Multifunctional Amyloids in the Biology of Gram-Positive Bacteria

The extracellular matrix protein TasA is a developmental cue that maintains a motile subpopulation within Bacillus subtilis biofilms

(2020) Nitai Steinberg et al.   Science Signaling

Dual functionality of the amyloid protein TasA in Bacillus physiology and fitness on the phylloplane

(2020) Jesús Cámara-Almirón et al.   Nature Communications

The biofilm-associated surface protein Esp of Enterococcus faecalis forms amyloid-like fibers

(2020) Agustina Taglialegna et al.   npj Biofilms and Microbiomes

Computational investigation for modeling the protein–protein interaction of TasA(28–261)–TapA(33–253): a decisive process in biofilm formation by Bacillus subtilis

(2020) Nidhi Verma et al.   JOURNAL OF MOLECULAR MODELING

The majority of the matrix protein TapA is dispensable for Bacillus subtilis colony biofilm architecture

(2020) Chris Earl et al.   MOLECULAR MICROBIOLOGY

Emerging Roles of Functional Bacterial Amyloids in Gene Regulation, Toxicity, and Immunomodulation

(2020) Nir Salinas et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Biofilm Formation and Synthesis of Antimicrobial Compounds by the Biocontrol Agent Bacillus velezensis QST713 in an Agaricus bisporus Compost Micromodel

(2019) Caroline Pandin et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Diverse Misfolded Conformational Strains and Cross-seeding of Misfolded Proteins Implicated in Neurodegenerative Diseases

(2019) Kwang Hun Lim   Frontiers in Molecular Neuroscience

Molecular architecture of bacterial amyloids in Bacillus biofilms

(2019) Nadia El Mammeri et al.   FASEB JOURNAL

Curli of Uropathogenic Escherichia coli Enhance Urinary Tract Colonization as a Fitness Factor

(2019) Víctor M. Luna-Pineda et al.   Frontiers in Microbiology

Amyloid protein produced by B. cereus CR4 possesses bioflocculant activity and has potential application in microalgae harvest

(2019) M. C. Sarang et al.   BIOTECHNOLOGY LETTERS

Bacterial Model Membranes Reshape Fibrillation of a Functional Amyloid Protein

(2018) Ravit Malishev et al.   BIOCHEMISTRY

Ecology and Biogenesis of Functional Amyloids in Pseudomonas

(2018) Sarah L. Rouse et al.   JOURNAL OF MOLECULAR BIOLOGY

Reciprocal Interactions between Membrane Bilayers and S. aureus PSMα3 Cross-α Amyloid Fibrils Account for Species-Specific Cytotoxicity

(2018) Ravit Malishev et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural changes of TasA in biofilm formation ofBacillus subtilis

(2018) Anne Diehl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell wall associated protein TasA provides an initial binding component to extracellular polysaccharides in dual-species biofilm

(2018) Danielle Duanis-Assaf et al.   Scientific Reports

Extreme amyloid polymorphism in Staphylococcus aureus virulent PSMα peptides

(2018) Nir Salinas et al.   Nature Communications

Listeriolysin O: A phagosome-specific cytolysin revisited

(2018) Brittney N. Nguyen et al.   CELLULAR MICROBIOLOGY

The Bacterial Extracellular Matrix Protein TapA Is a Two‐Domain Partially Disordered Protein

(2018) Razan Abbasi et al.   CHEMBIOCHEM

CalY is a major virulence factor and a biofilm matrix protein

(2018) Thomas Candela et al.   MOLECULAR MICROBIOLOGY

Functional amyloids in Streptococcus mutans, their use as targets of biofilm inhibition and initial characterization of SMU_63c

(2017) Richard N Besingi et al.   MICROBIOLOGY-SGM

Listeriolysin O: from bazooka to Swiss army knife

(2017) Suzanne E. Osborne et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril

(2017) Einav Tayeb-Fligelman et al.   SCIENCE

The role of microbial amyloid in neurodegeneration

(2017) Robert P. Friedland et al.   PLoS Pathogens

Should the biofilm mode of life be taken into consideration for microbial biocontrol agents?

(2017) Caroline Pandin et al.   Microbial Biotechnology

The propensity of the bacterial rodlin protein RdlB to form amyloid fibrils determines its function in Streptomyces coelicolor

(2017) Wen Yang et al.   Scientific Reports

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

(2016) Bruno Vasconcelos et al.   ACTA NEUROPATHOLOGICA

Amyloid Fibrils as Building Blocks for Natural and Artificial Functional Materials

(2016) Tuomas P. J. Knowles et al.   ADVANCED MATERIALS

Macroscopic amyloid fiber formation by staphylococcal biofilm associated SuhB protein

(2016) Anirudha Dutta et al.   BIOPHYSICAL CHEMISTRY

Amyloid Structures as Biofilm Matrix Scaffolds

(2016) Agustina Taglialegna et al.   JOURNAL OF BACTERIOLOGY

Biofilms: an emergent form of bacterial life

(2016) Hans-Curt Flemming et al.   NATURE REVIEWS MICROBIOLOGY

Dissecting the contribution of Staphylococcus aureus α-phenol-soluble modulins to biofilm amyloid structure

(2016) Patrizia Marinelli et al.   Scientific Reports

Functional amyloids as inhibitors of plasmid DNA replication

(2016) Laura Molina-García et al.   Scientific Reports

Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals

(2016) Agustina Taglialegna et al.   PLoS Pathogens

Adhesion mechanisms of curli subunit CsgA to abiotic surfaces

(2016) E. P. DeBenedictis et al.   Science Advances

Identification of a Supramolecular Functional Architecture ofStreptococcus mutansAdhesin P1 on the Bacterial Cell Surface

(2015) Kyle P. Heim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

(2015) Zane Jaunmuktane et al.   NATURE

Bacterial Amyloid Formation: Structural Insights into Curli Biogensis

(2015) Nani Van Gerven et al.   TRENDS IN MICROBIOLOGY

A genomic region involved in the formation of adhesin fibers in Bacillus cereus biofilms

(2015) Joaquín Caro-Astorga et al.   Frontiers in Microbiology

Aβ seeds resist inactivation by formaldehyde

(2014) Sarah K. Fritschi et al.   ACTA NEUROPATHOLOGICA

Pivotal roles for Streptomyces cell surface polymers in morphological differentiation, attachment and mycelial architecture

(2014) Marloes L. C. Petrus et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Functional Analysis of the Accessory Protein TapA in Bacillus subtilis Amyloid Fiber Assembly

(2014) D. Romero et al.   JOURNAL OF BACTERIOLOGY

The Calcium-induced Conformation and Glycosylation of Scavenger-rich Cysteine Repeat (SRCR) Domains of Glycoprotein 340 Influence the High Affinity Interaction with Antigen I/II Homologs

(2014) Sangeetha Purushotham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Programmable biofilm-based materials from engineered curli nanofibres

(2014) Peter Q. Nguyen et al.   Nature Communications

A Secreted Bacterial Protease Tailors the Staphylococcus aureus Virulence Repertoire to Modulate Bone Remodeling during Osteomyelitis

(2013) James E. Cassat et al.   Cell Host & Microbe

Surfactin triggers biofilm formation ofBacillus subtilisin melon phylloplane and contributes to the biocontrol activity

(2013) Houda Zeriouh et al.   ENVIRONMENTAL MICROBIOLOGY

Insight into structure-function relationship in phenol-soluble modulins using an alanine screen of the phenol-soluble modulin (PSM) α3 peptide

(2013) Gordon Y. C. Cheung et al.   FASEB JOURNAL

Isolation, Characterization, and Aggregation of a Structured Bacterial Matrix Precursor

(2013) Liraz Chai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Staphylococcus δ-toxin induces allergic skin disease by activating mast cells

(2013) Yuumi Nakamura et al.   NATURE

PSMs of Hypervirulent Staphylococcus aureus Act as Intracellular Toxins That Kill Infected Osteoblasts

(2013) Jean-Philippe Rasigade et al.   PLoS One

Bacillus subtilis biofilm induction by plant polysaccharides

(2013) P. B. Beauregard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SuhB Is a Regulator of Multiple Virulence Genes and Essential for Pathogenesis of Pseudomonas aeruginosa

(2013) K. Li et al.   mBio

Microanatomy at Cellular Resolution and Spatial Order of Physiological Differentiation in a Bacterial Biofilm

(2013) D. O. Serra et al.   mBio

Distinct Roles of Phenol-Soluble Modulins in Spreading of Staphylococcus aureus on Wet Surfaces

(2012) Eleni Tsompanidou et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biocontrol of tomato wilt disease byBacillus subtilisisolates from natural environments depends on conserved genes mediating biofilm formation

(2012) Yun Chen et al.   ENVIRONMENTAL MICROBIOLOGY

The potential use of toxin antibodies as a strategy for controlling acuteStaphylococcus aureusinfections

(2012) Gordon YC Cheung et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

SapB and the rodlins are required for development of Streptomyces coelicolor in high osmolarity media

(2012) Wouter Jong et al.   FEMS MICROBIOLOGY LETTERS

Role of Curli and Cellulose Expression in Adherence of Escherichia coli O157:H7 to Spinach Leaves

(2012) Dumitru Macarisin et al.   Foodborne Pathogens and Disease

Promiscuous Cross-seeding between Bacterial Amyloids Promotes Interspecies Biofilms

(2012) Yizhou Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microcin Amyloid Fibrils A Are Reservoir of Toxic Oligomeric Species

(2012) Mohammad Shahnawaz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Protein Oligomerization: Inhibitor of Functional Amyloids Templates α-Synuclein Fibrillation

(2012) Istvan Horvath et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional amyloid formation by Streptococcus mutans

(2012) M. W. Oli et al.   MICROBIOLOGY-SGM

The suhB gene of Burkholderia cenocepacia is required for protein secretion, biofilm formation, motility and polymyxin B resistance

(2012) R. Rosales-Reyes et al.   MICROBIOLOGY-SGM

Aerial development in Streptomyces coelicolor requires sortase activity

(2012) Andrew Duong et al.   MOLECULAR MICROBIOLOGY

Contribution of a harpin protein fromXanthomonas axonopodispv.citrito pathogen virulence

(2012) Germán G. Sgro et al.   MOLECULAR PLANT PATHOLOGY

Protein secretion and surface display in Gram-positive bacteria

(2012) O. Schneewind et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Curli Functional Amyloid Systems Are Phylogenetically Widespread and Display Large Diversity in Operon and Protein Structure

(2012) Morten S. Dueholm et al.   PLoS One

How Staphylococcus aureus biofilms develop their characteristic structure

(2012) S. Periasamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting of the central nervous system byListeria monocytogenes

(2012) Olivier Disson et al.   Virulence

Functional Amyloids Composed of Phenol Soluble Modulins Stabilize Staphylococcus aureus Biofilms

(2012) Kelly Schwartz et al.   PLoS Pathogens

Membrane assembly of the cholesterol-dependent cytolysin pore complex

(2011) Eileen M. Hotze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

pH dependence of listeriolysin O aggregation and pore-forming ability

(2011) Andrej Bavdek et al.   FEBS Journal

Crystal Structure of the C-terminal Region ofStreptococcus mutansAntigen I/II and Characterization of Salivary Agglutinin Adherence Domains

(2011) Matthew R. Larson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antimicrobial Activity of Community-associated Methicillin-resistantStaphylococcus aureusIs Caused by Phenol-soluble Modulin Derivatives

(2011) Hwang-Soo Joo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights into Functional and Pathological Amyloid

(2011) Frank Shewmaker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of Intracellular Tau Aggregation Is Promoted by  -Synuclein Seeds and Provides Novel Insights into the Hyperphosphorylation of Tau

(2011) E. A. Waxman et al.   JOURNAL OF NEUROSCIENCE

Direct and synergistic hemolysis caused by Staphylococcus phenol-soluble modulins: implications for diagnosis and pathogenesis

(2011) Gordon Y.C. Cheung et al.   MICROBES AND INFECTION

An accessory protein required for anchoring and assembly of amyloid fibres in B. subtilis biofilms

(2011) Diego Romero et al.   MOLECULAR MICROBIOLOGY

Dual amyloid domains promote differential functioning of the chaplin proteins during Streptomyces aerial morphogenesis

(2011) D. S. Capstick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the C-terminal domain of the surface antigen SpaP from the caries pathogenStreptococcus mutans

(2010) Åsa Nylander et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Sodium dodecyl sulfate–agarose gel electrophoresis for the detection and isolation of amyloid curli fibers

(2010) Chris Sitaras et al.   ANALYTICAL BIOCHEMISTRY

Human Formyl Peptide Receptor 2 Senses Highly Pathogenic Staphylococcus aureus

(2010) Dorothee Kretschmer et al.   Cell Host & Microbe

Molecular force probe measurement of antigen I/II-matrix protein interactions

(2010) Martine Soell et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Neutrophil responses to staphylococcal pathogens and commensals via the formyl peptide receptor 2 relates to phenol-soluble modulin release and virulence

(2010) Maren Rautenberg et al.   FASEB JOURNAL

The changing faces of Streptococcus antigen I/II polypeptide family adhesins

(2010) L. Jeannine Brady et al.   MOLECULAR MICROBIOLOGY

Functional amyloid in Pseudomonas

(2010) Morten S. Dueholm et al.   MOLECULAR MICROBIOLOGY

The biofilm matrix

(2010) Hans-Curt Flemming et al.   NATURE REVIEWS MICROBIOLOGY

Staphylococcus epidermidis Antimicrobial δ-Toxin (Phenol-Soluble Modulin-γ) Cooperates with Host Antimicrobial Peptides to Kill Group A Streptococcus

(2010) Anna L. Cogen et al.   PLoS One

Amyloid fibers provide structural integrity to Bacillus subtilis biofilms

(2010) D. Romero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenol‐Soluble Modulin α3 Enhances the Human Neutrophil Lysis Mediated by Panton‐Valentine Leukocidin

(2009) Isamu Hongo et al.   JOURNAL OF INFECTIOUS DISEASES

Selective Antimicrobial Action Is Provided by Phenol-Soluble Modulins Derived from Staphylococcus epidermidis, a Normal Resident of the Skin

(2009) Anna L. Cogen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Streptococcus Adherence and Colonization

(2009) A. H. Nobbs et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Attachment ofStreptomyces coelicoloris mediated by amyloidal fimbriae that are anchored to the cell surface via cellulose

(2009) Wouter de Jong et al.   MOLECULAR MICROBIOLOGY

Amyloid-Like Adhesins Produced by Floc-Forming and Filamentous Bacteria in Activated Sludge

(2008) P. Larsen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Listeria monocytogenes Biofilm-Associated Protein (BapL) May Contribute to Surface Attachment of L. monocytogenes but Is Absent from Many Field Isolates

(2008) S. J. Jordan et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genome Sequence of the Streptomycin-Producing Microorganism Streptomyces griseus IFO 13350

(2008) Y. Ohnishi et al.   JOURNAL OF BACTERIOLOGY

Function and Redundancy of the Chaplin Cell Surface Proteins in Aerial Hypha Formation, Rodlet Assembly, and Viability in Streptomyces coelicolor

(2008) C. Di Berardo et al.   JOURNAL OF BACTERIOLOGY

Formation of Pmel17 Amyloid Is Regulated by Juxtamembrane Metalloproteinase Cleavage, and the Resulting C-terminal Fragment Is a Substrate for γ-Secretase

(2008) Markus P. Kummer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Streptococcus mutans and Streptococcus intermedius Adhesion to Fibronectin Films Are Oppositely Influenced by Ionic Strength

(2008) Henk J. Busscher et al.   LANGMUIR

RNAIII-Independent Target Gene Control by the agr Quorum-Sensing System: Insight into the Evolution of Virulence Regulation in Staphylococcus aureus

(2008) Shu Y. Queck et al.   MOLECULAR CELL

Ecology and genomics of Bacillus subtilis

(2008) Ashlee M. Earl et al.   TRENDS IN MICROBIOLOGY