The miRNA Content of Exosomes Released from the Glioma Microenvironment Can Affect Malignant Progression

Hypoxic cancer-secreted exosomal miR-182-5p promotes glioblastoma angiogenesis by targeting Kruppel-like factor 2 and 4

(2020) Nanxiang Xiong et al.   MOLECULAR CANCER RESEARCH

Re-education of the Tumor Microenvironment With Targeted Therapies and Immunotherapies

(2020) Shin Foong Ngiow et al.   Frontiers in Immunology

Reduced Expression of hsa-miR-338-3p Contributes to the Development of Glioma Cells by Targeting Mitochondrial 3-Oxoacyl-ACP Synthase (OXSM) in Glioblastoma (GBM)

(2020) Wen-Yi Wang et al.   OncoTargets and Therapy

Heterogeneity Matters: Different Regions of Glioblastoma Are Characterized by Distinctive Tumor-Supporting Pathways

(2020) Ivana Manini et al.   Cancers

MicroRNA‑10b‑5p downregulation inhibits the invasion of glioma cells via modulating homeobox B3 expression

(2019) Weiling Li et al.   Experimental and Therapeutic Medicine

Semaphorin-7A on Exosomes: A Promigratory Signal in the Glioma Microenvironment

(2019) Manini et al.   Cancers

Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-κB pathways

(2019) Mingyu Qian et al.   ONCOGENE

Exosomes and cancer: From oncogenic roles to therapeutic applications

(2019) Soheila Mohammadi et al.   IUBMB LIFE

SNHG29 regulates miR-223-3p/CTNND1 axis to promote glioblastoma progression via Wnt/β-catenin signaling pathway

(2019) Lizhang Han et al.   Cancer Cell International

let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7

(2019) Alice Buonfiglioli et al.   Cell Reports

Application of an Artificial Intelligence Algorithm to Prognostically Stratify Grade II Gliomas

(2019) Daniela Cesselli et al.   Cancers

Down-regulation of miRNA-320c promotes tumor growth and metastasis and predicts poor prognosis in human glioma

(2018) Qiao-Li Lv et al.   BRAIN RESEARCH BULLETIN

MicroRNA-320 Enhances Radiosensitivity of Glioma Through Down-Regulation of Sirtuin Type 1 by Directly Targeting Forkhead Box Protein M1

(2018) Tengfei Li et al.   Translational Oncology

Effect of Necrosis on the miRNA-mRNA Regulatory Network in CRT-MG Human Astroglioma Cells

(2018) So-Hee Ahn et al.   Cancer Research and Treatment

cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”

(2018) Daniel J. Brat et al.   ACTA NEUROPATHOLOGICA

miR-497/Wnt3a/c-jun feedback loop regulates growth and epithelial-to-mesenchymal transition phenotype in glioma cells

(2018) Fengfei Lu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

miR‑34a derived from mesenchymal stem cells stimulates senescence in glioma cells by inducing DNA damage

(2018) Qun Li et al.   Molecular Medicine Reports

miR-4516 predicts poor prognosis and functions as a novel oncogene via targeting PTPN14 in human glioblastoma

(2018) Tiantian Cui et al.   ONCOGENE

An NF-κB signature predicts low-grade glioma prognosis: a precision medicine approach based on patient-derived stem cells

(2017) Tamara Ius et al.   NEURO-ONCOLOGY

Transcription Factor NFAT5 Promotes Glioblastoma Cell-driven Angiogenesis via SBF2-AS1/miR-338-3p-Mediated EGFL7 Expression Change

(2017) Hai Yu et al.   Frontiers in Molecular Neuroscience

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

miR-182-5p Induced by STAT3 Activation Promotes Glioma Tumorigenesis

(2016) Jianfei Xue et al.   CANCER RESEARCH

Extracellular vesicle transfer of cancer pathogenic components

(2016) Yu Fujita et al.   CANCER SCIENCE

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

(2016) Michele Ceccarelli et al.   CELL

Expressions of Endocan in Patients with Meningiomas and Gliomas

(2016) Pinar Atukeren et al.   DISEASE MARKERS

miR-150-5p and miR-133a suppress glioma cell proliferation and migration through targeting membrane-type-1 matrix metalloproteinase

(2016) Moustafa Sakr et al.   GENE

Reduced expression of microRNA-497 is associated with greater angiogenesis and poor prognosis in human gliomas

(2016) Fuqiang Feng et al.   HUMAN PATHOLOGY

MicroRNA profiling of low-grade glial and glioneuronal tumors shows an independent role for cluster 14q32.31 member miR-487b

(2016) Heather Marion Ames et al.   MODERN PATHOLOGY

MicroRNA-34a inhibits cell proliferation and induces cell apoptosis of glioma cells via targeting of Bcl-2

(2016) JUNWEI DUAN et al.   Molecular Medicine Reports

MiR-126 Regulates the ERK Pathway via Targeting KRAS to Inhibit the Glioma Cell Proliferation and Invasion

(2016) Yang Li et al.   MOLECULAR NEUROBIOLOGY

The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas

(2016) D. F. Quail et al.   SCIENCE

Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation

(2016) Abdelnaby Khalyfa et al.   Oncotarget

Tumor exosome-mediated promotion of adhesion to mesothelial cells in gastric cancer cells

(2016) Tomohiro Arita et al.   Oncotarget

Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic Targets

(2016) Elena Codrici et al.   Stem Cells International

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

(2015) Lin Zhang et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Integrated genomic characterization of IDH1-mutant glioma malignant progression

(2015) Hanwen Bai et al.   NATURE GENETICS

Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

(2015) Jeanette E. Eckel-Passow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

DIANA-miRPath v3.0: deciphering microRNA function with experimental support

(2015) Ioannis S. Vlachos et al.   NUCLEIC ACIDS RESEARCH

Correlation of microRNA-10b upregulation and poor prognosis in human gliomas

(2015) Yuchen Ji et al.   TUMOR BIOLOGY

Decreased Expression of MiRNA-204-5p Contributes to Glioma Progression and Promotes Glioma Cell Growth, Migration and Invasion

(2015) Zhiqiang Xia et al.   PLoS One

A vaccine targeting mutant IDH1 induces antitumour immunity

(2014) Theresa Schumacher et al.   NATURE

Ionizing Radiation and Glioblastoma Exosomes: Implications in Tumor Biology and Cell Migration

(2014) W. Tris Arscott et al.   Translational Oncology

Exosomes secreted by human cells transport largely mRNA fragments that are enriched in the 3′-untranslated regions

(2013) Arsen O Batagov et al.   Biology Direct

Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review

(2013) Asfar S. Azmi et al.   CANCER AND METASTASIS REVIEWS

Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth

(2013) Lin Cheng et al.   CELL

Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog

(2013) Swetlana Sirko et al.   Cell Stem Cell

Proteoglycans and their roles in brain cancer

(2013) Anna Wade et al.   FEBS Journal

Expression level of human miR-34a correlates with glioma grade and prognosis

(2013) Haifeng Gao et al.   JOURNAL OF NEURO-ONCOLOGY

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Overexpressed let-7a inhibits glioma cell malignancy by directly targeting K-ras, independently of PTEN

(2013) X.-R. Wang et al.   NEURO-ONCOLOGY

microRNA-223 promotes the growth and invasion of glioblastoma cells by targeting tumor suppressor PAX6

(2013) BAI-SHENG HUANG et al.   ONCOLOGY REPORTS

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

(2013) P. Kucharzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glioma-Associated Stem Cells: A Novel Class of Tumor-Supporting Cells Able to Predict Prognosis of Human Low-Grade Gliomas

(2013) Evgenia Bourkoula et al.   STEM CELLS

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing

(2013) Piroon Jenjaroenpun et al.   PeerJ

Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types

(2012) Jasenka Guduric-Fuchs et al.   BMC GENOMICS

Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration

(2012) Valbona Luga et al.   CELL

TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets

(2012) Libing Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

CD44 in human glioma correlates with histopathological grade and cell migration

(2012) Tsuneyasu Yoshida et al.   PATHOLOGY INTERNATIONAL

Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

(2012) J. F. Nabhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-1289 and “Zipcode”-like Sequence Enrich mRNAs in Microvesicles

(2012) Mehmet Fatih Bolukbasi et al.   Molecular Therapy-Nucleic Acids

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Deadly Teamwork: Neural Cancer Stem Cells and the Tumor Microenvironment

(2011) Justin D. Lathia et al.   Cell Stem Cell

Exosomes/microvesicles: mediators of cancer-associated immunosuppressive microenvironments

(2011) Douglas D. Taylor et al.   Seminars in Immunopathology

MiRNA-451 plays a role as tumor suppressor in human glioma cells

(2010) Yang Nan et al.   BRAIN RESEARCH

Guidelines on management of low-grade gliomas: report of an EFNS-EANO* Task Force

(2010) R. Soffietti et al.   EUROPEAN JOURNAL OF NEUROLOGY

Hallmarks of cancer: Interactions with the tumor stroma

(2010) Kristian Pietras et al.   EXPERIMENTAL CELL RESEARCH

miR-221/222 promote malignant progression of glioma through activation of the Akt pathway

(2010) Kang   INTERNATIONAL JOURNAL OF ONCOLOGY

MicroRNA-21 Is a Downstream Effector of AKT That Mediates Its Antiapoptotic Effects via Suppression of Fas Ligand

(2010) Danish Sayed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Let-7 microRNA inhibits the proliferation of human glioblastoma cells

(2010) Soon-Tae Lee et al.   JOURNAL OF NEURO-ONCOLOGY

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

(2010) Xuan Zhou et al.   LABORATORY INVESTIGATION

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

miRBase: integrating microRNA annotation and deep-sequencing data

(2010) A. Kozomara et al.   NUCLEIC ACIDS RESEARCH

Selective Release of MicroRNA Species from Normal and Malignant Mammary Epithelial Cells

(2010) Lucy Pigati et al.   PLoS One

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes

(2009) Y. Li et al.   CANCER RESEARCH

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Co-suppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo

(2009) Kang   INTERNATIONAL JOURNAL OF ONCOLOGY

MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells

(2008) Hilah Gal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY