Listeriolysin O: from bazooka to Swiss army knife

Listeriolysin O Membrane Damaging Activity Involves Arc Formation and Lineaction -- Implication for Listeria monocytogenes Escape from Phagocytic Vacuole

(2016) Yi Ruan et al.   PLoS Pathogens

Avoidance of Autophagy Mediated by PlcA or ActA Is Required for Listeria monocytogenes Growth in Macrophages

(2015) Gabriel Mitchell et al.   INFECTION AND IMMUNITY

Directly Observing the Lipid-Dependent Self-Assembly and Pore-Forming Mechanism of the Cytolytic Toxin Listeriolysin O

(2015) Estefania Mulvihill et al.   NANO LETTERS

Glutathione activates virulence gene expression of an intracellular pathogen

(2015) Michelle L. Reniere et al.   NATURE

Strain-Specific Interactions of Listeria monocytogenes with the Autophagy System in Host Cells

(2015) Marija Cemma et al.   PLoS One

Plasticity of Listeriolysin O Pores and its Regulation by pH and Unique Histidine

(2015) Marjetka Podobnik et al.   Scientific Reports

Dealing with damage: Plasma membrane repair mechanisms

(2014) Annette Draeger et al.   BIOCHIMIE

Dependency of Caspase-1 Activation Induced in Macrophages by Listeria monocytogenes on Cytolysin, Listeriolysin O, after Evasion from Phagosome into the Cytoplasm

(2014) H. Hara et al.   JOURNAL OF IMMUNOLOGY

Multiple Nod-Like Receptors Activate Caspase 1 during Listeria monocytogenes Infection

(2014) S. E. Warren et al.   JOURNAL OF IMMUNOLOGY

Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread

(2014) Mark A. Czuczman et al.   NATURE

Damage control: cellular mechanisms of plasma membrane repair

(2014) Norma W. Andrews et al.   TRENDS IN CELL BIOLOGY

Crystal structure of listeriolysin O reveals molecular details of oligomerization and pore formation

(2014) Stefan Köster et al.   Nature Communications

Listeria monocytogenes Dampens the DNA Damage Response

(2014) Ascel Samba-Louaka et al.   PLoS Pathogens

Listeriaphospholipases subvert host autophagic defenses by stalling pre-autophagosomal structures

(2013) Ivan Tattoli et al.   EMBO JOURNAL

Fluxes of Ca2+and K+Are Required for the Listeriolysin O-Dependent Internalization Pathway of Listeria monocytogenes

(2013) Stephen Vadia et al.   INFECTION AND IMMUNITY

Membrane Chaperone SecDF Plays a Role in the Secretion of Listeria monocytogenes Major Virulence Factors

(2013) T. Burg-Golani et al.   JOURNAL OF BACTERIOLOGY

The Pore-Forming Toxin Listeriolysin O Is Degraded by Neutrophil Metalloproteinase-8 and Fails To Mediate Listeria monocytogenes Intracellular Survival in Neutrophils

(2013) E. Arnett et al.   JOURNAL OF IMMUNOLOGY

Structural Studies of Streptococcus pyogenes Streptolysin O Provide Insights into the Early Steps of Membrane Penetration

(2013) Susanne C. Feil et al.   JOURNAL OF MOLECULAR BIOLOGY

Efferocytosis Is an Innate Antibacterial Mechanism

(2012) Constance J. Martin et al.   Cell Host & Microbe

Activation of the unfolded protein response by Listeria monocytogenes

(2012) Helena Pillich et al.   CELLULAR MICROBIOLOGY

Listeria monocytogenes-Derived Listeriolysin O Has Pathogen-Associated Molecular Pattern-Like Properties Independent of Its Hemolytic Ability

(2012) Anu Wallecha et al.   Clinical and Vaccine Immunology

Chloride transport in functionally active phagosomes isolated from Human neutrophils

(2012) Martha L. Aiken et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role for Telomerase in Listeria monocytogenes Infection

(2012) Ascel Samba-Louaka et al.   INFECTION AND IMMUNITY

Allosteric mutants show that PrfA activation is dispensable for vacuole escape but required for efficient spread and Listeria survival in vivo

(2012) Caroline Deshayes et al.   MOLECULAR MICROBIOLOGY

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Listeriolysin O Is Strongly Immunogenic Independently of Its Cytotoxic Activity

(2012) Javier A. Carrero et al.   PLoS One

Membrane Damage during Listeria monocytogenes Infection Triggers a Caspase-7 Dependent Cytoprotective Response

(2012) Sara K. B. Cassidy et al.   PLoS Pathogens

Listeriolysin O Suppresses Phospholipase C-Mediated Activation of the Microbicidal NADPH Oxidase to Promote Listeria monocytogenes Infection

(2011) Grace Y. Lam et al.   Cell Host & Microbe

Regulation of Listeria virulence: PrfA master and commander

(2011) Aitor de las Heras et al.   CURRENT OPINION IN MICROBIOLOGY

pH dependence of listeriolysin O aggregation and pore-forming ability

(2011) Andrej Bavdek et al.   FEBS Journal

Posttranslocation Chaperone PrsA2 Regulates the Maturation and Secretion of Listeria monocytogenes Proprotein Virulence Factors

(2011) B. M. Forster et al.   JOURNAL OF BACTERIOLOGY

Functional analysis of the Listeria monocytogenes secretion chaperone PrsA2 and its multiple contributions to bacterial virulence

(2011) Francis Alonzo III et al.   MOLECULAR MICROBIOLOGY

An unstructured 5′-coding region of the prfA mRNA is required for efficient translation

(2011) Edmund Loh et al.   NUCLEIC ACIDS RESEARCH

Listeria monocytogenestransiently alters mitochondrial dynamics during infection

(2011) Fabrizia Stavru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Listeria monocytogenes exploits cystic fibrosis transmembrane conductance regulator (CFTR) to escape the phagosome

(2011) A. L. Radtke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pore-Forming Toxin Listeriolysin O Mediates a Novel Entry Pathway of L. monocytogenes into Human Hepatocytes

(2011) Stephen Vadia et al.   PLoS Pathogens

Recruitment of the Major Vault Protein by InlK: A Listeria monocytogenes Strategy to Avoid Autophagy

(2011) Laurent Dortet et al.   PLoS Pathogens

Listeria monocytogenes Triggers AIM2-Mediated Pyroptosis upon Infrequent Bacteriolysis in the Macrophage Cytosol

(2010) John-Demian Sauer et al.   Cell Host & Microbe

Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome

(2010) Sarah Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Listeriolysin O-Dependent Bacterial Entry into the Cytoplasm Is Required for Calpain Activation and Interleukin-1  Secretion in Macrophages Infected with Listeria monocytogenes

(2010) S. R. Dewamitta et al.   INFECTION AND IMMUNITY

Listeria monocytogenes PrsA2 Is Required for Virulence Factor Secretion and Bacterial Viability within the Host Cell Cytosol

(2010) F. Alonzo et al.   INFECTION AND IMMUNITY

Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes in Caspase-1 Activation by Listeria monocytogenes

(2010) Jianghong Wu et al.   JOURNAL OF CLINICAL IMMUNOLOGY

CFTR-mediated halide transport in phagosomes of human neutrophils

(2010) Richard G. Painter et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pro-autophagic signal induction by bacterial pore-forming toxins

(2010) Nicole Kloft et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Listeria monocytogenes impairs SUMOylation for efficient infection

(2010) David Ribet et al.   NATURE

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Listeriolysin O Is Necessary and Sufficient to Induce Autophagy during Listeria monocytogenes Infection

(2010) Nicole Meyer-Morse et al.   PLoS One

Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface

(2010) A. J. Farrand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A trans-Acting Riboswitch Controls Expression of the Virulence Regulator PrfA in Listeria monocytogenes

(2009) Edmund Loh et al.   CELL

Human  -Defensins Inhibit Hemolysis Mediated by Cholesterol-Dependent Cytolysins

(2009) R. I. Lehrer et al.   INFECTION AND IMMUNITY

Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted byBacillus anthracis

(2009) Raymond W. Bourdeau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Listeria monocytogenes-Infected Human Peripheral Blood Mononuclear Cells Produce IL-1 , Depending on Listeriolysin O and NLRP3

(2009) K. Meixenberger et al.   JOURNAL OF IMMUNOLOGY

The innate immunity role of cathepsin-D is linked to Trp-491 and Trp-492 residues of listeriolysin O

(2009) Eugenio Carrasco-Marín et al.   MOLECULAR MICROBIOLOGY

Listeria monocytogenes ActA-mediated escape from autophagic recognition

(2009) Yuko Yoshikawa et al.   NATURE CELL BIOLOGY

In Vivo Transcriptional Profiling of Listeria monocytogenes and Mutagenesis Identify New Virulence Factors Involved in Infection

(2009) Ana Camejo et al.   PLoS Pathogens

Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens

(2008) Zijiang Zhao et al.   Cell Host & Microbe

Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles

(2008) Cheryl L. Birmingham et al.   NATURE

GILT is a critical host factor for Listeria monocytogenes infection

(2008) Reshma Singh et al.   NATURE

Autophagic control of listeria through intracellular innate immune recognition in drosophila

(2008) Tamaki Yano et al.   NATURE IMMUNOLOGY