.   Nanoscale

Hypocrellin B doped and pH-responsive silica nanoparticles for photodynamic therapy

(2010) ZhaoBo Li et al.   Science China-Chemistry

A Comparative Analysis of Transarterial Downstaging for Hepatocellular Carcinoma: Chemoembolization Versus Radioembolization

(2009) R. J. Lewandowski et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Effective adsorption and separation of lysozyme with PAA-modified Fe3O4@silica core/shell microspheres

(2009) Dandan Shao et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Hybrid Cyanine−Silica Nanoparticles: Homogeneous Photoemission Behavior of Entrapped Fluorophores and Consequent High Brightness Enhancement

(2009) Gabriele Alberto et al.   Journal of Physical Chemistry C

Ru(bpy)3Covalently Doped Silica Nanoparticles as Multicenter Tunable Structures for Electrochemiluminescence Amplification

(2009) Simone Zanarini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional and Multifunctional Nanoparticles for Bioimaging and Biosensing

(2009) Subramanian Tamil Selvan et al.   LANGMUIR

Pp IX Silica Nanoparticles Demonstrate Differential Interactions withIn VitroTumor Cell Lines andIn VivoMouse Models of Human Cancers

(2009) Virginie Simon et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Incorporation of Iron Oxide Nanoparticles and Quantum Dots into Silica Microspheres

(2008) Numpon Insin et al.   ACS Nano

Covalently Dye-Linked, Surface-Controlled, and Bioconjugated Organically Modified Silica Nanoparticles as Targeted Probes for Optical Imaging

(2008) Rajiv Kumar et al.   ACS Nano

Multifunctional Inorganic Nanoparticles for Imaging, Targeting, and Drug Delivery

(2008) Monty Liong et al.   ACS Nano

In Vivo Study of Biodistribution and Urinary Excretion of Surface-Modified Silica Nanoparticles

(2008) Xiaoxiao He et al.   ANALYTICAL CHEMISTRY

Cellular responses to hyperthermia (40–46°C): Cell killing and molecular events

(2008) Joseph L. Roti Roti   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Optically and Magnetically Doped Organically Modified Silica Nanoparticles as Efficient Magnetically Guided Biomarkers for Two-Photon Imaging of Live Cancer Cells

(2008) Wing-Cheung Law et al.   Journal of Physical Chemistry C

Size-Controlled, One-Pot Synthesis, Characterization, and Biological Applications of Epoxy-Organosilica Particles Possessing Positive Zeta Potential

(2008) Michihiro Nakamura et al.   LANGMUIR

One-Pot Synthesis and Characterization of Three Kinds of Thiol−Organosilica Nanoparticles

(2008) Michihiro Nakamura et al.   LANGMUIR

Bioconjugated silica nanoparticles: Development and applications

(2008) Lin Wang et al.   Nano Research

Simple Synthesis of Functionalized Superparamagnetic Magnetite/Silica Core/Shell Nanoparticles and their Application as Magnetically Separable High-Performance Biocatalysts

(2008) Jinwoo Lee et al.   Small