TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets

USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

(2012) Pieter J A Eichhorn et al.   NATURE MEDICINE

A20 Ubiquitin Ligase–Mediated Polyubiquitination of RIP1 Inhibits Caspase-8 Cleavage and TRAIL-Induced Apoptosis in Glioblastoma

(2012) Anita C. Bellail et al.   Cancer Discovery

MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop

(2011) Lili Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells

(2011) Deepa Subramanyam et al.   NATURE BIOTECHNOLOGY

miR-182 as a Prognostic Marker for Glioma Progression and Patient Survival

(2010) Lili Jiang et al.   AMERICAN JOURNAL OF PATHOLOGY

Smad7 and Smad6 bind to discrete regions of Pellino-1 via their MH2 domains to mediate TGF-β1-induced negative regulation of IL-1R/TLR signaling

(2010) Youn Sook Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Notch/Hes1 Pathway Sustains NF-κB Activation through CYLD Repression in T Cell Leukemia

(2010) Lluis Espinosa et al.   CANCER CELL

Expanding role of ubiquitination in NF-κB signaling

(2010) Siqi Liu et al.   CELL RESEARCH

miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors

(2010) Patryk Moskwa et al.   MOLECULAR CELL

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

(2010) Anna-Barbara Stittrich et al.   NATURE IMMUNOLOGY

Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth

(2010) Anita B. Hjelmeland et al.   PLOS BIOLOGY

TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma

(2009) Silvia Peñuelas et al.   CANCER CELL

RETRACTED: A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer Metastasis

(2009) Scott Valastyan et al.   CELL

CYLD: a tumor suppressor deubiquitinase regulating NF-κB activation and diverse biological processes

(2009) S-C Sun   CELL DEATH AND DIFFERENTIATION

Autocrine TGF-β Signaling Maintains Tumorigenicity of Glioma-Initiating Cells through Sry-Related HMG-Box Factors

(2009) Hiroaki Ikushima et al.   Cell Stem Cell

Increased IκBα expression is essential for the tolerogenic property of TGF-β-exposed APCs

(2009) Paiman Ghafoori et al.   FASEB JOURNAL

Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma

(2009) Ramin Massoumi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Direct activation of protein kinases by unanchored polyubiquitin chains

(2009) Zong-Ping Xia et al.   NATURE

Involvement of linear polyubiquitylation of NEMO in NF-κB activation

(2009) Fuminori Tokunaga et al.   NATURE CELL BIOLOGY

Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor

(2009) Miguel F. Segura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling to NF- B: Regulation by Ubiquitination

(2009) I. E. Wertz et al.   Cold Spring Harbor Perspectives in Biology

Altered TAB1:I B Kinase Interaction Promotes Transforming Growth Factor  -Mediated Nuclear Factor- B Activation during Breast Cancer Progression

(2008) J. R. Neil et al.   CANCER RESEARCH

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

The TGFß pathway as a therapeutic target in cancer

(2008) Joan Seoane   Clinical & Translational Oncology

Astrocyte Elevated Gene-1 is a Novel Prognostic Marker for Breast Cancer Progression and Overall Patient Survival

(2008) J. Li et al.   CLINICAL CANCER RESEARCH

The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

(2008) Alessandro Sorrentino et al.   NATURE CELL BIOLOGY

ABINs inhibit EGF receptor-mediated NF-κB activation and growth of EGF receptor-overexpressing tumour cells

(2008) L Huang et al.   ONCOGENE

Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

(2008) L. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the A20 OTU domain and mechanistic insights into deubiquitination

(2007) David Komander et al.   BIOCHEMICAL JOURNAL

Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20

(2007) Su-Chang Lin et al.   JOURNAL OF MOLECULAR BIOLOGY